Decreased DC-SIGNR expression in hepatocellular carcinoma predicts poor patient prognosis.

Dendritic cell-specific intercellular adhesion molecule-grabbing non-integrin-related protein (DC-SIGNR) is a transmembrane receptor primarily involved in pathogen recognition by the innate immune system, with particular importance for viral recognition. DC-SIGNR may also be associated with tumorigenesis. The aim of the present study was to investigate the association between DC-SIGNR expression, development of hepatocellular carcinoma (HCC), and clinicopathological features.

Decreased CRHBP expression is predictive of poor prognosis in patients with hepatocellular carcinoma.

Corticotropin releasing hormone binding protein (CRHBP) mediates the reaction between corticotropin releasing hormone (CRH) and corticotropin releasing hormone receptors (CRHRs). It is expressed in a number of organs, and the expression of CRHBP is associated with tumorigenesis and cancer progression. The aim of the present study was to investigate CRHBP expression levels in hepatocellular carcinoma (HCC) and its association with patient clinicopathological characteristics as well as prognosis.

Aggregation-induced emission enhancement of polycyclic aromatic alkaloid derivatives and the crucial role of excited-state proton-transfer.

Aggregation-induced emission enhancement (AIEE) phenomenon is observed in the polycyclic aromatic alkaloid derivatives due to the configuration changes in the excited state, which is attributed to intramolecular proton-transfer and the formation of a new structure of enol form.