Publications by authors named "Hai-Ting Zhao"

Article Synopsis
  • Low-temperature proton exchange membrane fuel cells (PEMFCs) need very pure hydrogen gas because they are highly sensitive to carbon monoxide (CO) contamination.
  • A surface modification technique was developed, applying a 0.5-0.91 nm amorphous carbon nitride layer on PtRu/C substrates, improving hydrogen transport while blocking CO diffusion.
  • This modification significantly reduces CO adsorption, maintaining stable catalyst operation for over 20 hours even with high CO levels (1000 ppm), and allows stable performance in PEMFCs with CO concentrations up to 10 ppm, surpassing the standard limit of 0.2 ppm.
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Article Synopsis
  • Sudden Unexpected Death in Epilepsy (SUDEP) is a significant cause of mortality in epilepsy patients, with unclear underlying mechanisms that hinder effective prevention and treatment.
  • Current animal models used in SUDEP research have limitations due to differences between species, which affects their ability to accurately replicate the complex human condition.
  • The review proposes creating an ideal SUDEP model using brain-computer interfaces and artificial intelligence to enhance understanding of SUDEP's pathogenesis and advance prevention strategies.
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The study identified the blood-entering components of Sijunzi Decoction after gavage administration in rats by UPLC-Q-TOF-MS/MS, and investigated the mechanism of Sijunzi Decoction in treating Alzheimer's disease by virtue of network pharmacology, molecular docking, and experimental verification. The blood-entering components of Sijunzi Decoction were identified based on the mass spectra and data from literature and databases. The potential targets of the above-mentioned blood-entering components in the treatment of Alzheimer's disease were searched against PharmMapper, OMIM, DisGeNET, GeneCards, and TTD.

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Sudden unexpected death in epilepsy (SUDEP) is the leading cause of death among patients with epilepsy. However, the underlying mechanism of SUDEP remains elusive. Previous studies showed seizure-induced respiratory arrest (S-IRA) is the main factor in SUDEP, and that enhancement of serotonin (5-HT) function in the dorsal raphe nucleus (DR) can significantly reduce the incidence of S-IRA in the DBA/1 mouse model of SUDEP.

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Sudden unexpected death in epilepsy (SUDEP) is the leading cause of mortality in patients with intractable epilepsy. However, the pathogenesis of SUDEP seems to be poorly understood. Our previous findings showed that the incidence of seizure-induced respiratory arrest (S-IRA) was markedly reduced by atomoxetine in a murine SUDEP model.

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Objective: Identifying the factors that are correlated with and predictive of reduced quality of life (QOL) is essential to optimize the treatment of epilepsy and the management of comorbidities.

Methods: We analyzed the independent associations between the Quality of Life in Epilepsy-31 (QOLIE-31) inventory and the demographic, clinical, psychiatric, and cognitive variables of 47 consecutive patients with temporal lobe epilepsy (TLE). Predictors of the correlated variables were analyzed by multiple linear regression analysis.

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