Publications by authors named "Hadar Asraf"
Article Synopsis
- Positive-sense single-stranded RNA viruses, particularly beta-CoVs like SARS-CoV-2, can jump from animals to humans, posing risks to public health and economies, highlighted by the ongoing pandemic.* -
- Current treatments mainly involve vaccines and antibodies, but the emergence of new variants that may resist these measures prompts the need for innovative antiviral strategies.* -
- The study introduces a synthetic mRNA therapy called PSCT, which competes with the viral genome to reduce SARS-CoV-2 replication in human cell cultures, demonstrating potential for developing new antiviral treatments.*
Emerging SARS-CoV-2 (SC-2) variants with increased infectivity and vaccine resistance are of major concern. Rapid identification of such variants is important for the public health decision making and to provide valuable data for epidemiological and policy decision making. We developed a multiplex reverse transcriptase quantitative PCR (RT-qPCR) assay that can specifically identify and differentiate between the emerging B.
View Article and Find Full Text PDFFumarate hydratase (FH, fumarase), is a tricarboxylic acid cycle enzyme localized in the mitochondrial matrix. However, a common theme, conserved from yeast to human, is the existence of a large cytosolic population of FH. FH has been shown to function as a tumor suppressor gene and is now implicated in various diseases.
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