2.79-µm efficient acousto-optic Q switched Er,Cr:YSGG laser with an LiNbO crystal modulator.

We fabricate a novel, to the best of our knowledge, acousto-optic Q switch in the 3-micron wavelength range using a longitudinal acoustic mode in a lithium niobate (LiNbO) crystal. The device is designed based on properties of the crystallographic structure and material to obtain a high diffraction efficiency close to the theoretical prediction. The effectiveness of the device is verified by application in an Er,Cr:YSGG laser at 2.

High-peak-power electro-optically Q-switched laser with a gradient-doped Nd:YAG crystal.

We report on a high-peak-power electro-optically -switched laser emitting a near-diffraction-limited beam profile at 1064 nm by using a gradient-doped Nd:YAG crystal. The gradient-doped crystal features a unique combination of a reduced thermal lens effect through effectively spreading the heat load distribution within its volume. Its performance is compared with those of Nd:YAG crystals with uniform volume doping distribution operating in the -switched regime with the same laser configuration, demonstrating the higher average and peak power achievable with the gradient-doped crystal.

The Impact of Gene Polymorphisms on Anticoagulation Control With Warfarin.

Differences in warfarin maintenance dosages based on the presence of polymorphisms in VKORC1, CYP2C9, CYP4F2, and ORM1 can be determined through dosage adjustment according to routine guidelines. Little is known about whether routine therapy could provide consensus anticoagulation control for patients with different genotypes. This study was carried out to compare anticoagulant control in patients with different genotypes.

Correlation between Plasma Level of Monocyte Chemotactic Protein 1 and Acute Aortic Dissection.

Objective: To investigate the potential association between monocyte chemotactic protein 1(MCP-1)in plasma and acute aortic dissection(AAD).

Methods: A total of 110 patients with Stanford type A AAD who had received emergent surgical treatment in Xiangya hospital from September 2011 to September 2014 were enrolled in as the study group;meanwhile,110 patients with simple hypertension who had received treatment in department of cardiology were chosen as the control group. The plasma level of MCP-1 was measured and then compared between these two groups.

Chest wall tumors: Diagnosis, treatment and reconstruction.

The aim of the present study was to determine a suitable procedure for the treatment of chest wall neoplasms with less potential risk and an increased rate of survival. Fifty patients with suspected chest wall malignancies were analyzed using various preliminary investigation tools. Whole-chest scanning was performed in all the patients.

[Role of spinal MAPK-ERK signal pathway in myocardial ischemia-reperfusion injury].

Objective: To explore the role of spinal MAPK-ERK signal pathway in myocardial ischemia-reperfusion (I/R) injury.

Methods: Sixty male Sprague-Dawley(SD) rats (80-100 g) were randomly divided into 3 groups: sham (n=10), PD98059 (n=25) and I/R groups (n=25). Three days after successful intrathecal implantation, 5 μg DMSO was injected intrathecally into the sham group, and then the left coronary arteries were separated without being tied.

Influence of ORM1 polymorphisms on the maintenance stable warfarin dosage.

Purpose: ORM1 is a plasma drug binding protein. Its polymorphism rs17650 (S>F) has been reported to be an important factor affecting the binding ability and effect of antiretroviral protease inhibitors. The aim of this study was to determine whether the ORM1 rs17650 polymorphism also influences warfarin therapy.

[Rapid detection of residual cyclohexanone in disposable medical devices by ultraviolet photoionization ion mobility spectrometry (UV-IMS)].

In the manufacture of disposable PVC medical devices, cyclohexanone is frequently used as an adhesive reagent, which can be released into the tube airspace or stored solution and thus may cause some adverse effects on patients in therapy. In this paper, an ultraviolet photoionization ion mobility spectrometry (UV-IMS) technique has been developed to detect cyclohexanone through monitoring the gas composition within a package of infusion sets. The concentrations of cyclohexanone were prepared by means of exponential dilution method, and the experiments show that the UV-IMS has a limit of detection at 15 ppb and its measurable linear dynamics range is over three orders of magnitude.

[Photoionization ion mobility spectrometry (UV-IMS) for the isomeric volatile organic compounds].

The construction and performance study is reported for a newly developed ultraviolet photoionization ion mobility spectrometry (UV-IMS). In the present paper, an UV-IMS technique was firstly developed to detect eleven isomeric volatile organic compounds including the differences in the structure of carbon chain, the style of function group and the position of function group. Their reduced mobility values were determined and increased in this order: linears < branches < cycles, primary < secondary < tertiary, para- < meta- < ortho- and alcohols < acetones < aromas.

[Effects of tetramethylpyrazine on thrombin-induced tissue factor expression in vascular endothelial cells].

Objective: To observe the effects of tetramethylpyrazine (TMP) on tissue factor (TF) expression induced by thrombin in human umbilical vein endothelium derived cell line ECV304.

Methods: The changes in the total cellular procoagulant activity (PCA) of ECV304 cells exposed to thrombin were observed with one-stage clotting assay. TF mRNA expression in the exposed cells was examined using semi-quantitative reverse transcription-polymerase chain reaction (RT-PCR).

[Cardiopulmonary protection of ischemic postconditioning in cardiac surgery in children with tetralogy of Fallot].

Objective: Ischemic postconditioning effectively minimizes the ischemic/reperfusion injury, and the large series of case reports on its protective effects in cardiac surgery are limited. A randomized trial was conducted to investigate the effect of ischemic postconditioning on cardiopulmonary protection in children undergoing cardiac surgery for tetralogy of Fallot.

Methods: One hundred and five-children with tetralogy of Fallot undergoing surgery were randomly assigned to control (n=58) and ischemic postconditioning groups (n=47).

[Change of vWF, PAl-1 and t-PA in rats with hyperlipemia and its significance].

Objective: To establish the hyperlipoidemia model and observe its effect on the expression of plasma vWF, PAl-1 and t-PA after endothelial cell injury caused by the model at different time in rats.

Methods: Sixty male Sprague-Dawley rats weighing (200+/-20)g were randomly divided into 6 groups (n=10 in each): high flat composition for 7 weeks (Group A7), 8 weeks (Group A8)and 9 weeks(Group A9), common bait vessel feeding for 7 weeks(Group C7), 8 weeks(Group C8) and 9 weeks (Group C9). When it reached the setting time, the rats were put to death and the serum was separated to detect the blood-fat immediately.

[Fifty-three cases of valve repair for mitral insufficiency].

Objective: To summarize the experience of mitral vavuloplasty for mitral insufficiency in 53 patients.

Methods: Between January 2001 and September 2006,53 patients (31 males and 22 females) with mitral insufficiency underwent mitral valve repair at our hospital. The mean age was (23.

[Ion mobility spectrometry for the isomeric volatile organic compounds].

Ion mobility spectrometry (IMS) is based on determining the drift velocities, which the ionized sample molecules attain in the weak electric field of a drift tube at atmospheric pressure. The drift behavior can be affected by structural differences of the analytes, so that ion mobility spectrometry has the ability to separated isomeric compounds. In the present article, an introduction to IMS is given, followed by a description of the instrument used for the experiments to differentiate isomeric compounds.

[Discharge ion mobility spectrometry of ketonic organic compounds].

Ion mobility spectrometry (IMS) is a sensitive technique for fast on-line monitoring trace volatile organic compounds based upon the mobilities of gas phase ions at ambient pressure in weak electric field. In the present work, protonated water reactant ions were successfully prepared, and eight ketones were studied on a homemade high-resolution IMS apparatus using a discharge ionization source. The reduced mobility values of all ions were derived from the observed ion mobility spectra.

[Mechanical valve replacement in children with heart valve diseases].

Objective: To determine the surgical point and technique of artificial mechanical valve replacement in children with heart valve diseases.

Methods: From Jan. 1989 to Oct.

[Surgical treatment of cor triatriatum in 15 patients].

Objective: To review the clinical data of pathological morphology, diagnosis, surgical treatment of cor triatriatum in 15 patients.

Methods: Fifteen patients with a mean age of (14.6+/-10.

Pretreatment with aminophylline reduces release of Troponin I and neutrophil activation in the myocardium of patients undergoing cardioplegic arrest.

Objective: Cardioplegic arrest and subsequent reperfusion results in myocardial injury partly related to local inflammation in the heart. It has been proven that aminophylline has numerous anti-inflammatory effects. This study has been designed to evaluate the effects of aminophylline used as a cardioprotective agent for patients undergoing cardiopulmonary bypass (CPB) for valve replacement.

Proteomic analysis of secreted proteins of non-small cell lung cancer.

Background & Objective: Secreted proteins from cancer cells may be potential serologic biomarkers of cancer. It's important to globally identify secreted proteins of cancer cells. This study was to identify secreted proteins of lung cancer cells.

Proteomics-based identification of secreted protein dihydrodiol dehydrogenase as a novel serum markers of non-small cell lung cancer.

Identification of secreted proteins of lung cancer could provide new candidates of serum biomarkers for cancer diagnosis and prognosis evaluation. In this study, non-small cell lung cancer (NSCLC) cell line A549 was cultured. Proteins in the conditioned medium of A549 were recovered and the proteome analysis was subsequently performed.

[Changes of plasma von Willebrond factor and soluble E-selectin levels in patients with coronary artery disease].

Objective: To observe the changes of plasma von Willebrand factor (vWF) and soluble E-selectin (sE-selectin) in patients with coronary artery disease (CAD) and evaluate their clinic significance.

Methods: The level of plasma vWF and sE-selectin of 60 cases with coronary artery disease were detected by enzyme-linked immunosorbent assay (ELISA) and 20 healthy persons acted as the control group. Risk factors for coronary artery disease were obtained by asking the medical history and the relation ship was analyzed with coronary artery disease.

[Effect of glutathione pretreatment on lung ischemia-reperfusion injury during cardiopulmonary bypass].

Objective: To observe the clinical effect of glutathione (GSH) pretreatment on lung ischemia-reperfusion injury during cardiopulmonary bypass (CPB) and determine the mechanism.

Methods: Sixteen patients ready to replace heart valve(s) were randomly divided into the control and the treatment group. GSH diluted with normal saline solution was injected to the patients in the treatment group 36 h before the operation, while normal saline solution was injected to the patients in the control group.

[Surgical treatment of congenital heart disease complicated with infective endocarditis].

Objective: To review the experience of surgical treatment and the diagnosis of 41 patients with congenital heart diseases complicated with infective endocarditis.

Methods: Twenty-three males and 18 females (the mean age 22.6 years) were studied.