Publications by authors named "Hai-Deng Yang"
Article Synopsis
- Endoscopy is crucial for detecting esophageal squamous cell carcinoma and precancerous lesions, but improving detection rates is still a challenge.
- A new system using deep convolutional neural networks (CNNs) was developed and tested to enhance the detection of high-risk esophageal lesions (HrELs) during endoscopy, and showed significant improvement in detection rates.
- In a clinical trial with over 3,100 patients, the CNN-assisted endoscopy group had a HrEL detection rate of 1.8%, compared to 0.9% in the control group, demonstrating greater sensitivity, specificity, and accuracy without any adverse events.
ARL9 is upregulated and serves as a biomarker for a poor prognosis in colon adenocarcinoma.
BMC Gastroenterol
February 2023
Article Synopsis
- ARL9 is a newly identified gene associated with colon adenocarcinoma, with higher mRNA expression found in cancerous tissues compared to normal adjacent tissues.
- Elevated levels of ARL9 mRNA are linked to a poorer 5-year survival rate for patients, making it a significant prognostic factor independent of other clinical characteristics like sex and tumor stage.
- Gene set enrichment analysis indicates that ARL9 may influence key pathways related to tumor progression, impacting cell adhesion and metabolism within the cancer environment.
Effectiveness and safety of endoscopic resection for duodenal gastrointestinal stromal tumors: A single center analysis.
World J Gastrointest Endosc
November 2022
Background: Endoscopic resection for duodenal gastrointestinal stromal tumors (GISTs) is still considered a great challenge with a high risk of complications, including perforation, bleeding, tumor rupture, and residual tumor.
Aim: To assess the effectiveness and safety of endoscopic resection for duodenal GISTs.
Methods: Between January 2010 and January 2022, 11 patients with duodenal GISTs were treated with endoscopic resection.