[Construction of Panax ginseng root yeast library and screening of interacting proteins of PgD14 and Pgpht2-1].

To construct a high-quality Panax ginseng cDNA library, transcription factors binding to the P. ginseng PgD14 gene promoter were screened by yeast one-hybrid, and proteins interacting with the P. ginseng Pgpht2-1 gene-encoded protein were screened by yeast two-hybrid.

[Study on differences in metabolism and transcription of ginseng seeds after morphological post ripening by space flight].

To explore the difference in metabolism and transcription between seeds experiencing space flight and ground seeds after morphological post ripening, this study utilized ginseng seeds experiencing space flight and ground seeds as materials. Metabolomics and transcriptomics analyses were conducted using ultra-high performance liquid chromatography-mass spectrometry(UPLC-MS) and high-throughput transcriptome sequencing(RNA-seq) technologies, so as to identify differential terpenoid metabolites, differential endogenous hormones, and differentially expressed genes. The results showed that through metabolomics analysis, a total of 22 differential terpenoid metabolites were identified in the experimental and control groups, including chikusetsusaponin FK_7, ginsenoside F_2, ginseno-side K, majoroside R_1, ginsenoside Re_5, 12-hydroxyabietic acid, etc; through transcriptomics analysis, 15 differential terpenoid metabolism-related differentially expressed genes were identified in the experimental and control groups, including FCase, AACT, PMK, etc, and these genes were integrated into the pathway based on the MEP and MVA.

Molecular Heterogeneous Photocatalysts for Visible-Light-Driven CO Reduction.

Photoreduction of CO to high-value chemical fuels presents an effective strategy to reduce reliance on fossil fuels and mitigate climate change. The development of a photocatalyst characterized by superior activity, high selectivity, and good stability is a critical issue for PCR. Molecular heterogeneous photocatalytic systems integrate the advantages of both homogeneous and heterogeneous catalysts, creating a synergistic enhancement effect that increases photocatalytic performance.

Stand-alone transarterial flow diversion for treatment of carotid cavernous fistulas.

Objective: Carotid-cavernous fistulas (CCFs) are rare arteriovenous communications allowing blood to flow from the carotid artery into the cavernous sinus. Although currently coil and/or liquid embolization remain the preferred treatment methods for CCFs, flow diverters (FD) stents represent a viable alternative to traditional embolization techniques. This study explores both the technical aspects and rationale behind using FD stents as a stand-alone treatment approach for CCFs.

Pore-Scale Simulation of Deep Shale Gas Flow Considering the Dual-Site Langmuir Adsorption Model Based on the Pore Network Model.

As a key resource in the oil and gas sector, shale gas development profoundly influences the advancement of the global energy industry. Deep shale gas reservoirs, typically found at depths exceeding 3500 m, represent a significant portion of total shale gas reserves. Currently, pore network models primarily simulate middle and shallow shale gas, insufficiently addressing the unique challenges posed by high-temperature and high-pressure conditions in deep shale gas formations.

A Novel Method for Early Warning and Quantitative Evaluation of Liquid Loading in Gas Wellbore Based on Dynamic Production Data: A Case Study of Linxing Tight Gas Field.

Gas wells in Linxing Tight Gas Field are characterized by significant water production, and individual well water production measurement is missing, which pose challenges to predict liquid loading and conduct quantitative evaluations. Moreover, relying solely on flow temperature and pressure testing can be costly and time-consuming. To address these critical issues, we established the prewarning model and quantitative evaluation method for liquid loading.

Cerebrovascular implications of takayasu arteritis: a review.

Purpose: Takayasu arteritis (TA) is a rare, chronic, inflammatory large-vessel vasculitis that affects the aorta and its main branches, including the cerebrovascular system. This review analyzes current knowledge and patient outcomes concerning the cerebrovascular implications of TA.

Methods: A literature search, with publications from 1994 to 2024, identified pertinent studies through PubMed.

Interfacial Rheological Investigation of Modified Silica Nanoparticles with Different Alkyl Chain Lengths at the n-Octane/Water Interface.

The interfacial dilational rheology of silica nanoparticles (NPs) directly reflects the relationship between surface structure and interfacial behaviors in NPs, which has attracted significant attention in various industrial fields. In this work, modified silica nanoparticles (MNPs) with various alkyl chain lengths were synthesized and systematically characterized using Fourier transform infrared spectra, Zeta potential, and water contact angle measurements. It was found that the MNPs were successfully fabricated with similar degrees of modification.

A unique anatomic variant: Left anterior choroidal artery arising proximal to fetal posterior communicating artery.

Anomalous vascular variants pose unique challenges in clinical management, especially in the context of neuroendovascular intervention. We present a case report detailing an extremely rare anatomic variant involving the left anterior choroidal artery, which arises proximal to the fetal posterior communicating artery. Our patient presented with confusion and speech abnormalities following a benzodiazepine overdose.

Delayed cerebrovascular reactivity in individuals with spinal cord injury in the right inferior parietal lobe: a breath-hold functional near-infrared spectroscopy study.

Cerebrovascular reactivity (CVR) reflects the ability of blood vessels to dilate or constrict in response to a vasoactive stimulus, and allows researchers to assess the brain's vascular health. Individuals with spinal cord injury (SCI) are at an increased risk for autonomic dysfunction in addition to cognitive impairments, which have been linked to a decline in CVR; however, there is currently a lack of brain-imaging studies that investigate how CVR is altered after SCI. In this study, we used a breath-holding hypercapnic stimulus and functional near-infrared spectroscopy (fNIRS) to investigate CVR alterations in individuals with SCI (n = 20, 14M, 6F, mean age = 46.

[Interaction between root exudates of medicinal plants and rhizosphere microorganisms and its application in ecological planting of Chinese medicinal materials].

The rhizosphere is an important place for material exchange between medicinal plants and soil. Root exudates are the medium of material and signal exchange between plants and soil and are the key factors in the regulation of rhizosphere microecology. Rhizosphere microorganisms are an important part of the rhizosphere microecology of medicinal plants, and the interaction between root exudates and rhizosphere microorganisms has an important influence on the growth and quality formation of medicinal plants.

Three-Dimensional-Printed Template-Guided Radioactive Seed Brachytherapy via a Submental Approach for Recurrent Base of Tongue and Floor of Mouth Cancer.

Background: This study assessed clinical outcomes of three-dimensional-printed template (3DPT)-guided radioactive seed brachytherapy (RSBT) via a submental approach for recurrent base of tongue and floor of mouth cancer.

Methods: Thirty-one patients with recurrent lingual and floor of mouth squamous cell carcinoma after surgery and radiotherapy were treated with 3DPT-guided RSBT from 2015 to 2022. Seeds were implanted through a submental approach guided by 3DPTs.

Highly Curved Defect Sites: How Curvature Effect Influences Metal-Free Defective Carbon Electrocatalysts.

Topological defects are widely recognized as effective active sites toward a variety of electrochemical reactions. However, the role of defect curvature is still not fully understood. Herein, carbon nanomaterials with rich topological defect sites of tunable curvature is reported.

Coupling Ni Single Atomic Sites with Metallic Aggregates at Adjacent Geometry on Carbon Support for Efficient Hydrogen Peroxide Electrosynthesis.

Single atomic catalysts have shown great potential in efficiently electro-converting O to HO with high selectivity. However, the impact of coordination environment and introduction of extra metallic aggregates on catalytic performance still remains unclear. Herein, first a series of carbon-based catalysts with embedded coupling Ni single atomic sites and corresponding metallic nanoparticles at adjacent geometry is synthesized.

Does Small Aneurysm Size (<10 mm) Predict Complete Occlusion After Flow Diversion? A Surpass Evolve Single-Center Study.

Background: Long-term safety and efficacy outcomes of Surpass Evolve flow diverter (SEFD) in treatment of intracranial aneurysms are lacking. Factors predicting complete aneurysm occlusion are elusive in literature.

Methods: A retrospective review of all consecutive aneurysms treated with SEFD from February 2020 to July 2022, at a single comprehensive stroke center.

Rejuvenating classical brain electrophysiology source localization methods with spatial graph Fourier filters for source extents estimation.

EEG/MEG source imaging (ESI) aims to find the underlying brain sources to explain the observed EEG or MEG measurement. Multiple classical approaches have been proposed to solve the ESI problem based on different neurophysiological assumptions. To support clinical decision-making, it is important to estimate not only the exact location of the source signal but also the extended source activation regions.

Creating a new yellow and blue combination transparent film for C.A. Meyer growth based on orthogonal designs.

C.A. Meyer originates from old-growth forest environments, where the light intensity and spectrum reaching the forest bed are influenced by the canopy and humidity.

Brain activation during the N-back working memory task in individuals with spinal cord injury: a functional near-infrared spectroscopy study.

Cognitive impairments have frequently been reported in individuals with spinal cord injury (SCI) across different domains such as working memory, attention, and executive function. The mechanism of cognitive impairment after SCI is not well understood due to the heterogeneity of SCI sample populations, and may possibly be due to factors such as cardiovascular dysfunction, concomitant traumatic brain injury (TBI), hypoxia, sleep disorders, and body temperature dysregulation. In this study, we implement the Neuropsychiatric Unit Cognitive Assessment Tool (NUCOG) to assess cognitive differences between individuals with SCI and age-matched able-bodied (AB) controls.

Functional outcomes in MRI-guided laser interstitial therapy for temporal lobe epilepsy: a systematic review and meta-analysis.

Objective: The use of MRI-guided laser interstitial thermal therapy (MRgLITT) has emerged as a promising treatment option for patients with drug-resistant temporal lobe epilepsy (TLE). Although the minimally invasive approach holds promise as an effective treatment for achieving seizure freedom, a comprehensive review of its impact on functional outcomes is still warranted. To address this need, this review aims to summarize data pertaining to the functional and neurocognitive outcomes following MRgLITT for TLE.

Brain abscesses following carotid blowout syndrome: a case report.

We report a case of intracranial abscesses development in a patient with head and neck cancer after emergent treatment of carotid blowout syndrome with coil embolization. Our patient is a 60-year-old male who presented with hemoptysis and hematemesis, which raised concerns for impending carotid blowout syndrome. Endovascular occlusion was successfully achieved, and the patient was discharged in stable condition.