Objective: The purpose of our study was to assess the effect of an i.v. injection of iodinated radiographic contrast medium on human renal blood flow using cine phase-contrast MRI.
View Article and Find Full Text PDFPurpose: To present a method for calculating split renal function solely from routine triphasic helical computed tomography (CT).
Subjects And Methods: We retrospectively included 26 adult patients who received renal scintigraphy and triphasic CT within 4 weeks in the years 2003 and 2004. All scans were performed using a standard abdominal protocol.
We determined the optimum gadolinium (Gd)-DTPA dose and time window for calculating the glomerular filtration rate (GFR) using contrast-enhanced (CE) dynamic MRI and the Patlak plot technique. Twelve adult volunteers with healthy kidneys were included in the study. As a reference method the GFR was measured by iopromide plasma clearance.
View Article and Find Full Text PDFInsulin independence after islet transplantation has been significantly improved by using new steroid-free immunosuppressive protocols and increased islet mass. Only little is known about the influence on the morphology of the liver of intraportally transplanted islets. We describe a case of disseminated periportal fatty degeneration after allogeneic intraportal islet transplantation (ITx).
View Article and Find Full Text PDFPurpose: To evaluate the feasibility of micro computed tomography (CT) for analysis of the coronary artery wall.
Materials And Methods: With micro CT, two-dimensional transverse images were generated from 10 human autopsy specimens of coronary arteries (2.5-3.
We present the case of a 22-year-old patient who had splenectomy in childhood after trauma and had a known chronic active infection with hepatitis C. Imaging procedures in different radiologic modalities diagnosed diffuse intraabdominal splenosis. Splenosis is a rare, severe complication of splenic trauma or surgery, but the pathogenesis is not clear.
View Article and Find Full Text PDFPurpose: To determine the accuracy of the two-point Patlak plot in the calculation of glomerular filtration rate (GFR).
Materials And Methods: Fifty patients without acute renal disorder were included. GFR was calculated by using a two-point Patlak plot technique.
Purpose: To determine the accuracy of single-kidney glomerular filtration rate (GFR) determination using contrast-enhanced dynamic magnetic resonance imaging (MRI) and the Rutland-Patlak plot technique.
Materials And Methods: Twenty-eight adult patients were included. As reference method, the GFR was measured by plasma clearance using a small bolus injection of iopromide.
We report on a case of penile epithelioid sarcoma in a 29-year-old man presenting with a dorsal penile plaque that primarily was misdiagnosed as Peyronie's disease. Although the initial clinical findings of these two different entities appear similar, the consequence for the patient is severe. The only way of differentiating these disorders are histological findings.
View Article and Find Full Text PDFObjective: We measured the single-kidney glomerular filtration rate (GFR) with a two-point Patlak plot technique based on multiphasic CT in patients with hydronephrosis or pyelonephritis or both. The question we sought to answer in our study was, Does increased interstitial space as measured with the Patlak plot technique cause overestimation of GFR?
Subjects And Methods: Twenty adult patients treated with percutaneous nephrostomy were studied. The CT protocol consisted of an unenhanced scan and three subsequent scans obtained 38, 71, and 102 sec after the initiation of the contrast medium injection.
Purpose: Glomerular filtration rate (GFR) can be measured by iopromide plasma clearance. As an injection of 120 ml nonionic contrast medium is expensive and especially in patients with nephropathy potentially nephrotoxic, we investigated whether iopromide plasma clearance could be measured using a tenth of that dose as 'low-dose' clearance.
Material And Methods: Fifty adult patients scheduled for CT were recruited.
Objective: To compare the value of magnetic resonance imaging (MRI) with palpation and ultrasound in the evaluation of plaque formation in Peyronie's disease.
Methods: 57 patients underwent a standardized diagnostic procedure to evaluate plaque formation consisting of palpation and ultrasonography (7.5 MHz).
In the present study, we investigated a new sonographic test to confirm or exclude partial common bile duct (CBD) obstruction, hereinafter called "dynamic cholangio-cholecysto sonography (DCCS)." Healthy controls (6) and patients with low- to intermediate probability for partial CBD obstruction (17) were investigated. DCCS started with three baseline masurements of gallbladder volume and CBD diameter, which were then repeated every 2 to 3 min for 45 min during a 30-min infusion of ceruletid.
View Article and Find Full Text PDFClin Physiol Funct Imaging
March 2002
Objective: The pharmacokinetics of iopromide were analysed using a two-compartment model. The optimal point of time for blood withdrawal for calculation of a one-sample clearance was determined.
Methods: Plasma concentration of iodine was measured up to 8 h postinjection (p.
Objective: Single kidney contrast media clearance was measured using multiphasic CT in patients without acute renal disorder. The aim of this study was to answer two questions. First, how accurate is CT in measuring contrast media clearance compared with plasma clearance? Second, is the accuracy of CT clearance measurements dependent on the timing of CT scans with respect to the contrast media injection?
Subjects And Methods: Fifty adult patients without acute renal disorder were included in this study.
Objective: We present preliminary results of a new method (hereinafter called 'CT-clearance') to measure single kidney contrast media clearance by performing multiphasic helical CT of the kidneys. CT-clearance was calculated according to an extension of the Patlak-Plot. In contrast to prior investigators, who repeatedly measured a single slice, this method makes it possible to calculate single kidney clearance from at least three spiral CTs, utilizing the whole kidney volume.
View Article and Find Full Text PDFBlood isotone contrast media is considered to be less toxic to vascular and pancreatic duct endothelium than high-osmolar contrast media. In this study we assessed the impact of a low-osmolar contrast agent compared with a blood isotone product on pancreatic damage induced by endoscopic retrograde cholangiopancreatography (ERCP) and endoscopic retrograde sphincterotomy (EST). In a prospective trial 42 consecutive ERCP/EST patients were randomized to receive either iopromid, a low-osmolar non-ionic contrast agent (770 mosmol/kg H2O), or iotrolan, a blood-isotone non-ionic product (320 mosmol/kg H2O).
View Article and Find Full Text PDFNuklearmedizin
April 1999
Aim: In this paper we present a new method to measure the renal slope-clearance of Tc-99m-MAG-3 in a single-shot model (Excretion-clearance).
Methods: A renal scintigraphy with Tc-99m-MAG-3 was performed in 22 patients. The excreted activity of the tracer in the kidneys and the bladder was dynamically measured using a double-head gamma-camera.
This paper describes a simulation program for ECG modelling for use with IBM-compatible computers. The underlying three-dimensional heart model comprising 4,500 units complies with the four criteria for valid ECG-forward modelling established by Gulrajani in 1989: accurate cardiac geometry, element-to-element propagation of the excitation stimulus, definition of action potentials and a suitable means of computing the surface ECG potentials from those measured in the model. For evaluation of the model, simulations of physiological excitation and of pathologies (Wolff-Parkinson-White syndrome, complete AV-block, inferior wall ischaemia) were examined.
View Article and Find Full Text PDFTo test the hypothesis that the presence of ventricular late potentials in the highly amplified, averaged and filtered surface electrocardiogram (ECG) can be predicted from the conventional surface ECG, 211 patients with and without previously documented sustained ventricular tachycardia outside the acute phase of myocardial infarction were studied. The presence of left ventricular akinesia or aneurysm was significantly correlated with the ECG score (based on Q wave duration, R wave duration and amplitude ratio). The mean ECG score in patients without ventricular tachycardia was 3.
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