Publications by authors named "Hai-Wang Zhang"
The amyloid-beta (Aβ) aggregation in Alzheimer's disease (AD) triggers neuroinflammation, and neurodegeneration, which lead to cognitive deficits along with other neuropsychiatric symptoms, including depression and anxiety. G protein-coupled receptor 35 (GPR35) is expressed in the brain and is involved in metabolic stresses. However, the role of GPR35 in AD pathogenesis remains unknown.
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- Shenmai injection (SMI) is a Traditional Chinese Medicine made from ophiopogonis radix and ginseng radix rubra, showing promise in improving treatment outcomes for dilated cardiomyopathy (DCM) when used alongside conventional medicine.
- A systematic review and meta-analysis is planned to collect and evaluate data from various medical databases to validate SMI's effectiveness as a treatment for DCM.
- The study aims to provide comprehensive, high-quality evidence supporting the use of SMI as an adjunct treatment for DCM patients.