Publications by authors named "Hai-Peng Si"

Alveolar soft-part sarcoma (ASPS) is a rare malignant soft tissue tumor of uncertain cellular origin. We reported the case of a 21-year-old man with ASPS presenting itself as a markedly vascular tumor of the prostate. Immunohistochemistry showed positive nuclear staining for TFE3, positive cytoplasm staining for MyoD1 and neuron-specific enolase, and negative for S100, CK, synaptophysin, chromogranin A, myogenin and PSA.

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We present a novel surface-enhanced Raman scattering (SERS) substrate based on graphene oxide/silver nanoparticles/copper film covered silicon pyramid arrays (GO/AgNPs/PCu@Si) by a low-cost and simple method. The GO/AgNPs/PCu@Si substrate presents high sensitivity, good homogeneity and well stability with R6G molecules as a probe. The detected concentration of Rhodamine 6 G (R6G) is as low as 10 M.

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Background: We previously showed that nano-hydroxyapatite/carboxymethyl chitosan (n-Ha/CMCS) displayed excellent mechanical properties, good degradation rates and exceptional biocompatibility, with negligible toxicity. The aim of this study was to determine the effect of the same composite with vascular endothelial growth factor (VEGF)- transfected bone marrow stromal cells (BMSCs) in a rabbit radial defect model.

Methods: The nano-hydroxyapatite was produced through co-precipitation.

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Article Synopsis
  • The study aimed to investigate how the protein hepcidin affects the stability of atherosclerotic plaques.
  • In experiments with mice lacking a specific protein, overexpression of hepcidin led to increased macrophage infiltration into plaques and reduced levels of collagen and smooth muscle cells, making the plaques less stable.
  • Hepcidin was found to enhance inflammation and oxidative stress in macrophages, particularly in the presence of oxidized low-density lipoprotein (ox-LDL), and contributed to the destabilization of atherosclerotic plaques through the retention of iron.
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