Thermoluminescent Characteristics of GR-200, TLD-700H and TLD-100 for Low Dose Measurement: Linearity, Repeatability, Dose Rate and Photon Energy Dependence.

Background: The dose values obtained from procedures of diagnostic radiology are relatively low. To accurately and precisely measure the dose values in this dose range, it is necessary to know the characteristics of dosimeters.

Objective: The aim of this study was to evaluate several thermoluminescent characteristics of GR-200, TLD-700H and TLD-100 for low dose measurement.

Study on the Dose Enhancement of Gold Nanoparticles When Exposed to Clinical Electron, Proton, and Alpha Particle Beams by Means of Geant4.

Background: Various factors effecting deposited energy and dose enhancement ratio (DER) in the simplified model of cell caused by the interaction of a cluster of gold nanoparticles (GNPs) with electron beams were assessed, and the results were compared with other sources through Geant4 Monte Carlo simulation toolkit.

Method: The effect of added GNPs on the DNA strand breaks level, irradiated to electron, proton, and alpha beams, is assessed.

Results: Presence of GNPs in the cell makes DER value more pronounced for low-energy photons rather than electron beam.

Measuring the dose-width product and proposing the local diagnostic reference level in panoramic dental radiography: a multi-center study from Iran.

Objective: Although radiation exposure associated with dental radiography is relatively low, patient exposure must be kept practically low. Therefore, it is necessary for each country to establish its own diagnostic reference levels (DRLs) suitable for its equipment and practice. In the present study, dose-width product (DWP) values for panoramic dental radiography were measured and a local DRL was established.

Mitigation of Radiation-induced Gastrointestinal System Injury using Resveratrol or Alpha-lipoic Acid: A Pilot Histopathological Study.

Aim: In this study, we aimed to determine possible mitigation of radiationinduced toxicities in the duodenum, jejunum and colon using post-exposure treatment with resveratrol and alpha-lipoic acid.

Background: After the bone marrow, gastrointestinal system toxicity is the second critical cause of death following whole-body exposure to radiation. Its side effects reduce the quality of life of patients who have undergone radiotherapy.

Evaluation of Ameliorative Potential of Vitamins E and C on DNA Double Strand Break (DSB) in Patients Undergoing Computed Tomography (CT): A Clinical Study.

Computed tomography (CT) is one of the most important diagnostic X-ray procedures which plays an important role in increasing the patient dose values. The purpose of this clinical study was to evaluate the efficacy of vitamins E and C in lowering down the level of DNA double strand break (DSB) caused by CT scan. Sixty patients for abdomen/pelvic enhanced CT scan were randomly assigned to placebo (control), vitamin C, and vitamin E groups.

Radiation-Induced Dual Oxidase Upregulation in Rat Heart Tissues: Protective Effect of Melatonin.

: Radiation-induced heart injury can lead to increased risk of heart failure, attack, and ischemia. Some studies proposed IL-4 and IL-13 as two important cytokines that are involved in late effects of ionizing radiation. On the other hand, these cytokines may, through upregulation of and , induce chronic oxidative stress, inflammation, and fibrosis.

Melatonin Attenuates Upregulation of Duox1 and Duox2 and Protects against Lung Injury following Chest Irradiation in Rats.

Objective: The Lung is one of the most radiosensitive organs of the body. The infiltration of macrophages and lymphocytes into the lung is mediated via the stimulation of T-helper 2 cytokines such as IL-4 and IL-13, which play a key role in the development of fibrosis. It is likely that these cytokines induce chronic oxidative damage and inflammation through the upregulation of and , which can increase the risk of late effects of ionizing radiation (IR) such as fibrosis and carcinogenesis.

Circular Mitochondrial DNA: A Geant4-DNA User Application for Evaluating Radiation-induced Damage in Circular Mitochondrial DNA.

Background: The aim of this study was to develop a nucleotide geometrical model of the circular mitochondrial DNA (mt-DNA) structure using Geant4-DNA toolkit to predict the radiation-induced damages such as single-strand breaks (SSB), double-strand breaks (DSB), and some other physical parameters.

Methods: Our model covers the organization of a circular human mt genetic system. The current model includes all 16,659 base pairs of human mt-DNA.