Analysis of the heavy metal contents' effect on steroidal saponins and the anti-breast cancer activity of var. .

var. , as a near-threatened and ethnic medicine in China, used to be a key ingredient in traditional Chinese medicine in treatment of traumatic injuries, sore throat, snakebites, and convulsions for thousands of years. However, there were no reports on the inverse relationship between the contents of heavy metals and saponins and its anti-breast cancer pharmacological activity in var.

Characterization and Immunogenicity of Recombinant A. flavus Uox Modified by Co/EDTA Carbon Dots.

Background: Uricase (Uox) is a major drug in gout and a supplementary drug in cancer treatment. Because allergic reactions caused by Uox limit its clinical application,10% Co/EDTA was used to chemically modify Uox from A. flavus to reduce its immunogenicity.

Semi-supervised Long-tail Endoscopic Image Classification.

Objective To explore the semi-supervised learning (SSL) algorithm for long-tail endoscopic image classification with limited annotations. Method We explored semi-supervised long-tail endoscopic image classification in HyperKvasir, the largest gastrointestinal public dataset with 23 diverse classes. Semi-supervised learning algorithm FixMatch was applied based on consistency regularization and pseudo-labeling.

Steady-State Based Model of Airborne Particle/Gas and Settled Dust/Gas Partitioning for Semivolatile Organic Compounds in the Indoor Environment.

Indoor semivolatile organic compounds (SVOCs), present in the air, airborne particles, settled dust, and other indoor surfaces, can enter the human body through several pathways. Knowing the partitioning between gaseous and particulate phases is important in identifying specific pathway contributions and thereby accurately assessing human exposure. Numerous studies have developed equilibrium equations to predict airborne particle/gas (P/G) partitioning in air () and dust/gas (D/G) partitioning in settled dust ().

The complete chloroplast genome and phylogenetic analysis of matsuda (Malvaceae).

Matsuda is an economically and medicinally important plant. Here, we report the first chloroplast (cp) genome of the genus (). The complete cp genome is 159,878 bp in length with an overall GC content of 36.

The complete chloroplast genome and phylogenetic analysis of Craib (Leguminosae).

In this study, we used high-throughput sequencing technology to sequence and functionally annotate the chloroplast genome of . The total length of chloroplast genome is 152,115 bp with the typical quadripartite structure. It contains two inverted repeats (IRa and IRb) of 26,233 bp each, which are separated by a large single-copy (LSC) region of 82,024 bp and a small single-copy (SSC) region of 17,625 bp.

The complete chloroplast genome sequences and phylogenetic analysis of (Leguminosae).

The complete chloroplast genome of was obtained using the high-throughput sequencing technology in this article. The complete chloroplast genomes of this species were 152,658 bp in length, consisting of a large single-copy region (LSC) of 83,652 bp and a small single-copy region (SSC) of 18,028 bp, which were separated by a pair of inverted repeat (IRs) regions of 25,489 bp. The chloroplast genome contained 111 unique genes, including 77 protein-coding genes, 30 genes, and four genes.

The complete chloroplast genome of DC. (Rutaceae) and its phylogenetic analysis.

We sequenced the complete chloroplast genome of via high-throughput sequencing technology, and analyzed its structural characteristics and phylogenetic relationships. The chloroplast exhibits a genome length of 158,473 bp, including a pair of inverted repeat regions (IRa and IRb) of 27,369 bp, a small single-copy (SSC) region of 17,629 bp and a large single-copy (LSC) region of 85,570 bp. The annotation analysis identified 112 genes, containing 78 protein-coding genes, 30 tRNA genes and 4 rRNA genes.

Identification of risk factors of developing pressure injuries among immobile patient, and a risk prediction model establishment: A protocol for systematic review.

Backgroud: Pressure injuries (PIs) bring a considerable physical and mental burden on immobile patients, and have put families and government under tremendous pressure to cover the cost of treatment. Therefore, this protocol proposes to identify risk factors of developing PIs in immobile patients from systematic reviews (SRs) and clinical practice guidelines (CPGs), in order to establish a risk prediction model for developing PIs and identify individual risk factors that can be modified to aid prevention.

Methods: Electronic databases and specific databases for CPGs and SRs will be searched.

Interpretations and comments for expert consensus on the diagnosis and treatment of heat stroke in China.

Heat stroke is the most severe type of heat illness, it is often accompanied by severe multiorgan damage and has a high fatality rate. In January 2020, based on new research evidence and the experiences of Chinese experts in heat stroke, the Expert Group of Heat Stroke Prevention and Treatment of the Chinese People's Liberation Army (PLA) and the Professional Committee of Critical Care Medicine of the Chinese PLA jointly issued a new Expert Consensus on the Diagnosis and Treatment of Heat Stroke in China. This article aims to interpret and supplement the major updates to the new consensus.

Seasonal variation and influence factors of organophosphate esters in air particulate matter of a northeastern Chinese test home.

To investigate the seasonal variation of organophosphate esters (OPEs) in air particulate matter (PM) and the corresponding influence factors in indoor environment, 104 indoor PM samples were collected in a test home, Harbin, China, from March 2017 to March 2018. The ΣOPEs concentrations ranged from 0.41 ng/m to 940 ng/m.

Phthalates in infant cotton clothing: Occurrence and implications for human exposure.

Clothing easily adsorbed the chemicals in the environment, and became a source of human exposure to chemicals. However, large contacted surface area and long exposure duration have elevated human exposure to chemicals from clothing, such as phthalates. Among them, cotton clothing, which infants prefer to wear, has been proven to adsorb phthalates more easily than other fabrics.

Semi-volatile organic compounds in infant homes: Levels, influence factors, partitioning, and implications for human exposure.

While infants are developing, they are easily affected by toxic chemicals existing in their environments, such as semi-volatile organic compounds (SVOCs): phthalates, polycyclic aromatic hydrocarbons (PAHs), polybrominated diphenyl ethers (PBDEs), and organophosphate esters (OPEs). However, the specific living environment of infants, including increased plastic products and foam floor mats, may increase the presence of these chemicals. In this study, 68 air, dust, and window film samples were collected from homes, with 3- to 6-month-old infant occupants, to analyze phthalates, PAHs, PBDEs, and OPEs.

[Start-up and Performance Recovery of Granular Sludge for Phosphorus Removal and Nitrification].

In this experiment, to determine the characteristics of low carbon and nitrogen water quality in domestic sewage, a sequencing batch reactor (SBR) was used to realize the stable operation of dephosphorization-nitrosation, by inoculating the enhanced biological phosphorus removal granular sludge, which was stored at low temperature. The sludge was activated by control of the aeration intensity and sludge age, which provided water for the influent of a CANON or anaerobic ammonia oxidation (ANAMMOX) process. In the experiment, when the concentration of dissolved oxygen was 6.

Organophosphate flame retardants in college dormitory dust of northern Chinese cities: Occurrence, human exposure and risk assessment.

Organophosphate flame retardants (OPFRs) are widely added to consumer products and building materials, which may pose potential health risk to humans. But information on their contamination and human exposure in the indoor environment especially dormitories in northern China is rare. In this study, twelve OPFRs were investigated in college dormitory dust that collected from Harbin, Shenyang, and Baoding, in northern China.

[Adjusting Temperature and Settling Time to Achieve ANAMMOX Particles Rapid Start-up and Stable Operation].

At room temperature (21-25℃), the long start-up time of anaerobic ammonium oxidation (ANAMMOX) granular sludge is the main problem preventing the practical application of this technology. This experiment aimed to cultivate the anaerobic ammonia oxidizing granular sludge in the SBR reactor by adjusting the temperature. After the start-up of the ANAMMOX, stable operation was achieved by changing hydraulic retention time (HRT) and the concentration of the inflow water substrate.

Pegylated Interferon-α Plus Ribavirin Therapy Improves Left Ventricular Diastolic Dysfunction in Patients With Chronic Hepatitis C Attaining Sustained Virological Response.

Background: Pegylated interferon (pegIFN) in combination with ribavirin (RBV) has successfully improved the rate of sustained virological response (SVR) in chronic hepatitis C virus (HCV) infected individuals, which reduces the progression of the chronic liver disease. However, the influence of combination therapy (pegIFN/RBV) on cardiac function has yielded ambiguous results. The present study aimed to evaluate the effects of combination therapy with pegIFN/RBV on cardiac function of HCV-infected individuals with SVR.

Functional and proteomic comparison of different techniques to produce equine anti-tetanus immunoglobulin F(ab')2 fragments.

Tetanus is still a major cause of human deaths in several developing countries. In particular, the neonatal form remains a significant public health problem. According to the World Health Organization, administration of tetanus toxoid is recommended for neonatal tetanus patients.

Occurrence, sources and human exposure assessment of SCCPs in indoor dust of northeast China.

Short-chain chlorinated paraffins (SCCPs) are widely used chemicals in household products and might cause adverse human health effects. However, limited information is available on the occurrence of SCCPs in indoor environments and their exposure risks on humans. In this study the concentrations, profiles and human exposure of SCCPs in indoor dust from five different indoor environments, including commercial stores, residential apartments, dormitories, offices and laboratories were characterized.

The dynamics and mechanism of the antimicrobial activity of tea tree oil against bacteria and fungi.

Tea tree oil (TTO) is a yellow liquid extracted from Melaleuca alternifolia. Although the antimicrobial activity of TTO has been known for a long time, its specific antimicrobial effects and mechanism underlying these remain poorly characterized. The present study investigated the chemical composition of TTO and the dynamics and mechanism of its antimicrobial activities in two bacterial and two fungal strains.

Phthalate Esters in Indoor Window Films in a Northeastern Chinese Urban Center: Film Growth and Implications for Human Exposure.

Indoor window film samples were collected in buildings during 2014-2015 for the determination of six phthalate diesters (PAEs). Linear regression analysis suggested that the film mass was positively and significantly correlated with the duration of film growth (from 7 to 77 days). PAEs were detected in all window film samples (n = 64).

Phthalates in dormitory and house dust of northern Chinese cities: Occurrence, human exposure, and risk assessment.

Phthalates are widely used chemicals in household products, which severely affect human health. However, there were limited studies emphasized on young adults' exposure to phthalates in dormitories. In this study, seven phthalates were extracted from indoor dust that collected in university dormitories in Harbin, Shenyang, and Baoding, in the north of China.