While the prevalent utilization of plastic products has enabled social advancement, the concomitant microplastics (MPs) pollution presents a serious threat to environmental security and public health. Protists, as regulators of soil microorganisms, are also capable of responding most rapidly to changes in the soil environment. The amelioration mechanisms of biochar in the soil-plant systems polluted by low-density polyethylene microplastics (LDPE-MPs) and the response of protist communities in the soil-plant systems polluted by MPs remain unclear.
View Article and Find Full Text PDFThe primary cause of the accelerated battery failure in aqueous zinc-ion batteries (AZIBs) is the uncontrollable evolution of the zinc metal-electrolyte interface. In the present research on the development of multiadditives to ameliorate interfaces, it is challenging to elucidate the mechanisms of the various components. Additionally, the synergy among additive molecules is frequently disregarded, resulting in the combined efficacy of multiadditives that is unlikely to surpass the sum of each component.
View Article and Find Full Text PDFObjectives: In this retrospective observational multicenter study, we aimed to assess efficacy and mortality between ceftazidime/avibactam (CAZ/AVI) or polymyxin B (PMB)-based regimens for the treatment of Carbapenem-resistant Klebsiella pneumoniae (CRKP) infections, as well as identify potential risk factors.
Methods: A total of 276 CRKP-infected patients were enrolled in our study. Binary logistic and Cox regression analysis with a propensity score-matched (PSM) model were performed to identify risk factors for efficacy and mortality.
Soil microplastics (MPs) have attracted widespread attention recently. Most studies have explored how soil MPs affect the soil's physicochemical parameters, matter circulation, and soil microbial community assembly. Similarly, a key concern in agricultural development has been the use of phosphorus (P) fertiliser, which is essential for plant health and development.
View Article and Find Full Text PDFBiochar as an agricultural soil amendment plays vital roles in mediating methane (CH) and nitrous oxide (NO) emissions in soils. The link between different types of biochar, bulk soil, and rhizosphere microbial communities in relation to CH and NO emissions is being investigated in this study. The rice pot experiment was conducted using biochar at two temperatures (300°C and 500°C) in combination with three biochar levels (0, 2, 10% w/w).
View Article and Find Full Text PDFA photocatalyst-free radical cleavage of α-diazo sulfonium salts has been developed for the first time. The reaction provides an efficient method for the generation of diazomethyl radicals from α-diazosulfonium triflates under photochemical conditions. Utilizing the in situ generated diazomethyl radicals as key intermediate, the coupling cyclization reaction of α-diazosulfonium triflates with α-oxocarboxylic acids or alkynes has been achieved.
View Article and Find Full Text PDFBackground: The COVID-19 pandemic has exerted an unprecedented and universal impact on global health system, resulting in noticeable challenges in traditional chronic disease care, of which diabetes was reported to be most influenced by the reduction in healthcare resources in the pandemic. China has the world's largest diabetes population, and current diabetes management in China is unsatisfactory, particularly in rural areas. Studies in developed countries have demonstrated that physician-pharmacist collaborative clinics are efficient and cost-effective for diabetes management, but little is known if this mode could be adapted in primary hospitals in China.
View Article and Find Full Text PDFPurpose: Carbapenem-resistant organisms (CROs) pose great challenges for clinical treatment. Polymyxin B (PMB) is one of the "last resort" choices of CRO infections. We explored the possible factors affecting PMB efficacy.
View Article and Find Full Text PDFOpen Life Sci
April 2021
TEA domain family members (TEADs) play important roles in tumor progression. Till now, the genomic status of in patients with glioma has not been well investigated. To confirm whether the genomic status of could affect the prognosis of patients with glioma, the copy number variation (CNV), mutation and expression data of glioma cohorts in The Cancer Genome Atlas, Gene Expression Omnibus and Chinese Glioma Genome Atlas were comprehensively analyzed.
View Article and Find Full Text PDFThe association between Glutathione S-transferase Pi 1(GSTP1) genetic polymorphism (rs1695, 313A>G) and cyclophosphamide-induced toxicities has been widely investigated in previous studies, however, the results were inconsistent. This study was performed to further elucidate the association.A comprehensive search was conducted in PubMed, Embase, Web of Science, China National Knowledge Infrastructure, and Wan Fang database up to January 5, 2020.
View Article and Find Full Text PDFBackground: Prior to 2015, clinical consultation was the only clinical service provided by clinical pharmacists in Changsha Second Hospital. Between 2015 and 2017, a train-the-trainer program was implemented to train clinical pharmacists to provide pharmaceutical care and to conduct clinical research. The objective of the study is to examine the impact on the clinical services provided by pharmacists after the implementation of the train-the-trainer program.
View Article and Find Full Text PDFA novel copper-catalyzed [3 + 2] cycloaddition reaction of alkynes with nitrile oxides generated in situ from the coupling reaction of copper carbene and nitroso radical has been developed. The three-component reaction provides a simple and efficient method for the construction of isoxazoles in a highly regioselective manner in a single step. On the basis of the experimental results and density functional theory calculations, a catalytic cycle (Cu-Cu-Cu-Cu) for this cascade cyclization reaction is proposed.
View Article and Find Full Text PDFThe prognostic role of neutrophil-to-lymphocyte ratio (NLR) in bloodstream infection (BSI) deserves further investigation. The NLR values were measured and compared in BSI patients and healthy controls. The receiver operating characteristic of NLR and cut-off values were measured in BSI patients and subgroups.
View Article and Find Full Text PDFHumic acid (HA) and fulvic acid (FA) are dominating humic substances (HS) in soil. In this study, the effects of HA and FA addition (0.2%-1.
View Article and Find Full Text PDFBiochar has the potential to influence methanogenesis which is a key component of global carbon cycling. However, the mechanisms governing biochar's influence on methanogenesis is not well understood, especially its effects on interspecies relationships between methanogens and anaerobic bacteria (e.g.
View Article and Find Full Text PDFArsenic (As) contamination is a global problem. Straw incorporation is widely performed in As contaminated paddy fields. To understand how straw and straw biochar incorporation affect As transformation and translocation in the soil-microbe-rice system, a pot experiment was carried out with different dosages of rice straw and straw biochar application.
View Article and Find Full Text PDFEnviron Sci Technol
February 2018
Organic matter (OM), and dissolved organic matter (DOM), have a major influence upon biogeochemical processes; most significantly, the carbon cycle. To date, very few studies have examined the spatial heterogeneity of DOM in paddy soils. Thus, very little is known about the DOM molecular profiles and the key environmental factors that underpin DOM molecular chemodiversity in paddy soils.
View Article and Find Full Text PDFAlkaline stress (high pH) severely damages root cells, and consequently, inhibits rice ( L.) seedling growth. In this study, we demonstrate the accumulation of reactive oxygen species (ROS) in root cells under alkaline stress.
View Article and Find Full Text PDFIn this work, the lightweight and scalable organic macromolecule graphitic carbon nitride (g-C3N4) with enriched polysulfide adsorption sites of pyridinic-N was introduced to achieve the effective functionalization of separator at the molecular level. This simple method overcomes the difficulty of low doping content as well as the existence of an uncontrolled form of nitrogen heteroatom in the final product. Besides the conventional pyridinic-N-Li bond formed in the vacancies of g-C3N4, the C-S bond was interestingly observed between g-C3N4 and Li2S, which endowed g-C3N4 with an inherent adsorption capacity for polysulfides.
View Article and Find Full Text PDFSteviol glycosides, extracted from the leaves of Stevia rebaudiana (Bert) Bertoni, are calorie-free sugar substitute of natural origin with intensely sweet (Boileau et al., 2012). Stevioside and rebaudioside A are the two main kinds of the diterpenic glycosides.
View Article and Find Full Text PDFSeveral studies demonstrate that estradiol can prevent arterial calcification. However, little is known regarding the effect of puerarin, a phytoestrogen extracted from Radix Puerariae, on arterial calcification. The aim of the present study was to determine whether puerarin reduced osteoblastic differentiation of calcifying vascular smooth muscle cells (CVSMCs).
View Article and Find Full Text PDFThe effect of citric acid (CA) and ethylene diamine tetraacetic acid (EDTA) on the growth, anatomical structure, physiological responses and lead (Pb) accumulation of Iris lactea var. chinensis seedling growing in Pb mine tailings for 30 days were studied. Results showed that the dry weights (DW) of roots decreased significantly under both levels of CA.
View Article and Find Full Text PDFEarly findings propose that impaired neurotransmission in the brain plays a key role in the pathophysiology of schizophrenia. Recent advances in understanding its multiple etiologies and pathogenetic mechanisms provide more speculative hypotheses focused on even broader somatic systems. Using a targeted tandem mass spectrometry (MS/MS)-based metabolomic platform, we compared metabolic signatures consisting of monoamine and amino acid neurotransmitter (NT) metabolites in plasma/urine simultaneously between first-episode neuroleptic-naïve schizophrenia patients (FENNS) and healthy controls before and after a 6-week risperidone monotherapy, which suggest that the patient NT profiles are restoring during treatment.
View Article and Find Full Text PDFBased on the 1961-2009 weather data from 21 meteorological stations in Ningxia, this paper analyzed the spatiotemporal variation trend of regional agricultural climate resources in Ningxia, Northwest China. In 1961-2009, the air temperature in Ningxia increased gradually from south to north, with the mean annual temperature increased by 0.4 degrees C x (10 a)(-1) , while the annual precipitation in most regions decreased gradually, with a decrement 4.
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