Association of GST gene polymorphism and noise-induced hearing loss: GST gene polymorphism and NIHL.

Background: It has been proposed that Noise-induced hearing loss is a complex disease that is combination of environmental and genetic factors. There are inconsistent results concerning the association between variation in glutathione S-transferase () genetic polymorphisms ( rs1049055 and rs10712361) and susceptibility to Noise-induced hearing loss.

Objective: This study was designed to assess the association between gene polymorphism and Noise-induced hearing loss among noise-exposed workers.

Bronchodilator Response of FEV6 and FEV3 as Surrogates of Forced Vital Capacity.

Background: Spirometry as a non-invasive and inexpensive test is widely used for occupational health evaluations. Bronchodilator test is used for the assessment of airflow limitation and increase in forced expiratory volume in 1 second (FEV1) or forced vital capacity (FVC) is considered as a positive response. This study was performed to assess the response of forced expiratory volume in 6 seconds (FEV6), forced expiratory volume in 3 seconds (FEV3), and forced expiratory time (FET) to bronchodilator administration.