Publications by authors named "Hadar Haim-Pinhas"

Introduction: Individuals with chronic kidney disease (CKD) are at increased risk of thrombotic events and bleeding. Acetylsalicylic acid (ASA), an effective antiplatelet agent, is one of the most frequently used medications for both primary and secondary prevention of cardiovascular disease (CVD). However, it can also contribute to bleeding events due to its inherent antiplatelet effect.

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Article Synopsis
  • * This study analyzed 2,169 CKD patients, comparing aspirin users to non-users, focusing on outcomes like cardiovascular events, bleeding events, and overall mortality over an average follow-up of nearly 5 years.
  • * Results showed no significant differences in mortality or bleeding between aspirin users and non-users, and while aspirin users had higher cardiovascular event rates initially, the difference disappeared after adjusting for risk factors, suggesting aspirin may not provide the expected protective benefits in CKD patients.
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Objective: Congenital MPHD is a rare condition caused by mutations in pituitary transcription factors genes: PROP1, POU1F1 (PIT1), HESX1, LHX3, LHX4.

Design: We evaluated in a retrospective study the effects on growth and development in 29 patients with congenital MPHD (cMPHD), during hGH replacement therapy alone and combined with sex hormones. Twenty nine patients with cMPHD were included and diagnosed, treated and followed in our clinic from diagnosis to adult age.

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