Integrated process analysis retrieval of changes in ground-level ozone and fine particulate matter during the COVID-19 outbreak in the coastal city of Kannur, India.

The Community Multi-Scale Air Quality (CMAQ) model was applied to evaluate the air quality in the coastal city of Kannur, India, during the 2020 COVID-19 lockdown. From the Pre1 (March 1-24, 2020) period to the Lock (March 25-April 19, 2020) and Tri (April 20-May 9, 2020) periods, the Kerala state government gradually imposed a strict lockdown policy. Both the simulations and observations showed a decline in the PM concentrations and an enhancement in the O concentrations during the Lock and Tri periods compared with that in the Pre1 period.

Facile electrooxidation of ethanol on reduced graphene oxide supported Pt-Pd bimetallic nanocomposite surfaces in acidic media.

Development of electrocatalysts with extended homogeneity and improved metal-support interactions is of urgent scientific need in the context of electrochemical energy applications. Herein, bimetallic Pt-Pd nanoparticles with good homogeneity are fabricated using a convenient solution phase chemical reduction method onto a reduced graphene oxide (rGO) support. X-ray diffraction studies revealed that Pt-Pd/rGO possesses the crystallite size of 3.

Clinical Evaluation of Pediatric Posterior Zirconia and Stainless Steel Crowns: A Comparative Study.

Objective: To clinically evaluate and compare the performance of posterior pediatric zirconia crowns with stainless steel crowns.

Materials And Methods: Twenty nine children [3-9 years] were selected and given 70 preformed crowns [35: preformed zirconia crowns, Kinderkrown; 35: stainless steel crowns, KIDZ CROWN]. Crowns were evaluated for retention, marginal integrity, opposing tooth wear, plaque accumulation, gingival inflammation, and proximal contact at 3, 6, 9, and 12th month.

Effect of OH substitution in 3-benzylchroman-4-ones: crystallographic, CSD, DFT, FTIR, Hirshfeld surface, and energy framework analysis.

3-Benzylchroman-4-ones (homoisoflavanones) are oxygen-containing heterocycles with a sixteen-carbon skeleton. They belong to the class of naturally occurring polyphenolic flavonoids with limited occurrence in nature and possess anti-inflammatory, antibacterial, antihistaminic, antimutagenic, antiviral, and angioprotective properties. Recently, we reported the synthesis and anticancer activity studies of fifteen 3-benzylchroman-4-one molecules, and most of them were proven to be effective against BT549 and HeLa cells.

Knowledge, Attitude and Health Practice towards Cardiovascular disease in Health care providers: A Systematic Review.

The prevalence of cardiovascular disorders among healthcare providers have been increasing in the past few years and research conducted in this aspect have identified various risk factors that affect cardiovascular health: like shift work, high stress, anxiety, work environment, obesity, high basal metabolic index, and others. PRISMA guidelines were followed and data search was conducted on PubMed, PMC, MEDLINE, and Google Scholar wherein the identification and screening led to 31 selected studies on identification of knowledge, perception and attitude of the healthcare providers regarding their cardiovascular disorders. Results reveal that knowledge level even although high in healthcare providers regarding their cardiovascular health, the attitude or perception differs among them.

Knowledge, perceived threats and protective behaviour related to COVID 19 among pregnant women.

Unlabelled: Pregnancy is usually a period of joy, happiness, and expectation for a baby. However, COVID-19 changed the priority and created an environment of worry, perceived threats, and increased protective behaviour to safeguard mother and baby against COVID-19.

Method: A cross-sectional study was conducted to assess, the level of knowledge, perceived threats, protective behavior, and factors affecting protective behavior among pregnant women by using a convenient sampling technique.

Clinical Profile of Lung Cancer in Females- A Single Institution Study.

The global incidence of lung cancer among women is rising. By 2030, lung cancer in women is expected to increase by 43%. The factors thought to predispose women to lung cancer are exposure second hand smoke, air pollution and biofuels used for cooking.

Assessing the Prognostic Value of Crp/Albumin Ratio and Lactate/Albumin Ratio in Critically Ill Patients.

Unlabelled: The ability to predict the fate of critically ill patients admitted to an intensive care unit is very important, as there are only few studies which have focused on this aspect. Our study has focused to determine the relationship between C-Reactive protein/Albumin ratio (CAR) and Lactate/Albumin ratio (LAR) and Intensive care unit stay, the requirement for vasopressor and mechanical ventilator support, recovery and mortality in the patients admitted to critical care unit.

Material: The study group comprised of 100 patients who were admitted to critical care unit.

Study of Serum Uric Acid Levels in Patients of Metabolic Syndrome in a Tertiary Care Centre in South India.

Unlabelled: The prevalence of Hyperuricemia is increasing even in developing countries. Hyperuricemia may be asymptomatic in many cases. It has been known to be associated with metabolic syndrome.

Food insecurity and associated depression among older adults in India: evidence from a population-based study.

Objective: The present study aimed to examine the associations of several indicators of food insecurity with depression among older adults in India.

Design: A cross-sectional study was conducted using country-representative survey data.

Setting And Participants: The present study uses data of the Longitudinal Aging Study in India conducted during 2017-2018.

Nivolumab Immunotherapy-Related Skin Reactions Detected on 18F-FDG PET/CT in Renal Cell Cancer.

Nivolumab, a fully human immunoglobulin G4 anti-programmed cell death 1 antibody, provides a novel therapy option for patients with metastatic cancers. Immunotherapy agents have been associated with immune-related adverse events (irAEs), which may be detected on 18F-FDG PET/CT. Cutaneous toxicities are one of the most common irAEs in the form of maculopapular rash (eczema-like spongiotic dermatitis) and pruritus.

Clinical Outcome of Idiopathic Membranous Nephropathy-A Single Centre Study.

Introduction: Idiopathic Membranous nephropathy (IMN) is one of the most common causes of adult onset nephrotic syndrome worldwide. About 50% will slowly progress to renal failure if untreated.

Methods: We did a retrospective study in patients with Idiopathic membranous nephropathy who were on follow-up between 2016-2018 at Madras medical college, Chennai.

To Study Adverse Effect following Immunization (AEFI) and COVID-19 Infection amongst COVID-19 Vaccine Benefeciaries.

Unlabelled: COVID-19 vaccines have been rolled out recently in several parts of the world. Little is known about the post-vaccination experience outside of clinical trial conditions. The aim of this study was to investigate the adverse effects and infection rate of vaccinated people in a community scenario.

Compliance and Patients' Perspectives Towards Nutritional Supplementation Following Bariatric Surgery.

Background: Nutritional supplementation is recommended as a prophylactic strategy for nutritional deficiencies after bariatric surgery. Little is known regarding compliance and patients' perspectives. The purpose of the study was to explore supplement intake, compliance, and patients' perspectives (including barriers, facilitators, and beliefs) and to examine whether compliance to nutritional supplementation can be predicted after bariatric surgery.

Ochronotic Surprise during Total Knee Replacement! A Case Report.

Introduction: Alkaptonuria is a rare autosomal recessive metabolic disorder characterized by accumulation of homogentisic acid (HGA) due to an inherited deficiency of the enzyme HGA oxidase. Unlike rheumatoid arthritis which affects the small joints of the hands and feet, ochronotic arthropathy predominantly involves the large weight-bearing joints such as hips, knees, and spine. The knee is the most common joint to be affected.

Structural patterns in class 1 major histocompatibility complex-restricted nonamer peptide binding to T-cell receptors.

The startling diversity in αβ T-cell receptor (TCR) sequences and structures complicates molecular-level analyses of the specificity and sensitivity determining T-cell immunogenicity. A number of three-dimensional (3D) structures are now available of ternary complexes between TCRs and peptides: major histocompatibility complexes (pMHC). Here, to glean molecular-level insights we analyze structures of TCRs bound to human class I nonamer peptide-MHC complexes.

First glanders cases detected in Nepal underscore the need for surveillance and border controls.

Background: Glanders is a transmissible zoonotic disease caused by Burkholderia mallei that infects equids and humans. No glanders cases in equids were reported so far in Nepal.

Case Presentation: Following suspected glanders in animals with clinical signs in different regions in Nepal, serum samples were tested by CFT, ELISA and Luminex® tests.

A Comparative Study on Safety and Efficacy of Desvenlafaxine Versus Sertraline in Depression.

Background Depression is one of the most predominant mental health issues that are prevalent now. Therefore, many clinical trials were being conducted to find the safest, most effective, and tolerable anti-depressant. This study aims to compare desvenlafaxine and sertraline regarding their safety and efficacy in treating depression.

A plant-based diet differentially affects the global hepatic methylome in rainbow trout depending on genetic background.

Replacing fish meal and oil in trout diets with plant-derived ingredients is a contemporary challenge to move towards more sustainable aquaculture practices. However, such dietary replacement causes hepatic metabolic changes that have not yet been elucidated. Here, we aimed to decipher the effect of a 100% plant-based diet on the hepatic global DNA methylation landscape in trout and assess whether changes depend on fish genetic background.

Determination of impervious area of Saroor Nagar Watershed of Telangana using spectral indices, MLC, and machine learning (SVM) techniques.

Urbanization affects the local wind and water cycle by changing the natural surface and atmospheric conditions, which further changes the local climate and climate system. Assessment of built-up-area changes in a rapidly growing urban area within a short time is a prime factor for administrators for better environmental assessment and sustainable development of urban areas. Traditional survey approaches, on the other hand, are unable to meet the demand for rapid urban land management development, and there is a pressing need to develop new methods to address the limitations of existing ones.

Are Intertrochanteric Fractures Evolving? Trends in the Elderly Population over a 10-Year Period.

Background: Intramedullary devices for the fixation of intertrochanteric fractures are increasing in usage and popularity. This reflects either a shift in adoption of new technology or intertrochanteric fractures becoming more complex or unstable. This trend was observed in our institution, hence we set out to investigate if this was concordant with an associated change in the demographics of the patients or in the morphology of the intertrochanteric fracture pattern over a 10-year period.

Impact of uterine epithelial cells and its conditioned medium on the in vitro embryo production in buffalo (Bubalusbubalis).

One of the challenges usually needs to be addressed in animal embryo production is to create the appropriate in vitro culture to improve blastocyst rate and produce high quality embryos. The present work was undertaken to investigate the impact of uterine epithelial cells and its conditioned medium (CM) on in vitro embryo production in buffalo. Buffalo uterine epithelial cells (UECs) were successfully isolated, cultured and characterized from slaughterhouse derived non gravid uteri.

Draft genome sequences data of rare sub sp. serovar Ceyco and serovar Hillegersberg isolated from diarrheal patients in India.

We report here the draft genome sequence of two rare serotypes, isolated from human faecal samples in India. The isolates were identified as subsp serovar Ceyco and serovar Hillegersberg by Wole genome sequencing (WGS) based serotype prediction. The genomic similarity of study isolates was identified by clustering with the global collection of sp.