Management of congenital hypogonadotropic hypogonadism in females.

This review explores the challenges in the diagnosis of hypogonadotropic hypogonadism, the transition of care from paediatric to adult care and the considerable health implications of this condition. The role gynaecologists and general practitioners have in managing hormone replacement therapy and reproductive potential is also highlighted. The fertility treatment options, which include ovulation induction with gonadotrophins and in-vitro fertilisation, are discussed in detail along with highlighting the fact that anovulation and markers of low ovarian reserve prior to priming treatment may not be reflective of poor reproductive potential.

Water stable graphene oxide metal-organic frameworks composite (ZIF-67@GO) for efficient removal of malachite green from water.

Malachite green (MG) is extensively applied in aquaculture worldwide as a therapeutic agent. MG and its primary metabolite leucomalachite green (LMG) are commonly detected in aquaculture products. MG can cause serious health concerns (in vivo carcinogenic/genotoxic).

Effect of metal atom in zeolitic imidazolate frameworks (ZIF-8 & 67) for removal of Pb & Hg from water.

Heavy metals especially lead (Pb) and mercury (Hg) are recognized as most emerging pollutants in underground water and are major threat to public health around the world. Major challenge to mitigate water pollution is construction of effective materials containing a host of deceivingly accessible high-density and high-level efficiency. Herein, we have synthesized two metal-organic frameworks (MOFs) with efficient porosity showing the right combination of structures.