Immunization of BALB/c Mice with Killed Tachyzoites of against Acute Toxoplasmosis.

Background: with widespread distribution infects over one third of human populations in the world and can cause serious life-threatening diseases especially for the immunodeficient patients in acute toxoplasmosis. As the clinical pharmaceutical drugs with severe side effects for treatment and non-ideal extant vaccines for prevention, more work starves to be done for keeping advantages in the athletics.

Methods: Aluminum adjuvant and hybrid formaldehyde-killed tachyzoites of RH and GT1 isolates were prepared to intramuscularly immunize BALB/c mice for five times at 0, 3, 7, 14 and 21 days post first injection.

Ultrasound features affecting the sample adequacy after fine-needle aspiration of thyroid nodules with different risk stratification.

Background: The inadequacy samples caused by the internal characteristic structure of thyroid nodules are difficult to be solved.

Objective: To evaluate the ultrasound features affecting the sample adequacy after fine-needle aspiration (FNA) of thyroid nodules with different risk stratification.

Methods: 592 thyroid nodules that underwent ultrasound-guided FNA were included in this retrospective study.

Toxoplasma invasion delayed by TgERK7 eradication.

Toxoplasma gondii causes serious clinical toxoplasmosis in humans mostly due to its asexual life cycles, which can be artificially divided into five tightly coterminous stages. Any radical or delay for the stage will result in tremendous changes immediately behind. We previously demonstrated that TgERK7 is associated with the intracellular proliferation of T.

Immune Responses Induced by pVAX/ERK7 against Infection in BALB/c Mice.

Background: can infect all the warm-blooded vertebrates and cause serious toxoplasmosis. Extracellular signal-regulated kinase 7 in (ERK7) mediated the proliferation of this parasite may be a potential vaccine candidate. Thus, immune responses induced by ERK7 were investigated in this study using a DNA vaccine strategy.

Devitalization of the immune mapped protein 1 undermines the intracellular proliferation of Toxoplasma gondii.

The intracellular protozoan Toxoplasma gondii infects approximately one-third of the world's population as well as various animals, causing toxoplasmosis. However, there remains a need to define the functions of newly identified genes of T. gondii.

Immunization with plasmid DNA expressing Heat Shock Protein 40 confers prophylactic protection against chronic Toxoplasma gondii infection in Kunming mice.

Toxoplasma gondii causes one of the most common protozoal diseases of humans and animals worldwide. With the aim of designing an effective vaccine against T. gondii infection, we examined the immunogenicity of a DNA vaccine expressing heat shock protein 40 (HSP40) against challenge with T.