Publications by authors named "Hai Yang"

,-Dimethylformamide (DMF) is a widely used solvent, and its green and low-carbon synthesis methods are in high demand. Herein, we report a new approach for DMF synthesis using a continuous flow reaction system with a fixed-bed reactor and a ZnO-TiO solid solution catalyst. This catalyst effectively utilizes CO, H, and dimethylamine (DMA) as feedstocks, demonstrating performance with 99% DMF selectivity and single-pass DMA conversion approaching thermodynamic equilibrium.

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Objective: This study aims to conduct a systematic review and network meta-analysis to evaluate the efficacy and safety of specific corticosteroids, including but not limited to hydrocortisone, methylprednisolone, prednisolone, and dexamethasone, in the treatment of severe community-acquired pneumonia (SCAP). Efficacy will be assessed using specific outcomes, such as 30-day mortality and the requirement for mechanical ventilation. Safety evaluations will include adverse events like gastrointestinal bleeding and healthcare-associated infections.

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Li-rich Mn-based layered oxides (LRMOs) are regarded as the leading cathode materials to overcome the bottleneck of higher energy density. Nevertheless, they encounter significant challenges, including voltage decay, poor cycle stability, and inferior rate performance, primarily due to irreversible oxygen release, transition metal dissolution, and sluggish transport kinetics. Moreover, traditionally single modification strategies do not adequately address these issues.

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Pyridoxal 5'-phosphate (PLP)-dependent enzymes catalyze a diverse array of biochemical transformations, making them invaluable biocatalytic tools for the synthesis of complex bioactive compounds. Here, we report the biochemical characterization of LolC, a PLP-dependent γ-synthase involved in the biosynthesis of loline alkaloids. LolC catalyzes the formation of a Cγ-N bond between -acetyl--homoserine (OAH) and l-proline, generating a diamino diacid intermediate.

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The development of efficient and durable electrocatalysts for the acidic oxygen evolution reaction (OER) is essential for advancing renewable hydrogen energy technology. However, the slow deprotonation kinetics of oxo-intermediates, involving the four proton-coupled electron steps, hinder the acidic OER progress. Herein, a RuTiO solid solution electrocatalyst is investigated, which features bridged oxygen (O) sites that act as proton acceptors, accelerating the deprotonation of oxo-intermediates.

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  • Diploid lines from tetraploid potato cultivars were hybridized with wild diploid species, resulting in fertile offsprings, with the pollen of Group Phureja (e.g., IVP101) commonly used to facilitate this hybridization.
  • The study created a hybrid population between the tetraploid cultivar Cooperation 88 (C88) and IVP101, analyzing 43 diploid offsprings for genetic composition using flow cytometry and ploidyNGS.
  • Findings showed that all diploids shared chloroplast sequences from C88, indicating no paternal chloroplast inheritance, while SNP analysis revealed that nuclear genes from the inducer (IVP101) contributed to traits like purple stems in the offspr
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To gain an in-depth understanding of the process of myricetin (MY) inhibiting the generation of O from Xanthine Oxidase (XOD) at a novel perspective, the inhibiting pathway is necessary to be re-elaborated through inhibitory type, thermodynamic analysis and molecular simulation. The results demonstrated that MY is indeed a potent inhibiting agent for O producing from XOD, with the maximum value of 33.78 % in the inhibition of O.

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  • Photodynamic therapy (PDT) is effective in killing tumor cells and provoking immune responses, but its effectiveness is often limited by antioxidant systems like glutathione (GSH) and thioredoxin (Trx).
  • A new nanomedicine (PtHPs) was developed that combines a photosensitizer (PPa) and a cisplatin prodrug (Pt(IV)) using hydroxyethyl starch (HES) to inhibit these antioxidant systems and enhance PDT's effectiveness.
  • In tests, PtHPs demonstrated improved tumor-killing capabilities, increased reactive oxygen species (ROS) production, and promoted immune responses, leading to significant tumor suppression in various models with good safety outcomes.
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Background: Whether prehospital blood pressure control improves outcomes among patients with acute ischemic stroke is uncertain. This systematic review and meta-analysis aimed to evaluate the effect of prehospital blood pressure reduction treatment in patients with ischemic stroke.

Methods: We searched PubMed, Embase, and the Cochrane Central Register of Controlled Trials for randomized controlled trials that compared prehospital blood pressure reduction treatment with usual treatment or no treatment in patients with stroke.

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Potassium metal batteries (PMBs), with high energy density and low cost, are considered a promising option for grid-scale energy storage systems. However, challenges such as the uneven nucleation of K and instability of the solid electrolyte interphase (SEI) layer result in dendrite growth and poor cyclic performance, limiting practical application. To address them, constructing an artificial interface layer with rich defects can enhance the potassium affinity and promote the uniform nucleation of potassium, yet this can also catalyze electrolyte to decompose, leading to unstable SEI formation and poor cycle stability.

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  • Soil dielectric sensors are essential for measuring real-time soil moisture, but their accuracy is affected by soluble salts in the soil.
  • A study tested eight popular sensors across various salinity levels, finding that most overestimated soil moisture, particularly at higher salinities, while the EC-5 sensor remained accurate.
  • The results suggest that for soil salinity levels greater than 1.0 dS·m, calibrated sensors like TDR series and EC-5 are the best options to ensure accurate soil moisture readings.
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(-)-Swainsonine is a polyhydroxylated indolizidine alkaloid with potent inhibitory activity against α-D-mannosidases. In this work, we successfully reconstituted swainsonine biosynthetic pathway both in vivo and in vitro. Our study unveiled a surprising epimerization mechanism involving an imine reductase (SwnN) and two non-heme iron and α-ketoglutarate-dependent oxygenases (SwnH2 and SwnH1).

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  • Traditional drilling fluid measurements are slow and not effective in variable temperature situations, leading to errors in monitoring fluid performance.
  • A new calibration model using support vector machines (SVM) is proposed to improve the accuracy and stability of these measurements, along with a real-time monitoring platform.
  • Experimental results show that the proposed method significantly reduces prediction errors for key rheological parameters, achieving high accuracy with a coefficient of determination over 0.95.
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  • The study investigates the benefits of robot-assisted unilateral biportal endoscopy (R-ULIF) in lumbar decompression fusion surgery, comparing it to percutaneous endoscopic lumbar decompression and interbody fusion (Endo-LIF).
  • A total of 26 patients were divided into two equal groups, with various factors analyzed including operation time, blood loss, postoperative stay, and effectiveness measured by pain and disability indices.
  • Results showed the R-ULIF group had less fluoroscopy use, reduced blood loss, and shorter hospital stays, with better functional outcomes at 1 and 3 months post-surgery, indicating it may be a superior option for this procedure.
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Purpose: In patients undergoing hemiarthroplasty in the elderly, the choice of the cemented method remains controversial. This meta-analysis was undertaken to compare the impact of cemented vs uncemented on outcomes for hemiarthroplasty in the elderly.

Methods: This study included randomized controlled trials comparing the postoperative effects of cemented vs uncemented in patients with hemiarthroplasty.

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The rotating arc plasma method, based on its unique characteristics, provides a simple, efficient, and catalyst-free approach for graphene material synthesis. This study employs molecular dynamics simulations to theoretically investigate the detailed growth process of graphene at the atomic scale using plasma. During the growth process, different radicals serve as dissociation precursors within the plasma.

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The difference on inhibitory effects of bioflavonoids inhibiting XOD activity assayed by varying test methods cause of us to be further in consideration. The reported test method creating a micro-environment surrounding XOD in the absence of ⋅O , which is seemly different from the assay in vivo. So, the vitro test method for assaying XOD activity is necessary to be improved for selection of potential inhibitors in the presence of ⋅O .

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Objective: Air pollution is a leading public health issue. This study investigated the effect of air quality and pollutants on pulmonary function and inflammation in patients with asthma in Shanghai.

Methods: The study monitored 27 asthma outpatients for a year, collecting data on weather, patient self-management [daily asthma diary, peak expiratory flow (PEF) monitoring, medication usage], spirometry and serum markers.

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  • Photodynamic therapy (PDT) is gaining popularity as a non-invasive cancer treatment, but traditional photosensitizers face challenges due to decreased sensitivity and limited oxygen access.
  • Researchers developed water-soluble aggregation-induced emission luminogens (AIEgens) that emit bright near-infrared light and generate reactive oxygen species (ROS), enhancing therapy effectiveness.
  • By using cucurbit[10]uril to create nanoassemblies, AIEgens can target cancer cells specifically, leading to efficient ROS production and resulting in selective cancer cell destruction while minimizing harm to normal cells.
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An adaptive event-triggered security control method is proposed for networked robotic teleoperation systems subject to time-varying delays and false data injection (FDI) attacks. An event-triggered scheme is designed via the position and velocity signals of the master and slave robots, where the triggering thresholds can change adaptively with the system states. The position and velocity triggered signals and the feedback error between the operator and the environment forces are utilized to detect whether the transmitted signals suffered from FDI attacks.

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Objective: This study aimed to establish a neural cell injury model in vitro by stimulating PC12 cells with lipopolysaccharide (LPS) and to examine the effects of astragaloside IV on key targets using high-throughput sequence technology and bioinformatics analyses.

Methods: PC12 cells in the logarithmic growth phase were treated with LPS at final concentrations of 0.25, 0.

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Background: The association between fibrinogen-to-albumin ratio (FAR) and in-hospital mortality in patients with spontaneous intracerebral hemorrhage (ICH) has been established. However, the association with long-term mortality in spontaneous ICH remains unclear. This study aims to investigate the association between FAR and long-term mortality in these patients.

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The adsorption of 11-nor-9-carboxy-∆-tetrahydrocannabinol (THC-COOH) by the suspended particles in sewage makes it fail to accurately monitor cannabis abuse. In this work, the model sewage sample was prepared through equivalent mixing the sewage from 10 different sewage treatment plants in Guangdong province of China and used as a comprehensive representative for investigating the adsorption and release behavior of THC-COOH on the suspended particles under different temperature and pH. The solid-liquid distribution of THC-COOH in sewage depended strongly on the adsorption and release properties which were susceptible to the temperature and pH, specially adjusting pH to 11.

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Objective: To investigate the findings on lower limb lymphedema using magnetic resonance lymphography (MRL).

Methods: MRL was used to record the lymphatic vessel morphology, distribution of lymphatic vessels, dermal backflow (DBF), and morphology of inguinal lymph nodes in 112 patients (175 affected limbs) with lower limb lymphedema at different clinical stages (according to the International Society of Lymphology staging criteria 2020).

Results: The lymphatic vessel morphology significantly differed at different clinical stages (X =59.

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Synopsis of recent research by authors named "Hai Yang"

  • - Hai Yang's recent research spans various fields including medical science, energy storage, environmental impacts, and materials science, reflecting a diverse portfolio of studies aimed at addressing critical challenges in these areas.
  • - Notable findings include a systematic review indicating the mixed effects of prehospital blood pressure management in ischemic stroke patients and a study on enhancing the performance of potassium metal batteries through innovative artificial interface layers.
  • - Yang's work also highlights the impact of air quality on asthma patients in Shanghai, along with advancements in methodologies for both soil moisture measurement at varying salinity levels and the synthesis of bioactive compounds, showcasing his commitment to improving health and environmental outcomes.*