Aflatoxin B1 (AFB1) contamination of food crops pose severe public health risks, particularly in decentralized agricultural systems common in low-resource settings. Effective monitoring tools are critical for mitigating exposure, but their adoption is limited by barriers such as cost, infrastructure, and technical expertise. The objectives of this study were: (1) to evaluate common AFB1 detection methods, including enzyme-linked immunosorbent assays (ELISA) and lateral-flow assays (LFA), validated via high-performance liquid chromatography (HPLC), focusing on their suitability for possible applications in decentralized, low-resource settings; and (2) to conduct a barriers-to-use assessment for commonly available AFB1 detection methods and their applicability in low-resource settings.
View Article and Find Full Text PDFFront Comput Neurosci
January 2025
Marketing plays a vital role in the success of a business, driving customer engagement, brand recognition, and revenue growth. Neuromarketing adds depth to this by employing insights into consumer behavior through brain activity and emotional responses to create more effective marketing strategies. Electroencephalogram (EEG) has typically been utilized by researchers for neuromarketing, whereas Eye Tracking (ET) has remained unexplored.
View Article and Find Full Text PDFRNA modifications play crucial roles in immune system development and function, with dynamic changes essential for diverse cellular processes. Innovative profiling technologies are invaluable for understanding the significance of these modifications in immune cells, both in healthy and diseased states. This review explores the utility of such technologies in uncovering the functions of RNA modifications and their impact on immune responses.
View Article and Find Full Text PDFBackground: The rapid advancement of artificial intelligence (AI) has revolutionized both medical education and healthcare by delivering innovative tools that enhance learning and improve overall outcomes. The study aimed to assess students' perceptions regarding the credibility and effectiveness of AI as a learning tool and to explore the dynamics of integrating AI in medical education.
Methodology: A cross-sectional study was carried out across medical colleges in Pakistan.
Objective: The objective of the study is to assess the satisfaction level of doctors regarding their competence in the blood transfusion process and their reflection on training at the undergraduate level.
Background: Transfusion errors due to suboptimal knowledge and lack of training can lead to grave outcomes. Therefore, to optimize patient care, a thorough understanding of transfusion medicine basics is highly imperative for all medical graduates.
Maize is a staple crop worldwide, essential for food security, livestock feed, and industrial uses. Its health directly impacts agricultural productivity and economic stability. Effective detection of maize crop health is crucial for preventing disease spread and ensuring high yields.
View Article and Find Full Text PDFThe growing interest in plant-derived compounds and synthesis of metallopolymer nanocomposites (MPNCs) especially silver chitosan nanocomposites (AgCS-NCs) emerges as a useful platform to encapsulate and deliver plant-based anticancer drugs. This work presents the synthesis of AgCS-NCs by using Moringa oleifera aqueous leaf extract (MOAE) and the effect of concentration of MOAE on physicochemical properties of AgCS-NCs followed by its anticancer effect on MCF-7 cell line. The results of UV-visible spectroscopy (UV-Vis) and Scanning electron microscopy (SEM) showed successful formation of AgCS-NCs.
View Article and Find Full Text PDFThis study aimed to investigate the potential of Pichia kudriavzevii (PK), a newly discovered yeast strain, in alleviating the deleterious effects induced by aflatoxins on broilers. Eighty one-day-old broiler chicks were divided into four groups and subjected to various combinations of aflatoxin dosages at 300 μg/kg of feed alongside PK supplementation at 1 g/kg of feed. Assessment encompassed a comprehensive array of parameters including performance metrics, hepatic and renal biomarkers, interleukin concentrations, blood cell counts, hemoglobin concentration, packed cell volume, antibody response to sheep red blood cells, lymphoproliferative response to PHA-P, phagocytic response utilizing the carbon clearance assay system, as well as evaluation of oxidants and antioxidants.
View Article and Find Full Text PDFBackground: Hand-arm Vibration Syndrome (HAVS) is a disorder caused by prolonged exposure to hand-held vibrating instruments, commonly observed in industrial contexts such as mining, construction, and manufacturing. It involves symptoms affecting the musculoskeletal, neurological, and vascular systems of the arm and hand.
Purpose: The main aim of this study is to determine the prevalence of HAVS among laborers working in the Khewra salt mines.
Aims: The "2 to 10% strain rule" for fracture healing has been widely interpreted to mean that interfragmentary strain greater than 10% predisposes a fracture to nonunion. This interpretation focuses on the gap-closing strain (axial micromotion divided by gap size), ignoring the region around the gap where osteogenesis typically initiates. The aim of this study was to measure gap-closing and 3D interfragmentary strains in plated ovine osteotomies and associate local strain conditions with callus mineralization.
View Article and Find Full Text PDFBacterial skin infections, particularly pyoderma and otitis externa, are widespread in dogs, primarily caused by and species. This study evaluates the prevalence and types of bacterial pathogens in affected dogs in South Korea using a meta-analytical approach. Following the PRISMA guidelines, five electronic databases were searched for relevant studies published between 1990 and 2024.
View Article and Find Full Text PDFBackground To evaluate the accuracy and optimal C-reactive protein (CRP) level for detecting anastomotic leak (AL) in patients following elective colorectal resection. Methods A retrospective data collection of patients undergoing elective colorectal resection with primary anastomosis at a single institution was performed. Data were collected between June 2021 and November 2022.
View Article and Find Full Text PDFBackground: Laparoscopic-assisted (LTAP) and ultrasound-guided (UTAP) transversus abdominis plane (TAP) blocks are widely used for postoperative analgesia in laparoscopic cholecystectomy (LC), yet their comparative effectiveness remains unclear. The aim of this meta-analysis was to systematically evaluate and compare postoperative outcomes of LTAP and UTAP in LC.
Materials And Methodology: A comprehensive literature search of five electronic databases was conducted from the inception of the paper till 2 June 2024 following PRISMA guidelines.
Fishmeal (FM) is a key component of commercial fish feeds, but due its unsustainable supply, the search for quality alternatives of FM has become a significant area of investigation worldwide. The insect-based proteins such as black soldier fly larvae (BSFL) are being recognized as an alternative ingredient. However, anti-nutritional factors in these alternatives may negatively affect nutrient utilization in fish.
View Article and Find Full Text PDFThe escalating antimicrobial resistance (AMR) in highly virulent poses a significant public health concern in Asia. Profiling the antibiogram of this pathogen is crucial for revealing its complex AMR patterns and guiding the selection of appropriate medications. Although previous studies have provided valuable insights regarding AMR, they are constrained by limited sample diversity, inconsistent methodologies, and insufficient regional data.
View Article and Find Full Text PDFAquaponics combines aquaculture and hydroponics, offering methods to produce fish and plants. However, optimization of its nitrogen transformation processes, which would lead to higher nitrogen utilization efficiency (NUE) and lower nitrous oxide (NO) emission, is still a daunting challenge. This study investigated these issues by using biochar and zerovalent iron (ZVI) with low (LD) and high (HD) doses.
View Article and Find Full Text PDFIndian J Dermatol Venereol Leprol
November 2024
This research utilizes carboxymethyl cellulose (CMC) as a renewable feedstock in polyurethane synthesis, offering improved thermal stability and potential for biomedical applications. In this study, a series of CMC-based polyurethanes was synthesized by using a step-growth polymerization reaction. The initial step involved the reaction of isophorone diisocyanate (IPDI) with hydroxy-terminated polybutadiene (HTPB) to prepare an isocyanate (-NCO) terminated prepolymer.
View Article and Find Full Text PDFBackground: Obturator hernia is a rare type of pelvic hernia that often presents with vague symptoms that can easily be confused with other conditions. Delayed diagnosis can lead to increased morbidity and complications.
Case Presentation: A 67-year-old female with a history of rheumatoid arthritis presented with escalating right knee pain, unresponsive to increasing doses of opioids.
SAGE Open Med Case Rep
November 2024
Five cases of non-neuronal granular cell tumours of the oral cavity are documented in the literature. Additionally, one case of a non-neuronal granular cell tumour with features of malignancy was described. A malignant granular cell tumour is a rare neoplasm and counterpart of a benign granular cell tumour.
View Article and Find Full Text PDF