Enhancement of Campylobacter jejuni virulence by serial passage in chicks.

Four isolates of Campylobacter jejuni were studied to determine changes in virulence following six serial passages in chicks. Chicks that received invasive isolates exhibited diarrhea and depressed weight gain. Immature mice were used to assess virulence of the passaged isolates of C.

Viability of Vibrio choierae 01 on Frog Legs under Frozen and Refrigerated Conditions and Low Dose Radiation Treatment.

Frog legs were contaminated with Vibrio cholera 01, Inaba serotype, ElTor biotype. The organism remained viable for more than 28 and 2 d when stored at -20°C and 4°C, respectively. Exposure to a multicurie Cobalt source of 50 and 100 kilorads eliminated V.

A descriptive study of dairy goat predation in Louisiana.

Questionnaires concerning herd size, housing and management, and previous instances of predation were mailed to 124 goat owners in Louisiana. Postcards were mailed over a period of one year on a monthly basis, to the 84 individuals who responded to this questionnaire. Owners were asked to indicate whether they had seen predators on their property and whether any goats were injured or killed by the predators.

Evaluation of the origin of Mycobacterium leprae infections in the wild armadillo, Dasypus novemcinctus.

An enzyme-linked immunosorbent assay (ELISA) using the phenolic glycolipid-1 (PGL-1) antigen of Mycobacterium leprae and cross-reactive antisera specific for human IgM was developed to detect IgM antibodies to M. leprae in the nine-banded armadillo (Dasypus novemcinctus). Statistical definitions for positive and negative interpretations in the ELISA were developed by screening animals recently captured and experimentally inoculated with M.

Airflows after inhalation of terbutaline sulphate aerosol from a 750-ml spacer for four weeks.

Terbutaline sulphate was administered to 40 adult asthmatic patients via an ordinary metered-dose inhaler (MDI) or one connected to a 750-ml spacer in an open, randomized, crossover study. Spirometry was obtained before the start of the study and again after four weeks of treatment with each inhaler. The patients recorded on a diary card the severity of their asthma symptoms and the peak expiratory flow rate (PEFR) in the morning before and after drug administration and in the evening.

Visceral larva migrans: a risk assessment in Baton Rouge, Louisiana.

Visceral larva migrans, VLM, is a disease of young children. Due to lack of awareness of the disease as well as its non-specific symptomology, a survey of the potential risk of acquiring the disease was conducted in the Baton Rouge, Louisiana area. The greatest number of dogs showing positive results to tests for the presence of the eggs of Toxocara canis were those less than one year of age.

Penetration of ampicillin ('Pondocillin') and amoxycillin ('Imacillin') into bronchial secretions.

The penetration of ampicillin and amoxycillin into bronchial secretions was investigated by bronchoscopy in 20 patients suffering from exacerbations of chronic bronchitis. Five patients received 500 mg pivampicillin, 8 received 700 mg pivampicillin and 7 received 500 mg amoxycillin. There were no significant differences between these three treatments in respect of the serum and bronchial secretion concentrations at the time of bronchoscopy, nor were there any significant differences in the peak serum level or total bioavailability of each regimen.

Leprosy in sub-human primates: potential risk for transfer of M. leprae to humans.

Twenty six owned monkeys were examined in Andhra Pradesh, India during the period May-July, 1982. The prevalence rate among humans in daily contact with these monkeys was 98.6/1000.

Prevalence of Mycoplasma and Chlamydia in the nasal flora of dairy calves.

Nasal swabs from dairy calves in 20 selected herds were collected once in each of three sampling periods in one year and cultured for mycoplasmas and chlamydiae. Seventy-seven of 411 calves (19%) and 16 of 20 herds (80%) were positive for mycoplasmas at least once throughout the year, and all of 378 calves sampled from the 20 herds were negative for chlamydiae. Thirty-one percent of the isolates were Mycoplasma bovirhinis; other species isolated less frequently were Mycoplasma bovis, Mycoplasma arginini, and Acholeplasma laidlawaii.

Prevalence of bovine herpesvirus-1, bovine oral diarrhea, parainfluenza-3, bovine adenoviruses-3 and -7, and goat respiratory syncytial viral antibodies in goats.

Sera from healthy goats were collected during October 1979 through October 1980. These sera were tested for bovine herpesvirus-1 (BHV-1), bovine viral diarrhea virus (BVDV), parainfluenza-3 (PI-3) virus, bovine adenoviruses (BAV) -3 and -7, and goat respiratory syncytial virus (GRSV) antibodies by microtitration virus-neutralization test. The number of herds with seropositive goats for each virus were: 5/38 (13.

The need for integrated control programs for zoonoses affecting livestock.

Prior to recognition of etiologic agents of zoonoses (infections transmitted between animals and man), physicians encountered these illnesses in man and veterinarians observed them in animals. As the agents were identified, interspecies relationships (and spread) became evident and control programs evolved without consideration of cost-effectiveness. Today, the public demands efficient use of financial resources.

Interfacing professional training in health maintenance and preventive medicine.

Because of emerging economic realities of the latter half of this century, the practice of preventive medicine, as opposed to curative medicine, is becoming essential in developed and developing countries. This holds true in veterinary medicine as well as in human medicine, and as we become increasingly aware of this fact, we also recognize the increasing interdependence of both fields. To determine the extent to which veterinarians are prepared to deal with this change in emphasis, two surveys have been prepared; one directed to various specialty groups within the profession and the other directed to schools of veterinary medicine.

Development of a health and safety program at the Louisiana State University School of Veterinary Medicine.

An accident prevention and zoonotic disease control program at the School of Veterinary Medicine, Louisiana State University, was developed by a Health and Safety Committee comprised of members from all instructional departments. The program incorporated safety educational input during the basic, preclinical, and clinical years; a standardized accident reporting procedure; rabies vaccination, with serologic evaluation; a blood serum bank; and recommendations for future control procedures.