Publications by authors named "Hadi Rezaeean"
Objective: Breast cancer (BC) is one of the most common diseases in women globally, with an increasing number of deaths associated with it. Recently the role of polymorphisms in the genes encoding cytokines and immune cells has been demonstrated. This study aimed to evaluate the association of IFN-Ɣ + 874 A/T polymorphism with BC clinical symptoms.
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- - Breast cancer (BC) is a common cancer in women, with genetic mutations, particularly in the CHEK2 gene, playing a crucial role in its development and progression.
- - CHEK2 mutations influence cell signaling pathways and can cause BC cells to become resistant to chemotherapy, as well as promote the spread of cancer to other parts of the body.
- - Identifying CHEK2 mutations can serve as a useful prognostic tool to predict patient treatment response and to target specific downstream molecules involved in breast tumor growth, helping distinguish patients at risk for metastasis.
Aberrant expression of CD5 (as a T-cell marker) is seen in some leukemia and lymphoma of B lineage origin. Given that the signaling resulting from the expression of this marker plays an essential role in the development of leukemia and lymphoma, evaluating the expression of this marker is of paramount importance. Therefore, our goal in this study was to investigate the prognostic importance of CD5 expression in B-cell leukemia and lymphoma.
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