Photochemical degradation of iodate by UV/HO process: Kinetics, parameters and enhanced formation of iodo-trihalomethanes during chloramination.

In this paper, it was demonstrated that UV/HO process can not only obviously promote the degradation rate of IO, but also greatly enhance iodo-trihalomethanes (I-THMs) formation in sequential chloramination. UV/HO exhibited much faster IO decomposition than either UV or HO treatment alone due to the contribution of highly reactive species including O, OH and e. The degradation rate of IO was affected by HO dosages, pH, UV intensity as well as the presence of natural organic matter (NOM).

Suppression of Gene by shRNA Augments Gemcitabine Chemosensitization in Pancreatic Adenocarcinoma Cells.

Pancreatic adenocarcinoma has an exceedingly poor prognosis, accounting for five-year survival of less than 5%. Presently, improving the efficacy of pancreatic adenocarcinoma treatment has been the focus of medical researchers worldwide. Recently, it has been suggested that deregulation of interleukin- (IL-) 6 is caused by a key gene involved in the beginning and development of pancreatic adenocarcinoma.

Effect of sterilization methods on cell binding activity of surface-immobilized fibronectin.

The effect of sterilization methods on biological activity of fibronectin on the surface of biomaterials was elaborated in the present study. Sterile protein- modified biomaterials were fabricated by microfilter filtration and UV irradiation, respectively. UV irradiation altered the conformation of surface- adsorbed fibronectin and further affected the attachment, morphology and biological function of endothelial cells.

Construction of a tumor cell-targeting non-viral gene delivery vector with polyethylenimine modified with RGD sequence-containing peptide.

The objective of the present study was to construct a novel type of non-viral gene delivery vector with high delivery efficiency and specific tumor cell-targeting ability. The CP9 peptide (CYGGRGDTP) containing Arg-Gly-Asp sequence was employed to be conjugated onto polyethylenimine (PEI) to act as the role of the targeting moiety. The chemical linker, N-succinimidyl-3-(2-pyridyldithio) propionate, was applied during the synthesis of the vector (CP9-PEI).