Rapid-prototype titanium bone forms for vertical alveolar augmentation using bone morphogenetic protein-2: design and treatment planning objectives.

Reconstruction of complex maxillofacial defects where the use of bone morphogenetic protein-2 composite grafts may be preferred can be done using perforated titanium shells or forms that confine the graft material and simultaneously establish the desired shape of the augmentation without resorting to autogenous block bone grafting. Reported here is a method for creation of rapid-prototype titanium bone forms, which was developed from a software program, to reproduce bone morphology precisely. The technique and treatment planning objectives are elucidated, especially with regard to complex vertical augmentations.

Fabrication of printed titanium shells for containment of BMP-2 composite graft materials for alveolar bone reconstruction.

The engineering, design, manufacture, and rationale for use of printed titanium shells for alveolar bone reconstruction using BMP-2/ACS/allograft are described. This is proposed as a possible improvement to the current hand-configured mesh graft technique in common use today.

Removal of an extensive mandibular odontoma using an intraoral approach.

Odontomas, the most common odontogenic tumors, occur more frequently in the maxilla and are rarely larger than a tooth. They are usually found incidentally on routine dental radiographs during the second decade of life. The treatment of choice is surgical removal, and large tumors are challenging as damage may occur to surrounding anatomic structures.

Is entire removal of a post-traumatic temporomandibular joint ankylotic site necessary for an optimal outcome?

Purpose: Temporomandibular joint (TMJ) ankylosis that occurs after TMJ condylar fracture constitutes a treatment challenge. The purpose of the present study is shed light on an alternative treatment approach for certain such cases where the displaced condylar head or part of it can be detected in computed tomography. The leading principle of this protocol is accurate removal of the ankylotic mass only, leaving the condyle-disc apparatus un-touched.

Primary lymphoma of the mandible masquerading as bisphosphonate-related osteonecrosis of jaws.

A 66-year-old osteoporotic woman suffered from long-term mental paresthesia (numbness), facial swelling, and a nonhealing extraction site. Fulfilling the three clinical diagnostic criteria for bisphosphonate-related osteonecrosis of the jaw (BRONJ; exposed bone for at least 8 weeks, current bisphosphonate [risedronate] treatment, and no history of head and neck radiation therapy), she was diagnosed and treated accordingly. Nevertheless, a later histopathologic examination revealed malignant lymphoproliferative infiltration of large and intermediate cells.

Sunitinib related osteonecrosis of jaw: a case report.

A 58-year-old woman presented to the Oral and Maxillofacial Surgery Clinic experiencing severe limited mouth opening and exposed bone in the socket of the right mandibular third molar 8 months following the extraction of the tooth. The patient had been treated during the year before her presentation with sunitinib, an antiangiogenic drug, for renal cell carcinoma. The clinical, radiographic, and histologic picture of a chronic nonhealing extraction socket was consistent with osteonecrosis of the jaw (ONJ), although she had never been treated with bisphosphonates or corticosteroids.