Publications by authors named "Hai-Qin Xu"
Article Synopsis
- The study aimed to compare the effectiveness of reduced intensity conditioning (RIC) versus myeloablative conditioning (MAC) in stem cell transplantation for hematologic malignancies, focusing on survival rates and complications.
- After analyzing data from 29 studies with 6235 patients, results showed that RIC had better overall survival at one year but lower disease-free survival rates after two years compared to MAC.
- While RIC also had fewer instances of severe acute graft-versus-host disease and lower treatment-related mortality, it was associated with a higher relapse rate; overall, RIC was found to be equivalent or better than MAC in terms of overall survival but fell short in disease-free survival in the long run.
The aim of the study was to compare the therapeutic efficacy of total body irradiation (TBI)/cyclophosphamide (CY) versus BU/CY as conditioning regimen for leukemia. We electronically searched the Cochrane Central Register of Controlled Trials, Medline, Embase, CIBMTR and critically appraised all relevant articles (1990.01-2009.
View Article and Find Full Text PDFObjective: The aim of this meta-analysis is to compare the HLA disparities and the outcome of UCBT, i.e. the disease-free survival (DFS), engraftment, graft-versus-host disease, (GVHD), and transplantation related mortality (TRM).
View Article and Find Full Text PDF[Comparison of total body irradiation-cyclophosphamide versus busulphan-cyclophosphamide as conditioning regimens for myelogenous leukemia: a meta-analysis].
Zhongguo Shi Yan Xue Ye Xue Za Zhi
December 2008
Article Synopsis
- * A meta-analysis of 9 clinical trials, involving 3039 patients, was conducted to evaluate factors like stem cell engraftment, complications, and disease-free survival rates between the two treatment groups.
- * Findings show no significant difference in engraftment failure and mortality, but higher complications were observed in both groups; TBI/CY had a lower relapse rate in acute myeloid leukemia (AML) but higher in chronic myeloid leukemia