Rational synthesis, biological screening of azo derivatives of chloro-phenylcarbonyl diazenyl hydroxy dipyrimidines/thioxotetrahydropyrimidines and their metal complexes.

Herein, a new series of azo ligands HL-1 , HL-2 HL-3 HL-4 and their metal complexes with Cu(II) & Ni(II) were synthesized successfully having excellent yield, in reproducible conditions and for structure elucidation different advance spectroscopic techniques (FTIR, H NMR, C NMR and Mass Spectrometry) were applied. In FTIR analysis, the absence of peak at due to -NH and presence of a new peak of N=N at 1390-1520 cm confirmed synthesis of the ligands. The H NMR spectra of azo ligands showed singlet peak at 11.