Multicenter study of diagnostic procedures, genetic aberration analysis, and first-line treatment of lung cancer in Jiangsu Province, China.

Background: Jiangsu Province, China, is highly developed economically and culturally, and has a high prevalence of lung cancer. We aimed to evaluate the diagnostic procedures, genetic aberration analysis status, and first-line treatment models of lung cancer in Jiangsu Province.

Methods: Lung cancer patients diagnosed in 2016 at 22 tertiary care hospitals were evaluated.

[Methods for the identification of horizontal gene transfer (HGT) events and progress in related fields].

Horizontal gene transfer is the gene exchange between different organisms or different organelles, which occurs frequently in prokaryotes. Many newly identified horizontal transfer events in eukaryotes indicates that it is a common phenomenon in all organisms. This paper describes the concept of horizontal gene transfer, the standard for judging a horizontal gene transfer events, the character, the mode, the way of horizontal gene transfer, and its impact on gene and genome evolution.

[Study on the screening of lactamase and its fermentation conditions].

(-)-gamma-Lactam is one of the key starting materials for the synthesis (-)-cabovir and (-)-abacavir, which serve as two powerful antiviral agents. The production of gamma-lactam using enzymatic resolution of racemic gamma-lactam was attempted in the paper. 20 out of 69 strains capable of producing lactamase were screened from soil samples collected in several districts throughout Beijing; particularly N-actylphenylalanine was used as sole carbon source in the screening method.