Introduction: Functional near-infrared spectroscopy (fNIRS) is an imaging method in which a light source and detector are installed on the head; consequently, the re-emission of light from human skin contains information about cerebral hemodynamic alteration. The spatial probability distribution profile of photons penetrating tissue at a source spot, scattering into the tissue, and being released at an appropriate detector position, represents the spatial sensitivity.
Methods: Modeling light propagation in a human head is essential for quantitative near-infrared spectroscopy and optical imaging.
Introduction: Drugs of abuse, such as cocaine, affect different brain regions and lead to pathological memories. These abnormal memories may occur due to changes in synaptic transmissions or variations in synaptic properties of neurons. It has been shown that cocaine inhibits delayed rectifying potassium currents in affected brain regions and can create pathological memories.
View Article and Find Full Text PDFRecent advances in optical neuroimaging systems as a functional interface enhance our understanding of neuronal activity in the brain. High density diffuse optical topography (HD-DOT) uses multi-distance overlapped channels to improve the spatial resolution of images comparable to functional magnetic resonance imaging (fMRI). The topology of the source and detector (SD) array directly impacts the quality of the hemodynamic reconstruction in HD-DOT imaging modality.
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