Publications by authors named "Hai-Qin Fang"
Amanita neoovoidea (genus Amanita Pers.) poisoning leads to acute renal failure. Here, we present seven case reports of acute renal failure with acute hepatic failure due to ingestion of A.
View Article and Find Full Text PDFObjective: The present study was undertaken to evaluate the subchronic toxicity of lanthanum and to determine the no observed adverse effect level (NOAEL), which is a critical factor in the establishment of an acceptable dietary intake (ADI).
Methods: In accordance with the Organization for Economic Co-operation and Development (OECD) testing guidelines, lanthanum nitrate was administered once daily by gavage to Sprague-Dawley (SD) rats at dose levels of 0, 1.5, 6.
Subchronic toxicity study of yttrium nitrate by 90-day repeated oral exposure in rats.
Regul Toxicol Pharmacol
November 2017
Concerns regarding the adverse effects of long-term exposure to low levels of rare earth elements (REEs) from foods on human health have arisen in recent years. Nevertheless, no official acceptable daily intake (ADI) has yet been proposed for either total REEs or individual REE. In accordance with the Organization for Economic Co-operation and Development (OECD) testing guideline, the present study was undertaken to evaluate the subchronic toxicity of yttrium, a representative heavy REE with higher contaminated level in foods in China, to achieve a no observed adverse effect level (NOAEL) which is a critical basis for the establishment of an ADI.
View Article and Find Full Text PDF[Development of human embryonic stem cell platforms for human health-safety evaluation].
Beijing Da Xue Xue Bao Yi Xue Ban
February 2016
Article Synopsis
- Human embryonic stem cells (hESCs) are considered a premier source for generating various body cells and tissues, recognized by global health authorities for their regenerative capabilities.
- The study involved differentiating hESCs into various types of human cells, and assessing the safety of different substances on these cells.
- Results indicated that hESC-derived cellular platforms were more sensitive and accurate for testing human health and safety compared to currently used cell models.
Neurobehavioral Assessment of Rats Exposed to Yttrium Nitrate during Development.
Biomed Environ Sci
April 2015
Objective: The aim of this study was to assess the effects of yttrium nitrate on neurobehavioral development in Sprague-Dawley rats.
Methods: Dams were orally exposed to 0, 5, 15, or 45 mg/kg daily of yttrium nitrate from gestation day (GD) 6 to postnatal day (PND) 21. Body weight and food consumption were monitored weekly.