Publications by authors named "Hai-Ping Lin"

Purpose: Neoadjuvant chemoradiotherapy (nCRT) is a standard treatment option for patients with stage III oesophageal cancer. Approximately 30% of oesophageal cancer patients will have a pathological complete response (pCR) after nCRT. However, available clinical methods cannot accurately predict pCR for patients.

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  • Circular RNAs (CircRNAs), particularly hsa_circ_0003823, are being investigated for their roles in cancer, specifically in esophageal squamous cell carcinoma (ESCC) and its resistance to the drug Apatinib.
  • The study used RNA sequencing and various assays to show that hsa_circ_0003823 is elevated in ESCC tissues and is linked to poor patient outcomes, promoting tumor growth and spread.
  • By targeting microRNA-607, hsa_circ_0003823 enhances the expression of CRISP3, leading to reduced sensitivity to Apatinib, highlighting a potential therapeutic target for overcoming drug resistance in ESCC.
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  • * The study analyzed 54 patients with locally advanced esophageal squamous cell carcinoma (ESCC) who underwent various imaging techniques (DW-MRI and F-FDG PET/CT) before, during, and after nCRT, comparing results between those who achieved a pathological complete response (pCR) and those who did not.
  • * Results showed significant differences in metabolic tumor volume and other imaging parameters between patients with pCR and non-pCR, suggesting that functional imaging could enhance predictive
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  • Post-stroke depression (PSD) is a common complication after a stroke, and this study aims to create a quantitative diagnosis model using Traditional Chinese Medicine (TCM) to enhance clinical treatment and understanding of PSD.
  • The research will identify key symptoms and their relationships to different stages of PSD, aiming to clarify the evolution of TCM syndromes over time.
  • By analyzing patient data from a specific hospital, the study will develop a model using artificial neural networks to standardize TCM diagnosis for PSD.
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Excess activation and expression of large-conductance Ca(2+)-activated K(+) channels (BKCa channels) may be an important mechanism for delayed neuronal death after cerebral ischemia/reperfusion injury. Electroacupuncture can regulate BKCa channels after cerebral ischemia/reperfusion injury, but the precise mechanism remains unclear. In this study, we established a rat model of cerebral ischemia/reperfusion injury.

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Aim: The anatomic characters and applicability of the extended pterional transtemporal transtentorial (EPTT) approach versus the subtemporal transtentorial (ST) approach for surgical treatment of petroclival tumors were evaluated.

Material And Methods: Ten sides from five adult Chinese injected cadavers were manipulated using both two approaches. Four deep bony anatomic landmarks were specified in the skull base to create two adjoining triangles that were respectively located in the anterior and posterior petroclival region.

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Objective: To investigate the distribution and the antimicrobial resistance of the bacteria, mycoplasma and Chlamydia trachomatis isolated from the prostatic secretion of infertile men with chronic prostatitis, and to provide clinicians with grounds for choosing antibiotic agents.

Methods: The bacteria obtained were isolated and identified, the Chlamydia trachomatis was detected by FLO-PCR, and the results were analysed statistically.

Results: In 1 186 specimens of EPS, the total positive rate of isolates was 51.

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Objective: To investigate the feasibility of tracheal reconstruction with a prosthesis made of memory alloy coated with collagen sponge in mongrel dogs.

Method: The basic skeleton of the prosthesis was knitted with Ni-Ti memory alloy wires. The tubular mesh was sealed with polyurethane membrane and then inner and external walls of the lumen were coated with collagen sponge.

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It is difficult to perform a primary anastomosis when a pathological trachea is over-lengnthing resected. Thus the tracheal prosthesis is required to apply in the airway reconstruction. Severe defects in the early tracheal prosthesis result in failure of surgery.

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In this study, 18S rDNA and ITS-5.8S rDNA regions of four Shiraia bambusicola isolates collected from different species of bamboos were amplified by PCR with universal primer pairs NS1/NS8 and ITS5/ITS4, respectively, and sequenced. Phylogenetic analyses were conducted on three selected datasets of rDNA sequences.

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