[Evaluation of kinematic capability of different groups by detecting oxygen saturation of muscle using near infrared spectroscopy].

Based on the principles of organizational optics, the noninvasive tissue oxygenation saturation monitor was developed. The monitor was used to continuously monitor the changes in regional oxygen index of the thigh vastus lateralis in 101 volunteers, who performed an incremental intensity exercise on bicycle ergometer. Among the volunteers, 42 are athletes, 25 are patients whose spleens are asthenic, and the other 34 are controls.

[Evaluation of heart impact in the 100 m extreme intensity sport using near-infrared non-invasive muscle oxygen detecting device and sports heart rate detection technology].

Using continuous two wavelength near-infrared technology to detect the variation in the consistency of oxygen hemoglobin in the muscle and the sports heart rate wireless real time collection technology, we devised the real time muscle tissue oxygenation and instantaneous heart rate experiment scheme and implemented it for the process of the 100 m run with two parameters given simultaneously. The experiment shows that the concentration of the oxygen hemoglobin in the muscle tissue continues decreasing after the end of the 100 m run, and the time interval between the moment when the concentration of the oxygen hemoglobin attains the minimum value and the moment when the athletes finish the 100 m run is (6.65 +/- 1.

[Noninvasive detection of the concentrations of pigments in pork tissue using near infrared spectroscopy].

Based on the absorption spectra of hemoglobin and myoglobin in the near infrared band, the concentrations of these pigments in the biological tissues can be obtained using near infrared spectroscopy (NIRS) by detecting the intensity attenuation of the emitted light compared with the incident light. Based on the steady-state spatially resolved NIRS, the prototype for detecting the concentrations of tissue hemoglobin and myoglobin was independently developed by our group. The probe consisted of an LED light source which could emit three different wavelengths in the near infrared band, and two detectors which were placed on the same line with and at the distances of 30/40 mm to the LED.

[Comparison of the models of acute hypoxia and hypoxic-ischemia in newborn piglets].

Objective: To compare the newborn piglet models of hypoxic ischemic brain damage in hypoxia and hypoxia combined with occlusion of both carotid arteries.

Methods: Twenty four 7-day-old piglets were divided into two groups. Group H: mechanical ventilation with low concentration of oxygen, Group HI: mechanical ventilation with low concentration of oxygen combined with occlusion of both carotid arteries.

[Evaluating fatigue resistance effect of health food by near-infrared tissue oximeter].

Currently, chronic fatigue syndrome (CFS) seriously affects people's normal living and work. In the present paper, the physiological parameters, such as tissue oxygenation saturation and heart rate, were used to evaluate the subjects' fatigue degree, and the fatigue resistance capsule and coffee were taken as a measure to adjust the fatigue. Human tissue oxygen saturation (rSO2) can be monitored noninvasively and in real time by near infrared spectroscopy (NIRS) based on spatially-resolved spectroscopy.

[Pseudo color method for the infrared thermogram display of local breast focus tissue].

An infrared thermogram which reflects the human body surface temperature distribution can be obtained through detecting the infrared thermal radiation from each point on the human body surface. When a malignant tumor occurs in a breast, it will cause an increase in the prominent temperature in the breast surface focus region due to the abnormal blood transmission state of local focus tissue. Breast cancer can be detected through the visual analysis of the focus regions by physicians.

[Detecting cerebral hypoxia-ischemia of newborn piglets using spatially-resolved near-infrared spectroscopy].

As a non-invasive technique for measuring tissue oxygenation, near-infrared spectroscopy (NIRS) has increasing applications in detecting cerebral hypoxia-ischemia. The authors, introduced the basic principle of the NIRS oximeter developed independently by our group (TSAH-100). The authors achieved the optimal coupling between the probe and the detected cerebral tissue.

[Application of near infrared spectroscopy in monitoring blood oxygen saturation of fibula flaps].

Objective: To study the change of tissue oxygen index (TOI) by non-invasive near infrared spectroscopy (NIRS) and to investigate the blood flow variety of fibula flaps after operation.

Methods: Thirty-six patients who accepted fibula flap reconstruction were chosen as subjects. Authors measured the TOI of the fibula flaps and the control side every four hours in the first twenty-four hours, and measured these positions with the intermittence of twelve hours from second to eighth day after operation.

[Optimally designing the probe of the near infrared oximeter to detect human tissue oxygen saturation non-invasively].

Human tissue oxygen saturation (rSO2) can be monitored non-invasively and in real time by near infrared spectroscopy (NIRS) based on spatially-resolved spectroscopy. To expand the clinical applications of the NIRS oximeter developed by our group based on the above principle, the accuracy of rSO2 must be ensured and enhanced as far as possible. In the present paper, the influences of the probe configuration, especially the distance between the detectors and the wavelength discreteness of the light source, on the accuracy of rSO2 were discussed.

Evaluation of near infrared spectroscopy in monitoring postoperative regional tissue oxygen saturation for fibular flaps.

The ability of near infrared spectroscopy (NIRS) to predict vascular compromise in vascular free flaps postoperatively has been assessed, and the extent of regional tissue oxygen saturation (rSO(2)) after fibular flap transplantation was investigated quantitatively. To validate the sensibility and precision of the technique, the following methods were used. (1) Forearm vessel obstructive tests were conducted in four healthy volunteers.

[Correlation of brain hypoxia at different degrees with brain function and brain damage investigated using near infrared spectroscopy].

Objective: To study correlation of brain hypoxia of different degrees with brain function and damage.

Methods: The brain regional oxygen saturation (rSO2) was determined by using a non-invasive near infrared spectroscopy (NIRS) technique in 15 piglets; the piglets were subjected to inhale 3% - 11% oxygen-nitrogen mixed gas through mechanical ventilation for 30 min. The piglets were divided into groups according to the level of brain rSO2 (i.

[The preliminary study for testing freshness of meat by using near-infrared reflectance spectroscopy].

The value of the volatile basic nitrogen of meat is an important index to determine the freshness of meat. It is difficult to meet the demand of fast and non-destructive measurement by means of classical semimicro-quantitative nitrogent method. A model to predict the value of the volatile basic nitrogen based on near-infrared reflectance spectroscopy was established.

[Evaluation of early cognitive ability of infants born preterm by near-infrared spectroscopy].

Objective: To compare the differences in cerebral oxygenation responses between the infants born preterm and full-term infants and to evaluate the early cognitive ability of infants born preterm.

Methods: Cerebral oxygenation after light stimulation was detected by near infrared spectroscopy (NIRS) in preterm infants at 3 or 6 months corrected gestational age (GA). The results were compared with those of age-matched infants born at term.

[Monitoring cerebral oxygenation using near infrared spectroscopy during cardiopulmonary bypass surgery].

To avoid cerebral hypoxia caused by the imbalance between cerebral oxygen supply and consumption, regional cerebral oxygenation of patients need to be monitored at real time during cardiopulmonary bypass (CPB) surgery, and the physiological parameters can be regulated and emergent treatment can be used according to it. Using the near infrared (NIR) instrument developed by our group, cerebral oxygenation of the patients under cardiac surgery was monitored. The instrument consists of a two-wavelength near infrared light source and two near infrared detectors.

[Evaluation of relationship between early brain response and neurodevelopment in newborns by using near infrared spectroscopy].

Objective: To study the relationship between early brain response to extrinsic stimulation and neurodevelopment in preterm infants, assess the brain function of preterm infants in the early stage, and thereby to provide objective evidence for the degree of neurodevelopment in preterm infants and to evaluate prognosis.

Methods: Using near infrared spectroscopy (NIRS), the brain response to sound stimulation of 90 preterm infants at different gestational age was observed and compared with the result obtained from 20 full term infants. The neonatal behavioral neurological assessment (NBNA) was performed at corrected age of 40 weeks, and the infants were followed up for 2 years.

[Regional cerebral oxygen saturation in neonates with meconium aspiration syndrome].

Objective: This study examined the changes of regional cerebral oxygen saturation (rSO2) by noninvasive near infrared spectrophotometry in neonates with meconium aspiration syndrome (MAS).

Methods: Seventy-three full neonates with MAS were divided into three groups by respiratory symptoms: asymptomatic group (group 1, n=38), common group (group 2, n=28) and severe group (group 3, n=7). Near infrared spectrophotometry was used to measure the cerebral rSO2 on days 1, 3, 5 and 7 after birth.

[Non-invasive determination of the optical properties of neonatal brain].

The absorption andreduced scattering parameters of tissue can provide information on a variety of physiologic processes. In the present paper, the local optical properties of 23 infant foreheads were measured with a two-wavelength (788 and 832 nm) portable frequency-domain NIR spectroscopic techinque, based on a standard reference phantom with known optical properties. The single source-detector separation is 40 mm.

[Spectral colorimetric correction of full view color images in a real scene measurement system].

In the three dimensional multiple modalities scanning real scene measurement system, a color linear CCD was used to obtain the one dimensional linear color information of the scene. Successive one dimensional color images of different angles were patched to constitute the full view color image. If the color image is displayed directly on the color cathode ray tube (CRT) monitor of a computer, colorimetric distortion will occur.

Charge couple device-based system for 3-dimensional real time positioning on the assessment of segmental range of motion of lumbar spine.

Objective: To observe the tested results of the segmental range of motion (ROM) of lumbar spine by charge couple device (CCD)-based system for 3-dimensional real-time positioning (CCD system), and to analyze its clinical significance.

Methods: Seven patients with lumbar joint dysfunction and 8 healthy subjects were tested twice by the CCD-based system with an interval of 10 min.

Results: The ROM of the patients was obviously lesser than that of the healthy subjects.

[Simultaneous measurement of muscle energy metabolism by MRS and frequency-domain NIR spectroscopy].

The frequency-domain near-infrared spectrometry (NIRS) is capable of measuring the absolute absorption and reduced scattering coefficient of tissue noninvasively. This allows the quantitation of tissue hemoglobin concentration which reflects the balance between oxygen delivery and oxygen utilization of the skeletal muscle. Phosphorus magnetic resonance spectroscopy (31P-MRS) has become a gold standard of noninvasive measurement of human skeletal muscle metabolism.

[Application of near-infrared spectroscopy to postoperative monitoring of flap in plastic surgery].

As a non-invasive technique for the measurement of blood and oxygen in tissue, the near-infrared spectroscopy (NIRS) has an increasing application to the postoperative monitoring of plastic surgery. In authorial research, a set of NIRS oximeter has been used in 6 successful flap-transplantation operations to monitor and contrast the oxygen saturation in the free flap side and in the normal opposite side. It was found in the research that there is a notable difference in the oxygen saturation between those two sides.

In vivo determination of the optical properties of infant brain using frequency-domain near-infrared spectroscopy.

We investigate the optical properties of the brain in 23 neonates in vivo using a frequency domain near-infrared spectroscopy (NIRS). In this study, a calibration procedure is employed to determine the absorption and reduced scattering coefficients with single source-detector separation. The absorption coefficients of the infant foreheads are lower than the values reported in adults.

[Small-invasive photoelectric detection of blood glucose].

A new type of photoelectric small-invasive blood glucose monitor was developed. This instrument is based on a 16 bit microprocessor MSP430F413 which belongs to a low-power microprocessor of the component family of Texas Instruments promotion recently. There are three advantages of this instrument: (1) using the method of two optical beams to decrease the influence of the LED's power fluctuation, (2) using the multiple comparative method to determine the terminative time of enzymatic reaction and the start time of computing and processing, (3) to store a lot of measured data up to 50 samples.

[Measurement and statistical analysis of the vertical force in normal young people's gait].

Objective: To find a method for evaluating the relationship between mechanical data and gait efficiently.

Method: Gait mechanical data of 27 young men (20-22 years) without history of the kinetic diseases were collected using a force-measuring system. The data were transformed into characteristic two-peak curves in vertical direction (z-axis).

[The preliminary study on noninvasive detection using NIR diffusion reflectance spectrum for monitoring blood glucose].

The noninvasive detection method using near-infrared diffusion reflectance spectrum for monitoring blood glucose was described. A group of healthy volunteers(2 young male and 2 young female) was tested twenty-six times under changing of both the blood glucose concentration and spectrum region during various states. In order to set up a model, the set was chosen from these samples, the set of prediction was not belong to the set of the model.