Exploring flat-band properties in two-dimensional MQX compounds.

We present a computational study of the MQX family of two-dimensional compounds, focusing specifically on their flat-band properties. We use a high-throughput search methodology, accelerated by machine learning, to explore the vast chemical space spawned by this family. In this way, we identify numerous stable 2D compounds within the MQX family.

Ruddlesden-Popper Oxyfluorides LaNiCuOF (0 ≤ ≤ 1): Impact of the Ni/Cu Ratio on the Thermal Stability and Magnetic Properties.

Ruddlesden-Popper oxyfluorides of the substitution series LaNiCuOF (0 ≤ ≤ 1) were obtained by topochemical fluorination with polyvinylidene fluoride (PVDF) of oxide precursors LaNiCuO. The thermal stability and the temperature-dependent unit cell evolution of the oxyfluorides were investigated by high-temperature XRD measurements. The oxyfluoride with = 0.

Ruddlesden-Popper Oxyfluorides LaNiCuOF (0 ≤ ≤ 1): Impact of the Ni/Cu Ratio on the Structure.

Ruddlesden-Popper oxyfluorides LaNiCuOF (0 ≤ ≤ 1) were obtained by topochemical reaction of oxide precursors LaNiCuO, prepared by citrate-based soft chemistry synthesis, with polyvinylidene fluoride (PVDF) as the fluorine source. Systematic changes of the crystal structure in the oxide as well as the oxyfluoride substitution series were investigated. For 0.

Two-Dimensional Noble Metal Chalcogenides in the Frustrated Snub-Square Lattice.

We study two-dimensional noble metal chalcogenides, with compositions {Cu, Ag, Au}{S, Se, Te}, crystallizing in a snub-square lattice. This is a semiregular two-dimensional tesselation formed by triangles and squares that exhibits geometrical frustration. We use for comparison a square lattice, from which the snub-square tiling can be derived by a simple rotation of the squares.

Function and biomedical implications of exosomal microRNAs delivered by parenchymal and nonparenchymal cells in hepatocellular carcinoma.

Small extracellular vesicles (exosomes) are important components of the tumor microenvironment. They are small membrane-bound vesicles derived from almost all cell types and play an important role in intercellular communication. Exosomes transmit biological molecules obtained from parent cells, such as proteins, lipids, and nucleic acids, and are involved in cancer development.

Machine-Learning-Assisted Determination of the Global Zero-Temperature Phase Diagram of Materials.

Crystal-graph attention neural networks have emerged recently as remarkable tools for the prediction of thermodynamic stability. The efficacy of their learning capabilities and their reliability is however subject to the quantity and quality of the data they are fed. Previous networks exhibit strong biases due to the inhomogeneity of the training data.

Dysregulation of EZH2/miR-138-5p Axis Contributes to Radiosensitivity in Hepatocellular Carcinoma Cell by Downregulating Hypoxia-Inducible Factor 1 Alpha (HIF-1).

Enhancer of zeste homolog 2 (EZH2) is a histone methyltransferase involved in cell proliferation, invasion, angiogenesis, and metastasis in various cancers, including hepatocellular carcinoma (HCC). However, the role and molecular mechanisms of EZH2 in HCC radiosensitivity remain unclear. Here, we show that EZH2 is upregulated in HCC cells and the aberrantly overexpressed EZH2 is associated with the poor prognosis of HCC patients.

A dataset of 175k stable and metastable materials calculated with the PBEsol and SCAN functionals.

In the past decade we have witnessed the appearance of large databases of calculated material properties. These are most often obtained with the Perdew-Burke-Ernzerhof (PBE) functional of density-functional theory, a well established and reliable technique that is by now the standard in materials science. However, there have been recent theoretical developments that allow for increased accuracy in the calculations.

Structure, Magnetism, and Thermal Stability of LaNiOF: A Ruddlesden-Popper Oxyfluoride Crystallizing in Space Group 4/.

We report on the new Ruddlesden-Popper (RP) oxyfluoride LaNiOF containing an unprecedented high amount of fluorine and Ni. This oxyfluoride was prepared by topochemical low-temperature fluorination of LaNiO, which was obtained by a soft chemistry synthesis, with poly(vinylidene difluoride) (PVDF) as fluorinating agent. LaNiOF is the first = 1 RP compound crystallizing in the tetragonal space group 4/ ( = 5.

Isolation and Characterization of Nocardia Species from Pulmonary Nocardiosis in a Tertiary Hospital in China.

This study aimed to investigate the clinical features, distribution, and antimicrobial susceptibility of Nocardia species isolated from pulmonary nocardiosis cases in a tertiary hospital in China. The species were collected from January 1, 2018, to May 31, 2019, and identified using Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry or polymerase chain reaction. Antimicrobial susceptibility testing was performed using the broth microdilution method.

Atomically Thin Pythagorean Tilings in Two Dimensions.

We perform a theoretical study of an atomically thin, two-dimensional layer obtained by positioning atoms at the vertices of the classical Pythagorean tiling. This leads to an unusual geometrical pattern that is only stable for the three halogens Cl, Br, and I. In this Pythagorean structure, halogen atoms are arranged in strongly bound diatomic units that bind together by weaker electrostatic bonds.

Characterization of carbapenem-resistant hypervirulent Acinetobacter baumannii strains isolated from hospitalized patients in the mid-south region of China.

Background: Acinetobacter baumannii has traditionally been considered an opportunistic pathogen with low virulence. In this study, we characterized the carbapenem-resistant hypervirulent A. baumannii (CR-hvAB) stains isolated from our hospital in mid-south region of China.

Overexpression of Platelet-Derived Growth Factor Receptor Α Mutants Prevents Liver Regeneration and Chemically Induced Hepatocarcinogenesis via Inhibition of MET and EGFR.

Platelet-derived growth receptor α (PDGFRα) is a key factor in many pathophysiological processes. The expression level of PDGFRα is significantly elevated in the early stage of liver development and maintained at a lower level in adult normal livers. In this study, we constructed a liver-specific PDGFRαD842 mutant transgenic (TG) mice model to explore the effect of continuous activation of PDGFRα on liver regeneration and hepatocarcinogenesis.

Emergence of an NDM-5-Producing Sequence Type 410 Clone in Infants in a Children's Hospital in China.

Purpose: Outbreaks of infection due to carbapenem-resistant (CRE), including New Delhi metallo-β-lactamase (NDM)-producing , have been increasingly reported worldwide, primarily in adults and rarely in children. The goal of this study was to characterize an outbreak of infection caused by NDM-5-producing in a children's hospital in China.

Methods: A total of 86 CRE isolates were collected from 85 hospitalized children between June 2017 and May 2018.

Isolation and characterization of a sequence type 25 carbapenem-resistant hypervirulent Klebsiella pneumoniae from the mid-south region of China.

Background: The molecular characterization of carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP) isolates is not well studied. Our goal was to investigate the molecular epidemiology of CR-hvKP strains that were isolated from a Chinese hospital.

Results: All clinical carbapenem-resistant K.

Co-existence of blaOXA-23 and blaVIM in carbapenem-resistant Acinetobacter baumannii isolates belonging to global complex 2 in a Chinese teaching hospital.

Background: Carbapenem-resistant Acinetobacter baumannii (CRAB) have been a challenging concern of health-care associated infections. The aim of the current study was to investigate the molecular epidemiology and clonal dissemination of CRAB isolates in a Chinese teaching hospital.

Methods: Non-duplicate clinical A.

An Outbreak of Infections Caused by a Klebsiella pneumoniae ST11 Clone Coproducing Klebsiella pneumoniae Carbapenemase-2 and RmtB in a Chinese Teaching Hospital.

Background: Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae bacteria, which cause serious disease outbreaks worldwide, was rarely detected in Xiangya Hospital, prior to an outbreak that occurred from August 4, 2014, to March 17, 2015. The aim of this study was to analyze the epidemiology and molecular characteristics of the K.

miR-21 improves the neurological outcome after traumatic brain injury in rats.

The expression levels of microRNAs (miRNAs) including miR-21, have been reported to change in response to traumatic brain injury (TBI), suggesting that they may influence the pathophysiological process in brain injury. To analyze the potential effect of miR-21 on neurological function after TBI, we employed the fluid percussion injury rat model and manipulated the expression level of miR-21 in brain using intracerebroventricular infusion of miR-21 agomir or antagomir. We found that upregulation of miR-21 level in brain conferred a better neurological outcome after TBI by improving long-term neurological function, alleviating brain edema and decreasing lesion volume.

Clinical and histopathological analysis of 66 cases with cardiac myxoma.

Background And Purpose: Cardiac myxoma is a major primary heart tumor which often causes unexpected symptoms or sudden death. This present study was designed to investigate its clinical pathological features and biological behavior.

Methods: A retrospective analysis of the clinical pathologic and immunohistochemical features of 66 cases with cardiac myxoma was conducted.

[The study of the inducing donor specific immunological tolerance by GM-CSF and TGF-βtreated donor's marrow cell].

Aim: to observe whether the donor's marrow (BM) cells treated by GM-CSF and TGF-β in vitro were beneficial in inducing specific hypoergia to donor's lymphocyte in recipient.

Methods: donor's marrow cell were cultured with GM-CSF and TGF-β in vitro and its maturities were tested by treating with LPS. BALB/c mice were divided into three groups and received treatment as following: (1) BM pretreatment group: donor's BM cell mentioned above were injected into caudal vein with 10(5); cell each mouse; (2) donor's splenocyte group: C57BL/6 mouse's splenocyte were injected through caudal vein with 10(5); cell each mouse; (3) Negative control group: PBS with the same volume were injected through caudal vein.