Evaluation of Different Surface Roughening Techniques on Clear Aligner Attachments Bonded to Monolithic Zirconia: Study.

Aim: The objective of this study is to assess the impact of three different surface etching techniques and two composite materials on surface roughness () and the shear bond strength (SBS) of clear aligner attachments bonded to monolithic zirconia (MZ).

Materials And Methods: Sixty-six MZ disks were divided into three main groups ( = 22) according to the surface treatment method: group I: hydrofluoric acid (HFA) 9.5%, group II: 50 µm aluminum oxide (AlO) sandblasting, and group III: Er:Cr:YSGG laser.

Exploring the tumor-suppressive role of miRNA-200c in head and neck squamous cell carcinoma: Potential and mechanisms of exosome-mediated delivery for therapeutic applications.

Head and neck squamous cell carcinoma (HNSCC) remains a challenging malignancy due to its high rates of recurrence, metastasis, and resistance to conventional therapies. microRNA-200c (miRNA-200c) has emerged as a critical tumor suppressor in HNSCC, with the potential to inhibit epithelial-mesenchymal transition (EMT), which is considered as a key process in cancer metastasis and progression. Interestingly, there are also controversial findings in HNSCC characterizing miRNA-200c as oncogenic factor.

Evaluation of pain intensity and airway changes in non-growing patients treated by MARPE with and without micro-osteoperforation: a randomized clinical trial.

Trial Design: Parallel.

Objectives: To assess the effect of mini-screw assisted rapid palatal expansion (MARPE) with/without micro-osteoperforation (MOP) on the airway and pain intensity in non-growing patients with maxillary transverse deficiency.

Method: Two equal groups of twenty-four individuals aged ≥ 19 years old with maxillary transverse deficit were randomly assigned.

Does staining orthodontic adhesive provide an advantage in adhesive resin removal and enamel roughness? An in vitro study.

Background: The removal of adhesive remnants after bracket debonding has been shown to cause damaging effects on the enamel surface. This study aimed to investigate the efficacy of stained adhesive remnant removal (ARR) on enamel roughness compared to translucent composite.

Material And Methods: Thirty extracted premolar teeth were divided equally into three groups; conventional composite control group (CC), stained composite group (SC) and stained bonding solution group (SB).

Interlayer Affected Diamond Electrochemistry.

Diamond electrochemistry is primarily influenced by quantities of sp-carbon, surface terminations, and crystalline structure. In this work, a new dimension is introduced by investigating the effect of using substrate-interlayers for diamond growth. Boron and nitrogen co-doped nanocrystalline diamond (BNDD) films are grown on Si substrate without and with Ti and Ta as interlayers, named BNDD/Si, BNDD/Ti/Si, and BNDD/Ta/Ti/Si, respectively.

Clinical and microbiological efficacy of intra-pocket application of diode laser in grade C periodontitis: a randomized controlled clinical trial.

Background: Periodontitis is a microbially induced disease destroying structures anchoring teeth to jaw bones. Although metronidazole in combination with spiramycin is the effective conventional treatment of stage III grade C periodontitis, it has several systemic side effects. Laser therapy is widely used nowadays as an adjunct to scaling and root planing (SRP) to modulate inflammatory host response and eradicate microbes, due to bactericidal and detoxifying effects.

Effect of silymarin on the relative gene expressions of some inflammatory cytokines in the liver of CCl-intoxicated male rats.

The intensive exposure of the liver cells to any type of noxae, such as viruses, drugs, alcohols, and xenobiotics could induce hepatic inflammation through the upregulation of gene expression of several fibrotic and inflammatory mediators. So, our study assessed the role of silymarin on the inflammatory response induced by carbon tetrachloride (CCl) as an example of xenobiotics on liver tissues in male rats. Forty-eight Wister male rats (weight: 130 ± 10) were housed for 14 days and then divided randomly into six groups: control, SLY: rats received only silymarin orally for 12 weeks (daily), CO: rats were injected with corn oil for 8 weeks (3 times weekly), CCl: rats were injected with CCl solubilized in corn oil for 8 weeks (day by day), Treated: rats received silymarin for 4 weeks after CCl injection, Protected: rats received silymarin for 4 weeks before and 8 weeks during CCl injection.

First monitoring of resistance and corresponding mechanisms in the green peach aphid, Myzus persicae (Sulzer), to registered and unregistered insecticides in Saudi Arabia.

Insecticides are widely used as the primary management strategy for controlling Myzus persicae, the devastating pest ravaging various vegetables, fruits, crops, and ornamentals. This study examined the susceptibility of M. persicae field populations to bifenthrin, fosthiazate, acetamiprid, spirotetramat, afidopyropen, and flonicamid while exploring the possible metabolic mechanisms of resistance.

Biological Fitness Cost, Demographic Growth Characteristics, and Resistance Mechanism in Alpha-Cypermethrin-Resistant (Diptera: Muscidae).

L., a pest of animals and humans, has developed resistance to alpha-cypermethrin, a pyrethroid insecticide commonly used to control medically important pests in many countries, including Saudi Arabia. We investigated the mechanism underlying the development of alpha-cypermethrin resistance and life history characteristics of alpha-cypermethrin-susceptible (Alpha-SS) and alpha-cypermethrin-resistant (Alpha-RS) using the age-stage, two-sex life table theory, which is crucial for developing a future rational management strategy and minimizing the negative effects of alpha-cypermethrin on the environment.

Evaluation of enamel roughness after orthodontic debonding and clean-up procedures using zirconia, tungsten carbide, and white stone burs: an in vitro study.

Background: The main goal of orthodontic debonding is to restore the enamel surface as closely as possible to its pretreatment condition without iatrogenic damage. This study aimed to compare the effects of different adhesive removal burs; zirconia burs, tungsten carbide burs, and white stone burs on enamel surface roughness.

Materials And Methods: Total sample of 72 extracted premolars was randomly divided into three equal groups (n = 24) depending on the method of adhesive removal: zirconia burs (ZB); tungsten carbide burs (TC); and white stones (WS).

Investigation of Antifungal Action of Fractions CHNO Isolated from extract Isolated from Zee maize.

Background: Plants are harmed by parasitic organisms, and toxic poisons are created. Phytopathogenic fungi create toxins that can severely harm plants' basic physiological functioning.

Objective: Investigation of antifungal impact of various fractions of methanol extract of to as a plant pathogen.

Dentofacial effects of miniscrew-anchored maxillary protraction on prepubertal children with maxillary deficiency: a randomized controlled trial.

Background: The introduction of bone-anchored maxillary protraction eliminated the side effects of facemask in the early treatment of patients with maxillary retrusion. This study aimed to evaluate the effects of miniscrew-anchored maxillary protraction (MAMP) and compare them with the growth changes in an untreated control group in growing patients with Class III malocclusion.

Methods: Forty growing patients with Class III malocclusion and retrognathic maxilla were randomly allocated into two groups: treated and control groups.

The medicinal activity of lyophilized aqueous seed extract of Lepidium sativum L. in an androgenic alopecia model.

This study evaluated the topical effect of Lepidium sativum lyophilized seed extract (LSLE) towards Sustanon-induced alopecia in male adult Wistar albino rats in vivo, compared to minoxidil topical reference standard drug (MRD). LC-MS/MS together with molecular networking was used to profile the metabolites of LSLE. LSLE treated group revealed significant changes in alopecia related biomarkers, perturbation of androgenic markers; decline in testosterone level and elevation in 5α-reductase (5-AR); decline in the cholesterol level.

Comparison of Enamel Surface Roughness after Bracket Debonding and Adhesive Resin Removal Using Different Burs with and without the Aid of a Magnifying Loupe.

Aim: This study aimed to evaluate the impact of using a magnifying dental loupe on enamel surface roughness during adhesive resin removal by different burs.

Materials And Methods: Ninety-six extracted premolar teeth were randomly divided according to the bur used with or without the aid of a magnifying loupe into four equal groups ( = 24): group I: naked eye tungsten carbide burs (NTC); group II: magnifying loupe tungsten carbide burs (MTC); group III: naked eye white stones (NWS); and group IV: magnifying loupe white stones (MWS). The initial surface roughness () T0 was evaluated using a profilometer, and the scanning electronic microscopy (SEM) technique.

Alpha-Cypermethrin Resistance in : Resistance Instability, Realized Heritability, Risk Assessment, and Insecticide Cross-Resistance.

L., the common house fly, is a cosmopolitan carrier of human and livestock disease pathogens. The species exhibits resistance to many insecticides; therefore, effective insecticide resistance management programs are required worldwide.

Rate of upper incisor retraction in Class II division 1 patients managed with palatal versus buccal miniscrew supported segmental orthodontics: Randomized parallel clinical trial.

Objective: This study was conducted to compare maxillary incisor retraction rates using buccal orthodontics with segmented arch approach supported by a buccal or palatal mini-screw in non-growing Class II Division 1 patients during a 3-month period.

Patients And Methods: All patients between September 2018 and December 2021 with following criteria were included: non-growing class II division 1 protrusion, indication for premolar extraction, no or little crowding, normal overbite, no previous orthodontic treatment, no systematic disease, good oral hygiene, no periodontal problems or oral habits. Mini-implant was inserted buccally or palatally between upper second premolar and first molar bilaterally.

Prophylactic and curative effects of Carica papaya Linn. pulp extract against carbon tetrachloride-induced hepatotoxicity in male rats.

Several chemicals and medications induce cellular damage in various organs of the body by activating reactive substances' metabolism leading to various pathological conditions including liver disease. In this study, we evaluated the prophylactic and curative effects of Carica papaya Linn. pulp water extract (PE) against CCl-induced rat hepatotoxicity.

Realized Heritability, Risk Assessment, and Inheritance Pattern in (Lepidoptera: Noctuidae) Resistant to Dipel ( Kurstaki).

Fabricius is a potential cotton and okra pest in South Asia. The realized heritability, risk assessment, and inheritance mode of Kurstaki (Btk) resistance were determined in the Dipel-selected (DIPEL-SEL) . The DIPEL-SEL strain had a 127.

Development of Semisynthetic Apoptosis-Inducing Agents Based on Natural Phenolic Acids Scaffold: Design, Synthesis and In-Vitro Biological Evaluation.

A crucial target in drug research is magnifying efficacy and decreasing toxicity. Therefore, using natural active constituents as precursors will enhance both safety and biological activities. Despite having many pharmacological activities, caffeic and ferulic acids showed limited clinical usage due to their poor bioavailability and fast elimination.

Toxicities and Cross-Resistance of Imidacloprid, Acetamiprid, Emamectin Benzoate, Spirotetramat, and Indoxacarb in Field Populations of (Diptera: Culicidae).

is a major vector of several pathogens and is capable of breeding in various aquatic habitats. The extensive and injudicious use of synthetic chemicals against the mosquito species has led to the problem of insecticide resistance. To explore this resistance in detail, toxicity bioassays of imidacloprid, acetamiprid, emamectin benzoate, spirotetramat, and indoxacarb were performed on five field populations from Pakistan in addition to a laboratory susceptible strain.

A Deep Learning Model for Stroke Patients' Motor Function Prediction.

Deep learning models are effectively employed to transfer learning to adopt learning from other areas. This research utilizes several neural structures to interpret the electroencephalogram images (EEG) of brain-injured cases to plan operative imagery-computerized interface models for controlling left and right hand movements. This research proposed a model parameter tuning with less training time using transfer learning techniques.

A Decoding Prediction Model of Flexion and Extension of Left and Right Feet from Electroencephalogram.

Detection of limb motor functions utilizing brain signals is a significant technique in the brain signal gain model (BSM) that can be effectively employed in various biomedical applications. Our research presents a novel technique for prediction of feet motor functions by applying a deep learning model with cascading transfer learning technique to use the electroencephalogram (EEG) in the training stage. Our research deduces the electroencephalogram data (EEG) of stroke incidence to propose functioning high-tech interfaces for predicting left and right foot motor functions.

Investigation of the potential anti-urolithiatic activity of Alhagi maurorum (Boiss.) grown wild in Al-Ahsa (Eastern Province), Saudi Arabia.

The potential of Alhagi maurorum (Boiss.) aqueous extract (AME), used in traditional medicine for treatment or prevention of urolithiasis, to dissolve calcium oxalate stones in vitro was evaluated. In order to determine the litholytic potential of the extract, Calcium oxalate urinary stones were incubated during 12 weeks under continuous shaking in the presence of AME, Rowanix or NaCl 9 g/mL solution were used as controls.

Risk assessment of resistance to diflubenzuron in Musca domestica: Realized heritability and cross-resistance to fourteen insecticides from different classes.

The Musca domestica L. is a well-known vector for a number of livestock and human diseases. One major challenge for maintaining effective control of this pest is its propensity to develop resistance to insecticides.