Alpha-Mangostin Ameliorates Bleomycin-Induced Pulmonary Fibrosis in Mice Partly Through Activating Adenosine 5'-Monophosphate-Activated Protein Kinase.

Pulmonary fibrosis (PF) is a devastating interstitial lung disease and characterized by an abnormal accumulation of extracellular matrix (ECM). Nintedanib (NDN) and pirfenidone are two approved therapies for PF, but their potential side-effects have been reported. Recently, the use of natural supplements for PF is attracting attention.

Comparison of 3 Treatment Methods for Distal Tibial Fractures: A Network Meta-Analysis.

BACKGROUND The choice of optimal internal fixation device for distal tibial fractures remains controversial. The purpose of our study was to evaluate the effectiveness and safety of open reduction and internal fixation, minimally invasive percutaneous osteosynthesis, and intramedullary nailing of distal tibial fractures in adults using network meta-analysis of data from clinical trials. MATERIAL AND METHODS The studies were abstracted from MEDLINE, EMBASE, CNKI, and the Cochrane Central Register of Controlled Trials.

Wedelolactone Attenuates Pulmonary Fibrosis Partly Through Activating AMPK and Regulating Raf-MAPKs Signaling Pathway.

Pulmonary fibrosis is common in a variety of inflammatory lung diseases, there is currently no effective clinical drug treatment. It has been reported that the ethanol extract of . can improve the lung collagen deposition and fibrosis pathology induced by bleomycin (BLM) in mice.

[Preliminary analysis of the effect of different administration routes of tranexamic acid on blood loss after total hip arthroplasty for female femur neck fractures].

Objective: To study curative effect of different administration routes of tranexamic acid (TXA) on blood loss of elderly female patients with femoral neck fracture in total hip arthroplasty.

Methods: From December 2015 to January 2018, 77 elderly women with femoral neck fractures undergoing total hip replacement were divided into four groups: group A, group B, group C, and group D. The group A (intravenous medication group) included 21 patients with an average age of (77.

[Effects of nano-zirconium hydroxide coating on resin bonding of 10-methacryloxy decyldihydrogen phosphate-conditioned zirconia].

Objective: This study evaluated the influence of alkaline coating of nano-zirconium hydroxide on resin bonding of 10-methacryloxy decyldihydrogen phosphate (MDP)-conditioned zirconia.

Methods: A total of 140 yttria-stabilized tetragonal zirconia polycrystals (Y-TZP) plates were prepared and sandblasted with alumina particles, and then subjected to different surface treatment. Resin bonding specimens were prepared with a MDP-free resin cement and tested for shear bond strength (SBS).

[The effect of glass fiber volume content on the flexural property of fiber-reinforced composite].

Purpose: To investigate the effect of glass fiber volume content on the flexural property of fiber-reinforced composite． METHODS： The specimens of composite were fabricated with 4 different glass fiber volume contents by changing roving winded number of strands dipped in resin matrix, and the mechanical properties were tested by 3-point flexural test in order to determine the optimal fiber volume content. The data was analyzed statistically with SPSS20.0 software package.

[Case-control study on effects of vacuum drainage on perioperative blood loss after total hip arthroplasty for the treatment of femoral neck fractures].

Objective: To compare postoperative blood loss under different negative pressures of drainage after total hip arthroplasty for the treatment of femoral neck fractures.

Methods: From January 1st to December 30th 2013, 74 patients with femoral neck fractures treated with total hip arthroplasty were randomly divided into two groups: high negative pressure drainage group and low negative pressure drainage group. In high negative pressure drainage group, there were 34 cases including 10 males and 24 females, with a mean age of (75.

[Improving bonding of zirconia through deposition of silica layer via collosol-gelatin process, the roles of NaHCO3].

Objective: To evaluate the effects of NaHCO3 on gelation of silica sols and shear bond strength of silica coated zirconia via collosol-gelatin (Sol-Gel) process.

Methods: The gelation time of silica sols after being mixed with 1%, 3%, 5%, 7%, 10% concentrations of NaHCO3 was recorded. The one got the shortest gelation time was used for the following tests.

[Evaluating on recognition impairment after traumatic brain injury with WCST].

Objective: To explore the value of Wisconsin Card Sorting Test (WCST) in evaluating the recognition impairment after traumatic brain injury (TB1).

Methods: WCST and Wechsler Adult Intelligence Scale Revised in China (WAIS-RC) were adopted to assess the cognitive function in 186 patients with brain injury (experimental group) and 180 healthy volunteers (control group), respectively. The cognition between the experimental group and the control group was compared.

[Analysis of concurrent intravertebral vacuum sign in thoracolumbar fractures after posterior internal fixation].

Objective: To investigate the importance of TLICS classification to surgical options of thoracolumbar fractures by analyzing the cause of intravertebral vacuum sign, vertebral collapse and vertebral pseudarthrosis.

Methods: From January 2006 to December 2010, the clinical data about 15 patients with postoperative complications by thoracolumbar fracture after posterior internal fixation were retrospectively analyzed. There were 9 males and 6 females, ranging in age from 18 to 75 years, with an average of 54.

Effect of cilostazol on cerebral arteries in secondary prevention of ischemic stroke.

Objective: To compare the effects of cilostazol on cerebral arteries and cerebrovascular blood flow in secondary prevention of ischemic stroke, with those of aspirin.

Methods: Sixty-eight patients who had ischemic stroke during the recent 1-6 months were recruited and randomized into cilostazol or aspirin group. Cerebrovascular condition was assessed by magnetic resonance angiography (MRA) and transcranial doppler ultrasonography (TCD) at the beginning of the study and after 12-month medication.

[Color property evaluation of 7 kinds of resin-based composite products].

Objective: To investigate the color stability and opacity of seven resin-based composite products after ultraviolet irradiation.

Methods: Seven kinds of light-cured resin-based composite products (Aelite Flo, Filtek Z350 Flowable, Clearfil AP-X, Dyract AP, Z100, Durafill VS, Filtek Z350 Universal) were tested in the study (five for each group). Changes in color and opacity of test samples were determined before and after 8, 16 and 24 h ultraviolet irradiation using the CIE 1976 L*a*b* system and CIE 1931 XYZ system by a colorimeter.

[Effects of ultraviolet aging on color and translucency of composite resin cements].

Objective: To investigate the color stability and translucency of four composite resin cements after ultraviolet (UV) aging.

Methods: 20 composite resin cement disks for four groups (Group A, dual cured, Biscem; Group B, light cured, Choice; Group C, self cured, PermaCem; Group D, self cured, RelyX Aplicap) were prepared according to their manufacture recommendation. Changes in color and translucency of test samples were determined before and after UV aging for 8, 16 and 24 hour using the CIE L* a* b* system by a colorimeter.

[Effect of nano-silica coating prepared by different concentration silica sol on shear bond strength of alumina ceramic].

Objective: To evaluate the effect of nano-silica coating prepared by different concentration silica sol on shear bond strength between alumina ceramic and resin cement.

Methods: Silica coating was prepared with colloidal silica sol on alumina ceramic surface that was treated with air particle abrasion. Infrared spectrum (IR), scanning electron microscopy (SEM) and energy dispersive spectrometer (EDS) were used to analyze the silica coating.

[Surface modification of dental alumina ceramic with silica coating].

Objective: To make silica coating through sol-gel process, and to evaluate the wettability of dental alumina ceramic with or without coating.

Methods: Silica coating was prepared with colloidal silica sol on In-Ceram alumina ceramic surface which had been treated with air particle abrasion. Coating gel after heat treatment was observed with atomic force microscope (AFM), and was analyzed by infrared spectrum (IR) with gel without sintered as control.