World J Gastrointest Oncol
November 2023
Background: Studies evaluating the characteristics of dual primary gastric and colorectal cancer (CRC) (DPGCC) are limited.
Aim: To analyze the clinicopathologic characteristics and prognosis of synchronous and metachronous cancers in patients with DPGCC.
Methods: From October 2010 to August 2021, patients with DPGCC were retrospectively reviewed.
Objective: A large body of experimental and clinical observations indicates that disturbances in cerebral blood flow (CBF) and impaired cerebrovascular autoregulation are important in the pathogenesis of germinal matrix-intraventricular hemorrhage (GMH-IVH) and periventricular leukomalacia (PVL), the 2 most important forms of brain injury in pretmature infants. Near-infrared spectroscopy (NIRS) has been used recently to estimate CBF in human newborns. The objectives of this study were to evaluate the correlation of NIRS estimations and cerebral blood flow in newborn piglets, which in turn may help provide the ideal NIRS estimation reflecting the changes of cerebral blood flow and cerebrovascular autoregulation.
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