Background: Complications after body-contouring surgery are a field of great interest. Recognition of patient-related characteristics contributing to a greater risk for complication is of the utmost importance in improving the quality of care and safety profile of aesthetic procedures. Previous history of cesarean section (CS) and its impact on adverse events after abdominoplasty has yet to be investigated and defined.
View Article and Find Full Text PDFHarnessing energy from descending greywater (GW) in tall buildings (TBs) is an innovative concept that combines water management with renewable energy generation and applying simulation methods. This study proposes a novel approach to enhancing sustainable energy recovery in TBs by capitalizing on the kinetic energy inherent in descending GW. Greywater, derived from non-toilet fixtures such as showers, bathroom sinks, and washing machines, offers a readily accessible source of potential energy due to its gravity-driven flow through the plumbing system.
View Article and Find Full Text PDFBackground: Silicone implants are by far the most widely used implant globally for breast augmentation. Despite technological advancements, complications persist, with silicone lymphadenopathy (siliconoma) being a noteworthy concern. This phenomenon has been inadequately addressed in the existing literature.
View Article and Find Full Text PDFObjective: This research assesses the utilization of sieved olive pulp (SOP) in the diet of growing rabbits through the use of an exogenous enzyme or dry yeast as a pretreatment.
Materials And Methods: One hundred sixty-eight male V-Line rabbits aged 5 weeks (weighing 550 ± 25 gm) were randomly divided into seven groups with eight replicates each as follows: the control group was fed a basal diet without supplementation; while the other six groups were fed basal diets containing 20% and 25% of SOP and supplemented with 0.1 gm/kg Econase (E), 0.
MicroRNAs (miRNAs) play a crucial role in mRNA regulation. Identifying functionally important mRNA targets of a specific miRNA is essential for uncovering its biological function and assisting miRNA-based drug development. Datasets of high-throughput direct bona fide miRNA-target interactions (MTIs) exist only for a few model organisms, prompting the need for computational prediction.
View Article and Find Full Text PDFJ Plast Reconstr Aesthet Surg
January 2024
Introduction: Breast augmentation remains one of the most prevalent procedures in plastic surgery. While most patients experience high satisfaction with the outcomes, a subset may encounter various complications or dissatisfaction with achieved results necessitating subsequent surgical intervention including implant removal or exchange.
Materials And Methods: We collected information from three pivotal private medical centers in Israel where a considerable number of breast surgeries are performed.
Objective: We describe the characteristics and outcomes of pediatric rapid response team (RRT) events within a single institution, categorized by reason for RRT activation (RRT triggers). We hypothesized that events with multiple triggers are associated with worse outcomes.
Patients And Methods: Retrospective 3-year study at a high-volume tertiary academic pediatric hospital.
In an ongoing study of the striped hyena (), we observed that in the nine different females, alloparenting by the daughters of a previous litter was not uncommon and occurred on fifteen different occasions, twice with two helpers. Alloparenting persisted from when the cubs are approximately a month old until they reach the age when they go out foraging with their mothers at 10-12 months. Helpers perform most maternal duties, except suckling, even in the mother's presence.
View Article and Find Full Text PDFJ Plast Reconstr Aesthet Surg
May 2023
Background: Breast implant rupture is associated with multiple risk factors such as implant age, manufacturer, and a history of trauma to the breast. However, the exact mechanism of breast implant rupture remains unclear. We hypothesize that repetitive minor mechanical forces on the implant collectively play a significant role in the cascade that eventually leads to its rupture.
View Article and Find Full Text PDFThe striped hyena (Hyaena hyaena) is considered "Near Threatened" globally and "Vulnerable" in the Middle East. In Israel, the species has experienced extreme population fluctuations owing to poisoning campaigns during the British Mandate (1918-1948) which were also further exacerbated by the Israeli authorities in the mid-twentieth century. We collated data from the archives of the Israel Nature and Parks Authority for the past 47 years to elucidate the temporal and geographic trends of this species.
View Article and Find Full Text PDFThe diet and breeding success of Eagle Owls () have been suggested to vary at different latitudes. However, it is still unclear whether and how these relationships exist at lower latitudes outside of Europe. We therefore studied the diet and breeding success of Eagle Owls during four breeding seasons at 14 nests in the Judea region, Israel.
View Article and Find Full Text PDFBackground: The rapid evolution of the social media platform has had a major effect on the field of medicine.
Objective: To identify patterns, trends and patients' concerns before and after aesthetic surgeries involving breast implants, by analyzing social media posts.
Methods: We examined comments posted on popular Israeli online public forums between January 2019 and May 2021, regarding: breast augmentation, mastopexy-augmentation and breast implant removal.
Background: Breast implant illness (BII) is a rising concern among many patients. Although not fully understood, a connection between silicone breast implants and systemic diseases may be present. This connection may influence the types of breast surgeries performed.
View Article and Find Full Text PDFBackground: The common recommendation for female abdominoplasty candidates is to conclude family planning before undergoing the procedure. However, no evidence demonstrates a correlation between aesthetic outcome compromise, risk for fetal complications, or risk for maternal complications when abdominoplasty is followed by pregnancy.
Objectives: The aim of this study was to evaluate maternal, fetal, and aesthetic outcomes among pregnant females with a history of abdominoplasty.
Personalized cancer treatment based on specific mutations offers targeted therapy and is preferred over "standard" chemotherapy. Proteinoid polymers produced by thermal step-growth polymerization of amino acids may form nanocapsules (NCs) that encapsulate drugs overcoming miscibility problems and allowing passive targeted delivery with reduced side effects. The arginine-glycine-glutamic acid (RGD) sequence is known for its preferential attraction to αvβ3 integrin, which is highly expressed on neovascular endothelial cells that support tumor growth.
View Article and Find Full Text PDFProteinoids are non-toxic biodegradable polymers prepared by thermal step-growth polymerization of amino acids. Here, P(RGD) proteinoids and proteinoid nanocapsules (NCs) based on D-arginine, glycine, and L-aspartic acid were synthesized and characterized for targeted tumor therapy. Doxorubicin (Dox), a chemotherapeutic drug used for treatment of a wide range of cancers, known for its adverse side effects, was encapsulated during self-assembly to form Dox/P(RGD) NCs.
View Article and Find Full Text PDFFluorescent carbon dots (CDs) play a versatile role in materials science. Herein, we have developed alginate-derived nitrogen-doped CDs as a drug carrier and a toughening agent for hydrogels by a microwave-assisted method. In the first phase of work, we carried out covalent conjugation of the drug onto the CD surface for controlled delivery of drug molecules, and in the second phase of work, we demonstrated how CDs could act as a toughening agent as well as a viscosity modifier for poly(acrylic acid--methacrylamide) copolymer hydrogels.
View Article and Find Full Text PDFRGD sequence is a tripeptide composed of three amino acids: arginine (R), glycine (G), and aspartic acid (D). The RGD peptide has a high affinity to the integrin alpha v beta 3, which is overexpressed on the membrane of many cancer cells and is attracted to areas of angiogenesis. Proteinoids are biodegradable polymers based on amino acids which are formed by bulk thermal step-growth polymerization mechanism.
View Article and Find Full Text PDFProteinoids are non-toxic biodegradable polymers based on thermal step-growth polymerization of natural or synthetic amino acids. Hollow proteinoid nanoparticles (NPs) may then be formed a self-assembly process of the proteinoid polymers in an aqueous solution. In the present article polymers and NPs based on d-arginine, glycine and l-aspartic acid, poly(RGD), were synthesized for tumor targeting, particularly due to the high affinity of the RGD motif to areas of angiogenesis.
View Article and Find Full Text PDFCathepsins (CTSs) are multifunctional proteins that can play prominent roles in cancer progression and metastasis. In this systematic review, we compared the prognosis of CTS subtypes overexpression in leukemia and solid tumors, and investigated the effect of different factors on CTS prognosis. We systematically searched published articles indexed in PubMed, Scopus, Cochrane library, ISI Web of Science, and EmBase databases from February 2000 until January 2020.
View Article and Find Full Text PDFACS Appl Mater Interfaces
May 2020
Micropatterns of conductive polymers are key for various applications in the fields of flexible electronics and sensing. A bottom-up method that allows high-resolution printing without additives is still lacking. Here, such a method is presented based on microprinting by the laser-induced microbubble technique (LIMBT).
View Article and Find Full Text PDFBackground: The anterior aspect of the auricle is a complex 3-dimensional structure. Each anatomical component in this region has an essential role in the aesthetic appearance of the ear and face. The reconstruction of defects in this region is challenging because of the lack of mobile, excess skin for primary closure, and the inability to skin graft overexposed cartilage.
View Article and Find Full Text PDFThe shape and porosity of polymeric colloids are two properties that highly influence their ability to accomplish specific tasks. For micro-sized colloids, the control of both properties was demonstrated by the photo-induced phase separation of droplets of NOA81-a thiol-ene based UV-curable adhesive-mixed with acetone, water, and polyethylene glycol. The continuous phase was perfluoromethyldecalin, which does not promote phase separation prior to UV activation.
View Article and Find Full Text PDFNatural killer (NK) cells play an essential role in the immune response to infections, inflammations, and malignancies. Recent studies suggest that NK cell surface receptors and cytokines are the key points of the disease development and protection. We hypothesized that the interactions between NK cell receptors and targeted cells construct an eventual niche, and this niche has an eventual profile in various autoimmune diseases and cancers.
View Article and Find Full Text PDFComplex karyotype (CK) is a poor prognosis factor in hematological malignancies. Studies have shown that the presence of CK in myelodysplastic syndrome (MDS) can be associated with MDS progression to acute myeloid leukemia. The goal of this review was to examine the relationship between different types of CK with MDS, as well as its possible role in the deterioration and progression of MDS to leukemia.
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