Assessment of adherence to treatment with injectable extended-release antipsychotics within a pharmacotherapeutic follow-up program.

Objective: To describe an injectable extended-release antipsychotic pharmacotherapeutic follow-up program and to assess  adherence among patients included in the program.

Method: A coordinated program is described involving hospital and  primary care pharmacy, which included electronic prescription,  reviewing, and dispensing of injectable antipsychotic agents in mental  health and primary health care centers. Adherence to treatment was  assessed in a 1-month prospective observational cross-sectional study  which included all patients under treatment with injectable extended- release antipsychotics in a health area of more than 500,000  inhabitants.

Devising of a risk map on the management of high risk alert medication in a high level university hospital.

Objective: To classify hospital units into three risk levels in order to define and prioritise  improvement and training measures in each of them.

Method: The risk map was developed in two phases: First phase involved the setting up of a  multidisciplinary team, a bibliographic search, the identification of medications and of the criteria to  design the map: (1) Location: number of high-alert medications; (2) Staff turnover: the units were  classified in low turnover units = 1, medium turnover units = 2 and high turnover units = 3 according  to data provided by the human resource department; (3) Frequency: quotient between the number of high alert medicactions in each unit and the total of medications used, and (4) Severity: voluntary  survey of professionals. An accumulated risk of severity of each unit was calculated: Σ (severity of the  drug x number of its units).

Assessment of different mouthwashes on cannabis oral fluid concentrations.

Since the implementation of mandatory drug testing in drivers' oral fluid, several solutions to avoid an onsite positive result can be found on drug users' forums, especially for marijuana, including the use of different mouthwashes. Recently, a product for personal hygiene, Kleaner, has been sold for this purpose. The aims of this study were to assess the effect of water, whole milk, and Kleaner mouthwashes on tetrahydrocannabinol (THC) oral fluid concentrations, and those observed in passive smokers subjected to extreme contamination conditions.