Publications by authors named "Hahyung Y Kim"
Article Synopsis
- The study explores the development of mammary glands across different species, emphasizing the underutilization of model systems for research.
- Recent advancements in organoid technology have allowed researchers to create 3D mammary gland organoids from eight species of eutherian mammals and the first branched organoid from a marsupial.
- The findings reveal that the ROCK protein plays a key role in the branching of mammary glands, showcasing how organoid models can enhance our understanding of mammary gland biology, evolution, lactation, and breast cancer research.
Evolution experiments in the laboratory have focused heavily on model organisms, often to the exclusion of clinically relevant pathogens. The foodborne bacterial pathogen belongs to a genus whose genomes are small compared to those of its closest genomic relative, the free-living genus , suggesting genome reduction during the course of evolution to host association. In an experiment, serially passaged in rich medium in the laboratory exhibited loss of flagellar motility-an essential function for host colonization.
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