Real-world outcomes of patients with metastatic endocrine-responsive breast cancer receiving palbociclib-based combinations.

To describe treatment journey and clinical outcomes after palbociclib initiation in HR+/HER2- breast cancer patients across multiple lines. Adult patients (n = 559) were identified in a population-based study between January 2018 and June 2020. Median follow-up time was 41.

Trabeculectomy with Ex-PRESS implant versus Ahmed glaucoma valve implantation-a comparative study.

Aim: To compare the surgical outcomes of trabeculectomy with Ex-PRESS implant and Ahmed glaucoma valve (AGV) implantation.

Methods: Patients who underwent trabeculectomy with Ex-PRESS implants or AGV implantation separately were included in this retrospective chart review. Main outcome measures were surgical failure and complications.

Pterygium excision with conjunctival autograft: true survival rate statistics.

Purpose: To evaluate the factors influencing long-term survival rate (ie, probability of recurrence-free eye over time) after pterygium excision with conjunctival autograft.

Methods: A retrospective cohort study was performed. All patients who underwent excision of pterygium and conjunctival autograft at a single institution by the same surgeon during the years from 1997 to 2008 were included.

Takotsubo cardiomyopathy and QT interval prolongation: who are the patients at risk for torsades de pointes?

Objectives: QT interval prolongation is prevalent among patients with Takotsubo cardiomyopathy (TC), whereas torsades de pointes (TdP) has rarely been reported in these patients. We studied all peer-reviewed reports on TC-associated QT interval prolongation and all peer-reviewed reports on TC-associated TdP to characterize the clinical circumstances leading to TdP in patients with TC.

Methods: The literature search yielded 14 reports on TC-associated TdP and 26 reports on TC-associated QT interval prolongation.