Publications by authors named "Hae-In Lim"
BMC Complement Med Ther
February 2024
Article Synopsis
- - The herbal prescription SH003, designed to treat non-small cell lung cancer (NSCLC), was analyzed through network pharmacology to examine its active compounds, targets, and biological pathways involved in treating the disease.
- - Researchers identified 20 active compounds in SH003 and found 239 shared targets between SH003 and NSCLC, highlighting 79 key hub genes such as TP53 and AKT1 essential for NSCLC treatment.
- - Experimental validations confirmed SH003's effectiveness against NSCLC by showing reduced cell viability and downregulated hub genes, while LC-MS analysis identified four key active compounds within SH003 that could play a significant role in its therapeutic effects.
