Effect of Indigofera aspalathoides on the Expression of Inducible Nitric Oxide Synthase During 7,12-Dimethylbenz[a]anthracene-Induced Hamster Buccal Pouch Carcinogenesis.

Background: The mechanisms of inflammation and carcinogenesis are significantly influenced by nitric oxide (NO). Three different kinds of nitric oxide synthase (NOS) have been previously found: neuronal NOS, inducible nitric oxide synthase (iNOS), and endothelial NOS.

Objectives: This study looked into the properties of iNOS in hamster buccal pouch carcinogenesis caused by 7,12-dimethylbenz[a]anthracene (DMBA).