CAD/CAM for scalable nanomanufacturing: A network-based system for hybrid 3D printing.

Micro- and nano-structuring have been highlighted over several decades in both science and engineering fields. In addition to continuous efforts in fabrication techniques, investigations in scalable nanomanufacturing have been pursued to achieve reduced feature size, fewer constraints in terms of materials and dimensional complexity, as well as improved process throughput. In this study, based on recent micro-/nanoscale fabrication processes, characteristics and key requirements for computer-aided design and manufacturing (CAD/CAM) systems for scalable nanomanufacturing were investigated.

Characterization of the aminopyridine derivative KRC-180 as a JAK2 inhibitor.

Janus kinase 2 (JAK2) is a non-receptor tyrosine kinase that regulates the signal transducer and activator of transcription (STAT) signaling pathway. Deregulation of JAK2 signaling has previously been observed in hematologic malignancies, including erythroleukemia. In the present study, an aminopyridine derivative compound, KRC-180, exhibited direct inhibition of the JAK2 protein at the catalytic site, as demonstrated using kinase activity assays and docking analyses.

Gender Differences in the Routine Activities Associated With Risks for Larceny in South Korea.

The present research uses data from the 2010 Korean National Criminal Victimization Survey to examine gender differences in larceny victimization and in predictors of victimization (i.e., target attractiveness, exposure to potential offenders, target hardening, guardianship, and proximity to crime and social disorder) identified by routine activity theory.

Aerodynamically focused nanoparticle (AFN) printing: novel direct printing technique of solvent-free and inorganic nanoparticles.

Aerodynamically focused nanoparticle (AFN) printing was demonstrated for direct patterning of the solvent-free and inorganic nanoparticles. The fast excitation-purge control technique was proposed and investigated by examining the aerodynamic focusing of nanoparticles and their time-scale, with the analytical and experimental approaches. A series of direct patterning examples were demonstrated with Barium Titanate (BaTiO3) and Silver (Ag) nanoparticles onto the flexible and inflexible substrates using the AFN printing system.

Graphene-ionic liquid based hybrid nanomaterials as novel lubricant for low friction and wear.

Hybrid nanomaterials offer potential scope for an increasing number of novel applications when engineered to deliver usefully functional properties. Recent advancements in the design of new material products that result from interactions among different compositions at the nanoscale and microscale has led to innovative ways to fabricate and process hybrids with altered structural physicochemical properties. An example is the development of novel "lubricants" that make use of ionic liquids (ILs) and their ability to induce exploitable molecular assemblies at the IL-graphene interface.

A rotational ablation tool for calcified atherosclerotic plaque removal.

Atherosclerosis is a major cardiovascular disease involving accumulations of lipids, white blood cells, and other materials on the inside of artery walls. Since the calcification found in the advanced stage of atherosclerosis dramatically enhances the mechanical properties of the plaque, restoring the original lumen of the artery remains a challenge. High-speed rotational atherectomy, when performed with an ablating grinder to remove the plaque, produces much better results in the treatment of calcified plaque compared to other methods.