Antihistaminergic and Anticholinergic Properties of the Root Bark Aqueous Extract of (Ebenaceae) on Hypersecretion of Gastric Acid Induced in Wistar Rats.

Objective: The objective of this study was to elucidate the antisecretory mechanism of the root bark aqueous extract of (RBAEDM) in Wistar rats. . RBAEDM was tested on three experimental animal models of gastric acid hypersecretion including pyloric ligation (PL), PL with histamine, and carbachol pretreatments.