Neuroprotective Effect of Wurmb by Suppressing TRPV1 Following Sciatic Nerve Crush Injury in a Rat.

Peripheral nerve injury can result in severe functional impairment and decreased quality of life due to loss of sensory and motor function. wurmb (NF) has been used in diverse folk remedies in East Asia. We have previously shown that wurmb extract has antinociceptive and anti-inflammatory effects by suppressing TRPV1 in the sciatic nerve injury.