Publications by authors named "Hadi Assadian"

The aim of this study was to investigate the effects of retro-cavity preconditioning with or without 17% ethylenediaminetetraacetic acid (EDTA) solution on root surface pH as well as dislodgement resistance of NeoMTA2 and MTA Flow retro-fills. Forty-eight single-rooted human incisors were selected. After completion of endodontic treatment, root-end resections were performed, and retro-cavities were prepared.

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The present case report aims to describe the successful management of pulp canal obliteration (PCO) in mandibular incisors using static-guided endodontics. A healthy 74-year-old man was referred by a prosthodontist for root canal treatment on teeth #31, #32, and #41. Periapical radiographs revealed the presence of periapical lesions as well as PCOs in teeth #31 and #41.

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To compare shock wave-enhanced emission photoacoustic streaming (SWEEPS) with sonic- and ultrasonically activated irrigation systems in removing biofilm from the root canal system. Fifty human single-canalled mandibular premolars were included in the study. After access cavity preparation, the root canals were prepared to a standardized size and taper.

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Antibacterial activity against endodontic pathogens is a desirable feature for root canal sealers. The objective of this study was to compare the antibacterial effect of three resin-based endodontic sealers (AH26, Adseal, and Beta RCS) against in vitro. The antibacterial properties of the sealers were assessed against using agar diffusion test (ADT) for fresh state (N=10) and direct contact test (DCT) for freshly-mixed and set states of the materials (N=10).

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Background: Several efforts have been made to improve mechanical and biological properties of calcium silicate-based cements through changes in chemical composition of the materials. This study aimed to investigate the physical (including setting time and compressive strength) and chemical (including calcium ion release, pH level) properties as well as changes in cytotoxicity of mineral trioxide aggregate (MTA) after the addition of 3 substances including CaCl, NaHPO, and propylene glycol (PG).

Methods: The systematic review was conducted in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA).

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Key Clinical Message: Management of supernumerary teeth fused to the labial surface of permanent maxillary central incisors would require a multidisciplinary approach comprising of endodontic treatment, periodontal recontouring, and cosmetic composite restoration.

Abstract: The reported cases of supernumerary teeth fused to the labial surface of maxillary central incisors are rare. Such cases need multidisciplinary approaches.

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Article Synopsis
  • Regenerative dentistry focuses on restoring dental and oral tissues, but lacks clear guidelines for the best materials in regenerative endodontic treatments (RET), with hydraulic calcium silicate-based cements (hCSCs) currently being the preferred option.
  • A systematic review evaluated various direct and indirect methods of using hCSCs in RET to determine which approach yielded better biological results for stem cells, following established PRISMA guidelines through extensive research databases.
  • The review analyzed 78 studies and found that indirect exposure methods using hCSCs like Biodentine and ProRoot MTA produced significantly better stem cell viability and regeneration outcomes compared to direct methods.
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Objective: The study aimed to compare the response of human dental pulp stem cells (hDPSCs) towards three hydraulic calcium silicate cements (HCSCs) by measuring cytotoxicity and expression of dentinogenic genes.

Methodology: Dental pulps of five impacted mandibular third molars were extirpated as a source for hDPSCs. Next to culturing, hDPSCs were subjected to fluorescence-activated cell sorting after the third passage to validate stemness of the cells.

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Dens invagination (DI) is a dental anomaly that can cause pulpal and periapical pathoses of the affected tooth. We describe the treatment of a healthy 18-year-old female with a chief complaint of recurrent facial swelling pertaining to a peg-shaped maxillary lateral incisor with DI. Examinations showed necrosis of the involved tooth with symptomatic apical periodontitis.

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The treatment objective for children with avulsed anterior teeth should concentrate on preserving the alveolar bone volume and contour. Posttraumatic external inflammatory root resorption (EIRR) is also a high-risk complication often observed in children. Regenerative endodontic procedure (REP) has been considered a successful treatment to arrest EIRR, especially in posttraumatic cases.

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Regenerative endodontic treatment (RET) is a valuable treatment for necrotic immature teeth with many advantages such as increasing root length and thickness of root wall. The success of RETs is based on healthy stem cells, suitable scaffolds, and growth factors and takes place when bacterial contamination is well controlled. The aim of this article is to address controversy in a case with multiple success criteria.

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Background: Conventional drug mixtures used in regenerative endodontic procedures have a toxic effect and no consensus has been reached about their best composition and concentration. Therefore, the aim of this study was to determine minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), and minimum biofilm inhibitory concentration (MBIC) of the antimicrobial preparations and to compare their antimicrobial efficacy on bovine dentin infected by .

Materials And Methods: For this original investigation, prepared concentrations (MIC, MBC, and MBIC) of triple antibiotic paste (TAP), double antibiotic paste (DAP), modified triple antibiotic paste (MTAP)-1, MTAP2, co-amoxiclav, and calcium hydroxide (CH) were added to the prepared bovine dentin blocks (which incubated in suspension previously) and incubated for 3 days.

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Background: Enterococcus faecalis, as a major microorganism in persistent/secondary infections of endodontically treated teeth, is less likely to be eliminated during endodontic therapy. In this study, the effect of root canal disinfection and anti-virulence activities of photodynamic inactivation (PDI) of E. faecalis utilizing reduced graphene oxide-curcumin (rGO-Cur) as a photosensitizing agent following irradiation with light-emitting diode (LED), as well as intracellular ROS production were evaluated on ex vivo biofilms of E.

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The demand for esthetic dental treatments is increasing in recent years mainly due to improved oral hygiene and better maintenance of oral health and teeth in older individuals. Bleaching of discolored anterior teeth is the most popular among esthetic dental treatments. Even individuals with sound teeth and adequate esthetics seek to have whiter teeth in the anterior region.

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Background: Laser-assisted bleaching uses laser beam to accelerate release of free radicals within the bleaching gel to decrease time of whitening procedure. The aim of this study was to compare the efficacy of power bleaching using Opalescence Xtra Boost® and laser bleaching technique using LaserSmile gel and diode laser as an activator in their tooth whitening capacity.

Material And Methods: Student t test showed that the laser bleaching group significantly outperformed the power bleaching group in changing ∆E (=0.

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Introduction: The aim of this study was to compare the accuracy of cone-beam computed tomography (CBCT), digital radiography and tooth sectioning in evaluating root canal morphology of mandibular incisors in an in vitro setting.

Methods And Materials: A total of 76 samples were imaged using CBCT, and digital radiography in straight and angled views. The samples were then sectioned at different distances from the apex for further visualization under stereomicroscope.

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Objectives: Cytotoxic effects of obturation materials were tested in presence and absence of endotoxin on human monocytes in vitro.

Materials And Methods: Human monocytes from THP-1 cell line were cultured. Three millimeters from the tip of each Resilon and gutta percha points were cut and directly placed at the bottom of the culture wells.

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A case with two simultaneous dens invaginations (DIs) and one dens evagination (DE) in a permanent maxillary lateral incisor is reported for the first time in a 21-year-old girl. DE known as talon cusp of the anterior teeth is a rare entity and its co-existence with DI has been reported scarcely in the literature. Simultaneous occurrence of two DIs with one DE has not been reported elsewhere.

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Objective: Use of rotary Nickel-Titanium (NiTi) instruments for endodontic preparation has introduced a new era in endodontic practice, but this issue has undergone dramatic modifications in order to achieve improved shaping abilities. Cone-beam computed tomography (CBCT) has made it possible to accurately evaluate geometrical changes following canal preparation. This study was carried out to compare canal centering ability and transportation of Twisted File and BioRaCe rotary systems by means of cone-beam computed tomography.

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Objectives: To eliminate microorganisms that are responsible for pulpal and periapical infections and to prevent reinfection of the root canal system an effective chemomechanical preparation by irrigants with sustained antimicrobial activity is beneficial. Hereby, we evaluated the residual antibacterial activity of MTAD after canal obturation at different time intervals.

Materials And Methods: A total of 120 human single-canalled anterior teeth were selected.

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Objective: A detailed knowledge of root canal anatomy is a prerequisite for successful endodontic treatment. Such information is highly dependent upon the ethnicity of the population of interest. Lack of sufficient national information concerning internal anatomy can lead clinicians to increase their rate of treatment success.

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Nowadays, bleaching of the teeth within the dental office is one of the most widespread techniques to correct tooth discoloration. Variability of the materials and techniques accompanied with the trend toward esthetic restorations with minimally invasive approaches are increasing. The use of laser in this regard has also been taken into consideration.

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Background: The aim of this study was to compare push-out bond strength of a new bioceramic endodontic sealer, EndoSequence BC sealer (Brasseler USA, Savannah, GA), used with gutta-percha in the presence or absence of phosphate-buffered saline solution (PBS) within the root canals.

Materials And Methods: Forty single-rooted human teeth were prepared and randomly divided into four groups. Samples in groups 1 and 2 were dried, but those in groups 3 and 4 were moistened with PBS before obturation.

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This study compared the push-out bond strength of mineral trioxide aggregate (MTA) and a new endodontic cement (NEC) as root-end filling materials in root-end cavities prepared by ultrasonic technique (US) or Er,Cr:YSGG laser (L). Eighty single-rooted extracted human teeth were endodontically treated, apicectomised and randomly divided into four following groups (n = 20): US/MTA, US/NEC, L/MTA and L/NEC. In US/MTA and US/NEC groups, root-end cavities were prepared with ultrasonic retrotip and filled with MTA and NEC, respectively.

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One of the most challenging issues following restoration is microleakage. The aim of this study was to investigate the effects of Er,Cr:YSGG laser with and without acid etching on microleakage of class V composite restorations. A total of 68 human intact premolars were selected, disinfected, and randomly allocated to four experimental groups (n = 16) as well as positive and negative controls (n = 2 each).

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