Coffee intake may promote sudomotor function activation the contribution of caffeine.

Objectives: To determine whether drinking coffee with caffeine accelerates the sympathetic response to acetylcholine (ACh).

Methods: Tests were performed twice at 1-week intervals following the intake of coffee. Subjects were randomly divided into two groups: Group A was administered 16 fluid oz of water (CON), while Group B was given 16 fluid oz of coffee (Coffee).