Importance: Rotavirus vaccines have been introduced worldwide, and the clinical association of different rotavirus vaccines with reduction in rotavirus gastroenteritis (RVGE) after introduction are noteworthy.
Objective: To evaluate the comparative benefit, risk, and immunogenicity of different rotavirus vaccines by synthesizing randomized clinical trials (RCTs) and observational studies.
Data Sources: Relevant studies published in 4 databases: Embase, PubMed, the Cochrane Library, and Web of Science were searched until July 1, 2020, using search terms including "rotavirus" and "vaccin*.
Importance: The conclusions from the multiple randomized clinical trials exploring the relationship between development of intussusception and rotavirus vaccination among neonates and infants have been controversial.
Objective: To evaluate the association between rotavirus vaccination and risk of intussusception.
Data Sources: For this systematic review and meta-analysis, PubMed, Web of Science, Cochrane library, and Embase databases were searched from January 1, 1999, through December 31, 2018, using no language restrictions.
Background: Preclinical studies have demonstrated that β-adrenergic receptor antagonists could improve the prognosis of breast cancer. However, the conclusions of clinical and pharmacoepidemiological studies have been inconsistent. This review was conducted to re-assess the relationship between beta-adrenoceptor blockers and breast cancer prognosis.
View Article and Find Full Text PDFA sand culture experiment was conducted to study the salt tolerance of 13 cotton cultivars at their germinating and seedling stages under the stress of different concentration NaCl, and a cluster analysis was made on the salt tolerance, according to the subjection values of salt toxicity coefficients of multi-indices and the sum subjection value. It was observed that the appropriate concentration of NaCl for the evaluation of salt tolerance was 150 mmol x L(-1). The salt tolerance differed with cultivar and growth stage.
View Article and Find Full Text PDFObjective: The aims of this study were to detect serum proteomic patterns in gastric cancer serum samples using Surface-enhanced Laser Desorption/ionization-Time-of-flight-Mass Spectrometry ProteinChip array technology, to screen biomarker candidates, to build diagnostic models and to evaluate their clinical significance.
Methods: Serum samples from patients with gastric cancer and normal healthy control subjects (n = 125) were analysed using surface-enhanced laser desorption/ionization technology. The spectra were generated on weak cation exchange (WCX2) chips, and protein peak clustering and classification analyses were established using Ciphergen Biomarker Wizard and Biomarker Pattern software, respectively.
Zhonghua Xue Ye Xue Za Zhi
September 2004
Objective: To study the changes of platelet in May-Hegglin anomaly (MHA) and the molecular pathogenesis mechanism.
Methods: Peripheral blood was drawn from the MHA proband, her father and her uncle. Platelet count and morphology were examined by automatic blood cell counter and microscopy, respectively.