Publications by authors named "Hadi S"

This paper proposes a new extension of the well-known -special function, which is called -function. We introduce this function by drawing inspiration from exponential function. This new special function is studied from a variety of analytical perspectives, including differential and integral operators.

View Article and Find Full Text PDF

Estimating individual age from DNA methylation at age associated CpG sites may provide key information facilitating forensic investigations. Systematic marker screening and feature selection play a critical role in ensuring the performance of the final prediction model. In the discovery stage, we screened for 811876 CpGs from whole blood of 2664 Chinese individuals ranging from 18 to 83 years of age based on a stepwise conditional epigenome-wide association study (SCEWAS).

View Article and Find Full Text PDF

Objective: To identify the COVID-19 pandemic impact on well-being/mental health, coping strategies, and risk factors in adolescents worldwide.

Method: This study was based on an anonymous online multi-national/multi-language survey in the general population (representative/weighted non-representative samples, 14-17 years of age), measuring change in well-being (World Health Organization-Five Well-Being Index [WHO-5]/range = 0-100) and psychopathology (validated composite P-score/range = 0-100), WHO-5 <50 and <29, pre- vs during COVID-19 pandemic (April 26, 2020-June 26, 2022). Coping strategies and 9 a priori- defined individual/cumulative risk factors were measured.

View Article and Find Full Text PDF

Background And Aims: Alternative therapies, such as zinc supplementation, have been explored as potential interventions for sleep disorders. However, the efficacy of zinc supplementation in improving sleep quality remains uncertain. This systematic review aims to examine the impacts of zinc supplementation on sleep quality in humans.

View Article and Find Full Text PDF
Article Synopsis
  • The COH-FIT study is a large, multi-country survey aimed at identifying factors affecting wellbeing and mental health outcomes during the COVID-19 pandemic, involving a representative sample of 121,066 adults.
  • Researchers analyzed both modifiable (like coping strategies and pre-pandemic stress) and non-modifiable factors (such as age, gender, and socioeconomic status), finding significant negative effects on wellbeing and psychopathology scores during the pandemic.
  • The study identified 15 modifiable and 9 non-modifiable risk factors, alongside 13 modifiable and 3 non-modifiable protective factors, emphasizing the importance of social support and coping strategies in mental health outcomes.
View Article and Find Full Text PDF
Article Synopsis
  • There is a lack of comprehensive international studies examining multidimensional mental health and wellbeing before and during the COVID-19 pandemic, particularly identifying at-risk groups and effective coping strategies.
  • The COH-FIT survey, conducted from April 2020 to June 2022 in 30 languages, assessed changes in well-being and psychopathology among over 121,000 participants, revealing significant declines in mental health during the pandemic.
  • Key findings indicated that certain demographics, such as young adults and people in low-income countries, were particularly affected, while coping strategies like exercise, internet use, and maintaining social contacts emerged as the most effective for managing stress.
View Article and Find Full Text PDF
Article Synopsis
  • * Out of 85 analyzed videos, the average content score was low, with significant gaps in crucial information such as disease progression and the importance of screening for related health issues.
  • * The overall quality of the videos was rated as partially sufficient, with better ratings for videos from recognized sources, particularly in terms of transparency regarding sponsorship.
View Article and Find Full Text PDF
Article Synopsis
  • * This study focuses on creating and testing new compounds (pyrazoline-phenoxyacetic acid derivatives) with 6a and 6c showing strong COX-2 inhibition and selectivity, which could be effective in treating inflammation without harmful side effects.
  • * Safety assessments of these compounds demonstrated positive results in male Wistar rats, with no adverse effects on vital organs, and molecular docking studies confirmed their therapeutic potential through significant interactions with COX-2.
View Article and Find Full Text PDF

Anisotropic cellulose nanofiber (CNF) foams represent the state-of-the-art in renewable insulation. These foams consist of large (diameter >10 μm) uniaxially aligned macropores with mesoporous pore-walls and aligned CNF. The foams show anisotropic thermal conduction, where heat transports more efficiently in the axial direction (along the aligned CNF and macropores) than in the radial direction (perpendicular to the aligned CNF and macropores).

View Article and Find Full Text PDF

One approach to addressing bone defects involves the field of bone tissue engineering, with scaffolds playing an important role. The properties of the scaffold must be similar to those of natural bone, including pore size, porosity, interconnectivity, mechanical attributes, degradation rate, non-toxicity, non-immunogenicity, and biocompatibility. The primary goals of this study are as follows: first, to evaluate hydroxyapatite (HA)/polycaprolactone (PCL)/gelatin nanofiber scaffolds based on functional groups, fibre diameter, porosity, and degradation rate; second, to investigate the interaction between HA/PCL/gelatin scaffolds and osteoblast cells (specifically, the ATCC 7F2 cell line) using assays, including cell viability and adhesion levels.

View Article and Find Full Text PDF

The study of holomorphic functions has been recently extended through the application of diverse techniques, among which quantum calculus stands out due to its wide-ranging applications across various scientific disciplines. In this context, we introduce a novel q-differential operator defined via the generalized binomial series, which leads to the derivation of new classes of quantum-convex (q-convex) functions. Several specific instances within these classes were explored in detail.

View Article and Find Full Text PDF
Article Synopsis
  • Facial morphology is a complex genetic trait that is important for evolutionary studies, but fossil evidence for ancient humans like Neanderthals and Denisovans is limited.
  • A large-scale study of 9674 East Asians and 10,115 Europeans identified 71 genetic loci linked to facial features and developed a predictive tool called the facial polygenic score (FPS).
  • By applying the FPS to ancient DNA, researchers found that Neanderthals and Denisovans likely had similar facial features, contributing to our understanding of human evolutionary history.
View Article and Find Full Text PDF

Bovine tuberculosis (bTB), caused by (), is a globally prevalent zoonotic infectious disease. World Organization for Animal Health (WOAH) estimates indicate that up to 10% of the total human TB cases in developing countries are attributed to . Pakistan ranks 4th in global milk production with a livestock population of over 212 million animals.

View Article and Find Full Text PDF

Background: Overweight and obesity are the most critical risk factors for chronic diseases. The quality of dietary fatty acids as one of the factors affecting fat accumulation has received little attention. This study investigates the association between dietary linoleic acid (LA) and alpha-linolenic acid (ALA) with body fat indices in a sample of healthy Iranian adults.

View Article and Find Full Text PDF

The upcycling of discarded garments can help to mitigate the environmental impact of the textile industry. Here, we fabricated hybrid anisotropic foams having cellulose nanocrystals (CNCs), which were isolated from discarded cotton textiles and had varied surface chemistries as structural components, in combination with xanthan gum (XG) as a physical crosslinker of the dispersion used for foam preparation. All CNCs had crystallinity indices above 85 %, zeta potential values below -40 mV at 1 mM NaCl, and true densities ranging from 1.

View Article and Find Full Text PDF

Agricultural plantations in Indonesia and Malaysia yield substantial waste, necessitating proper disposal to address environmental concerns. Yet, these wastes, rich in starch and lignocellulosic content, offer an opportunity for value-added product development, particularly amino acid production. Traditional methods often rely on costly commercial enzymes to convert biomass into fermentable sugars for amino acid production.

View Article and Find Full Text PDF

Osteoinduction, and/or osteoconduction, and antibacterial characteristics are prerequisites for achieving successful bone grafting. This study aimed to coat bone allografts with silver nanoparticles and assess their antibacterial activity and biocompatibility compared to uncoated bone allografts. In this study, the bone allografts were coated with varying concentrations of silver nanoparticles (5 mg/l, 10 mg/l, and 50 mg/l) through a simple adsorption technique.

View Article and Find Full Text PDF

This study presents a novel packaging film based on whey protein isolate/κ-carrageenan (WC) with red grape pomace anthocyanins (RGA) to investigate its impact on some qualitative attributes of emergency food bars (EFBs) for 6 months at 38°C. Increasing the RGA dose in WC films from 5% (WCA5) to 10% (WCA10) reduced hydrogen bonding between polymers and polymer homogeneity in the matrix according to FTIR and SEM. Tensile strength slightly declined in WCA5 from 7.

View Article and Find Full Text PDF

Objective: To perform a longitudinal study for determining the development of ocular graft-versus-host disease (oGVHD) after allogeneic hematopoietic stem cell transplant (HSCT) and report cases that illustrate the "window of opportunity" concept in oGVHD treatment.

Methods: Patients (n=61) were examined at prescheduled clinic visits before HSCT and three-month intervals after HSCT for 2 years. The presence or absence of oGVHD was determined using the international chronic oGVHD consensus group diagnostic criteria.

View Article and Find Full Text PDF

Background And Aim: Candida albicans and Candida tropicalis, can cause superficial infections of the oral mucosa as well as disseminated bloodstream and deep-tissue infections. The most frequently employed class of antifungals used for Candida infection treatment are the azole antifungals. Their low price, low toxic qualities, and availability for oral use make fluconazole and similar azole antifungals the preferred treatment for various infections caused by Candida.

View Article and Find Full Text PDF
Article Synopsis
  • The pncA gene mutations in Mycobacterium tuberculosis are linked to resistance against the antibiotic pyrazinamide (PZA), with notable differences between sensitive and resistant strains.
  • The study identified three specific mutations in the resistant strain (pncAR1) that altered key amino acids, resulting in decreased enzyme activity for activating PZA.
  • The findings suggest a need for further structural studies on the mutated PZase protein to better understand how these mutations contribute to drug resistance and to aid in the design of more effective tuberculosis treatments.
View Article and Find Full Text PDF

Introduction: A previous meta-analysis reported the positive effects of statin therapy on endothelial function. However, the obtained result had several limitations that necessitated updating the information in this field. Therefore, a systematic and meta-analysis review was conducted to determine whether statin therapy could improve endothelial function, as assessed by flow-- mediated dilation (FMD).

View Article and Find Full Text PDF

The study aimed to determine if deranged liver function tests (LFTs) can predict severe dengue or mortality. It included 135 dengue patients, with a mean age of 30.9 ± 12.

View Article and Find Full Text PDF

 Multiple solutions are currently used to cleanse a deep neck infection (DNI), and a variety of devices are available to deliver wound irrigation solutions. An essential difference between these devices is the pressure that the irrigation solution exerts over the wound tissue.  To compare low-pressure and high-pressure irrigation delivery systems for wound cleansing in DNI.

View Article and Find Full Text PDF

Social media networks such as Facebook, Twitter, WhatsApp, and YouTube are among the most commonly used social networks among people. If used properly, they can contribute to enhancing individual knowledge and scientific values. The study aimed to investigate the use of social media networks for healthy nutritional practices among deaf and hearing students.

View Article and Find Full Text PDF