Publications by authors named "Hai-Li Bao"
Article Synopsis
- * Researchers have developed recombinant pseudorabies virus (PRV) that can express a full-length E2 protein, which is crucial for creating effective vaccines.
- * The study shows that a modified full-length E2 protein can stimulate stronger immune responses in mice and rabbits, indicating potential for a new bivalent vaccine that protects against both PR and CSF.
Pseudorabies (PR) and classical swine fever (CSF) are economically important infectious diseases of pigs. Most pig farms in China are immunized against these two diseases. Here, we describe a stabilized E2 protein as an immunogen inserted into the PRV genome as a bivalent live virus-vectored vaccine.
View Article and Find Full Text PDFPolydatin ameliorates hepatic ischemia-reperfusion injury by modulating macrophage polarization.
Hepatobiliary Pancreat Dis Int
February 2024
Background: Polydatin, a glucoside of resveratrol, has shown protective effects against various diseases. However, little is known about its effect on hepatic ischemia-reperfusion (I/R) injury. This study aimed to elucidate whether polydatin protects liver against I/R-induced injury and to explore the underlying mechanism.
View Article and Find Full Text PDFBackground & Aims: BCAT1 initiates the catabolism of branched-chain amino acids. Here, we investigated the function of BCAT1 and its transcriptional regulatory mechanism in hepatocellular carcinoma (HCC).
Methods: RNASeq was used to evaluate BCAT1 mRNA levels in HCC and normal matched specimens.
CIP2A is highly expressed in a variety of malignancies. We determined the expression and clinical significance of CIP2A in patients with advanced gastric cancer. CIP2A protein was expressed in 25 of 37 cancer tissue specimens.
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