Publications by authors named "Hai-Guo Zhang"

Relapsed or refractory T-cell acute lymphoblastic leukemia/lymphoma (r/r T-ALL/LBL) are frequently aggressive and associated with unfavorable prognoses. Pan-targeted Chimeric Antigen Receptor (CAR) T-cell therapy have shown promising results in clinical trials. In recent years, CD7 CAR T-cell and CD5 CAR T-cell demonstrate effectiveness in treating r/r T-ALL/LBL patients with bone marrow infiltration.

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Objective: To study the prevalence of asthma in Qinghai Province between 2006 to 2007.

Methods: According to the geographical location and the altitude (1920 - 4500 m), stratified-cluster-random sampling was use for this study. A total of 27 851 individuals were investigated by household survey at 49 locations in 4 autonomous prefectures, Xining Municipal City and Haidong Administrative District.

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Completion of a survey of dermatoglyphic variables for all ethnic groups in an ethnically diverse country like China is a huge research project, and an achievement that anthropological and dermatoglyphic scholars in the country could once only dream of. However, through the endeavors of scientists in China over the last 30 years, the dream has become reality. This paper reports the results of a comprehensive analysis of dermatoglyphics from all ethnic groups in China.

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Article Synopsis
  • Fibroblast growth factors (FGFs) are crucial for various developmental processes, and mutations in FGF signaling can lead to skeletal issues and cancers.
  • A specific missense mutation (Ser99Asp) in the FGF9 gene was identified in a large Chinese family associated with multiple synostoses syndrome (SYNS).
  • The mutation impairs FGF9's ability to bind to its receptor, leading to reduced signaling activity, which adversely affects chondrocyte function and promotes bone cell differentiation, highlighting FGF9's critical role in joint development.
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Amis is the largest aboriginal population in Taiwan. The previous dermatoglyphic studies of the Amis only reported limited data. In this study, we collected and analyzed the dermatoglyphs of 200 Amis individuals, and we reported a wide range of dermatoglyphic variables including total finger ridge count, a-b ridge count, atd angle, axial triradius percent distance, and frequencies of fingerprint pattern, palmar thenar pattern, palmar interdigital pattern, and simian line.

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By the 1970s, a number of dermatoglyphic studies of Taiwan aborigines (Gaoshan nationality) had been published, however in each only a few dermatoglyphic variables were addressed. Since that time, little new research has been conducted. In this study, we collected and analyzed the dermatoglyphs of 100 individuals of Kavalan, a Taiwan aboriginal population, and we reported a wide range of dermatoglyphic variables including total finger ridge count (TFRC), a-b total ridge count (a-b RC), atd angle and axial triradius percent distance (tPD), and frequencies of fingerprint pattern, palmar thenar pattern, palmar interdigital pattern, palmar hypothenar pattern, and simian line.

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