Publications by authors named "Hai B Wen"

Dental implant coronal surfaces designed with the primary goal of maintaining crestal bone levels may also promote bacterial adhesion, leading to soft tissue inflammation and peri-implant bone loss. Achieving an optimal surface roughness that minimizes bacterial adhesion while preserving crestal bone is crucial. It is hypothesized that a specific threshold surface roughness value may exist below which, and above which, initial bacterial adhesion does not statistically change.

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To address the hypothesis that the tissue processing methods of solvent dehydration and freeze-drying would differentially affect the physicochemical characteristics of four commercially available bone allografts and the adhesion and differentiation of human bone marrow-derived mesenchymal stromal cells (hBMSCs) on such substrates in vitro. The surface morphology, surface area, and elemental composition of four commercially available cancellous bone allografts were examined using SEM, Brunauer-Emmett-Teller (BET) gas adsorption, and inductively coupled plasma (ICP) analyses. SEM was also employed to compare the allograft surfaces to that of human bone exposed by in vitro osteoclastic resorption.

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Implant topography affects early peri-implant bone healing by changing the osteoconduction rate in the surrounding biological environment. Implant surfaces have been designed to promote faster and stronger bone formation for rapid and stable prosthesis loading. Early peri-implant bone healing has been observed with a sandblasted, acid-etched implant that was chemically modified to be hydrophilic (cmSLA).

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Background: Various connections have been machined to improve the fit between the dental abutment and implant. In vivo, the instability created by imprecisely fitting components can cause soft tissue irritation and bacterial colonization of the implant system. The aim of this study was to quantify abutment stability under in vitro force applications.

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The basal media M199 or MEM was utilized in the classical method of vitro culture of glochidia where 1-5% CO2 was required to maintain stable physiological pH for completion of non-parasitic metamorphosis. The classical method encounters a great challenge to those glochidia which undergo development of visceral tissue but significantly increase in size during metamorphosis. The improved in vitro culture techniques and classical methods were firstly compared for non-parasitic metamorphosis and development of glochidia in pink heelsplitter.

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Aim: This study evaluated new bone formation activities and trabecular bone microarchitecture within the highly porous region of Trabecular Metal™ Dental Implants (TM) and between the threads of Tapered Screw-Vent® Dental Implants (TSV) in fresh canine extraction sockets.

Materials And Methods: Eight partially edentulated dogs received four implants (4.1 mmD × 13 mmL) bilaterally in mandibular fresh extraction sockets (32 TM, 32 TSV implants), and allowed to heal for 2, 4, 8, and 12 weeks.

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Background: Primary stability of a dental implant system is an essential factor to maintain its long-term success. Thus, the objective of this study was to examine whether primary stability is different between threaded and porous dental implant systems placed in artificial bone blocks and human cadaveric mandibular bone.

Materials And Methods: Forty-two threaded and 42 highly porous dental implants were placed in artificial polyurethane bone foams with 7 different thicknesses (3.

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Doubly uniparental inheritance (DUI) of mitochondrial DNA, found only in some bivalve families and characterized by the existence of gender-associated mtDNA lineages that are inherited through males (M-type) or females (F-type), is one of the very few exceptions to the general rule of strict maternal mtDNA inheritance in animals. M-type sequences are often undetected and hence still underrepresented in the GenBank, which hinders the progress of the understanding of the DUI phenomenon. We have sequenced and analyzed the complete M and F mitogenomes of a freshwater mussel, Potamilus alatus.

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The North American pink heelsplitter (Potamilus alatus) differs from most freshwater mussels in China by the ability to secrete an ephemeral byssus during its juvenile stage. In the present study, light microscopy, scanning electron microscopy (SEM), and transmission electron microscopy (TEM) were used to investigate this ephemeral byssal structure, and amino acid composition was analyzed and compared with that of other species. The results revealed that the byssus consists of a long byssal thread and a few adhesive plaques which are randomly set up along the thread and assembled by petioles.

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Purpose: Peri-implantitis is a challenging situation that leads to tissue destruction and eventual implant failure. The purpose of this study was to evaluate and compare, clinically and histologically, the influence of ligature-induced peri-implantitis on two implant designs in a canine extraction socket model.

Materials And Methods: Sixty-four implants (4.

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Background: Resonance frequency analysis (RFA) has been introduced as a noninvasive method to clinically estimate the stability of dental implant systems.

Purpose: The objective of this study was to examine whether implant stability quotient (ISQ) values of RFA can account for mechanical stability of the dental implant system, which is assessed using dynamic mechanical analysis (DMA).

Materials And Methods: Fifty-seven screw-type titanium dental implants were placed in artificial polyurethane foams with seven different thicknesses (3.

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Purpose: This study evaluated the stability and histologic proof of osseoincorporation of Trabecular Metal (TM) dental implants, which feature a tantalum-based porous midsection.

Materials And Methods: A total of 48 TM implants (test group) and Tapered Screw-Vent implants (control group) were immediately placed bilaterally into mandibular extraction sockets in dogs. Resonance frequency analysis was performed at weeks 0, 2, 4, and 12 after implant placement.

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Purpose: To investigate if a dental implant system with a midsection covered by 3-dimensionally porous tantalum material would exhibit stability comparable with a traditional threaded titanium alloy implant system and whether bone would grow into the porous section.

Methods: Three experimental and 3 control implants were placed in the individual mandibles of 8 dogs. Resonance frequency analysis assessed implant stability at 0, 2, 4, 8, and 12 weeks of healing.

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A novel hybrid coating of biomimetic apatite(BAp) and osteocalcin (OC) was prepared by incubating BAp-coated Ti6A14V coupons in an osteocalcin-containing medium. A significant amount (up to 1.0 wt %) of OC was adsorbed by the BAp coating within 3 h of incubation as demonstrated by high-performance liquid chromatography.

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